Development Level

Tbio 104 | 11,445
Tchem 33 | 1,598
Tdark 21 | 6,588
Tclin 15 | 613

Collection

Kinase: IDG Consortium (Target... 4 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal behavior 6 | 298
preweaning lethality, incomple... 6 | 499
abnormal embryo size 5 | 220
prenatal lethality prior to he... 5 | 87
decreased lean body mass 4 | 135
enlarged heart 4 | 210
hyperactivity 4 | 148
abnormal bone structure 3 | 187
abnormal craniofacial morpholo... 3 | 33
decreased bone mineral content 3 | 151
hypoactivity 3 | 132
increased circulating alkaline... 3 | 122
increased circulating calcium ... 3 | 34
abnormal eye morphology 2 | 68
abnormal forebrain morphology 2 | 10
abnormal gait 2 | 69
abnormal hindbrain morphology 2 | 10
abnormal midbrain morphology 2 | 10
abnormal neural tube closure 2 | 46
abnormal retinal blood vessel ... 2 | 26
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased circulating amylase ... 2 | 28
decreased circulating aspartat... 2 | 34
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased circulating sodium l... 2 | 22
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased leukocyte cell numbe... 2 | 73
decreased vertical activity 2 | 208
edema 2 | 59
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased circulating total pr... 2 | 28
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
thrombocytopenia 2 | 56
abnormal body wall morphology 1 | 9
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal liver morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
decreased IgG1 level 1 | 8
decreased body length 1 | 101
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
limb grasping 1 | 41
microphthalmia 1 | 26
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 103 | 11,493
osteosarcoma 97 | 7,950
ovarian cancer 96 | 8,520
psoriasis 77 | 6,694
glioblastoma 67 | 5,792
lung cancer 67 | 4,740
medulloblastoma, large-cell 61 | 6,241
tuberculosis 53 | 2,010
Cancer 52 | 2,499
invasive ductal carcinoma 52 | 2,951
ependymoma 48 | 4,679
malignant mesothelioma 46 | 3,232
Breast cancer 45 | 3,578
atypical teratoid / rhabdoid tumor 45 | 5,112
lung carcinoma 45 | 2,843
group 3 medulloblastoma 44 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,989
non-small cell lung cancer 43 | 2,890
pancreatic cancer 43 | 2,398
adult high grade glioma 41 | 3,801
lung adenocarcinoma 41 | 2,716
interstitial cystitis 40 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 38 | 2,955
primitive neuroectodermal tumor 38 | 3,035
Astrocytoma, Pilocytic 36 | 3,081
Rheumatoid arthritis 34 | 1,191
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
oligodendroglioma 31 | 2,850
ulcerative colitis 31 | 1,819
breast carcinoma 30 | 1,638
pituitary cancer 30 | 1,972
cystic fibrosis 28 | 1,696
ductal carcinoma in situ 28 | 1,745
Pick disease 27 | 1,894
Kidney cancer 26 | 2,613
cutaneous lupus erythematosus 25 | 1,057
astrocytic glioma 23 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
Multiple myeloma 22 | 1,332
Waldenstrons macroglobulinemia 22 | 765
juvenile dermatomyositis 22 | 1,187
colon cancer 21 | 1,478
subependymal giant cell astrocytoma 21 | 2,287
diabetes mellitus 20 | 1,728
group 4 medulloblastoma 20 | 1,855
Multiple Sclerosis 19 | 540
astrocytoma 18 | 1,146
acute quadriplegic myopathy 17 | 1,158
dermatomyositis 17 | 966
Liver Cirrhosis, Experimental 16 | 769
esophageal adenocarcinoma 16 | 737
primary pancreatic ductal adenocarcinoma 16 | 1,109
Atopic dermatitis 15 | 952
Crohn's disease 15 | 321
acute myeloid leukemia 15 | 783
Obesity 14 | 678
active ulcerative colitis 14 | 764
adrenocortical carcinoma 14 | 1,428
gastric carcinoma 14 | 807
hepatocellular carcinoma 13 | 547
medulloblastoma 13 | 720
pediatric high grade glioma 13 | 1,064
primary Sjogren syndrome 13 | 735
Autosomal recessive predisposition 12 | 1,442
Intellectual disability 12 | 1,016
Leukemia, Myelocytic, Acute 12 | 120
Schizophrenia 12 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
mucosa-associated lymphoid tissue lymphoma 12 | 484
nasopharyngeal carcinoma 12 | 1,058
pancreatic carcinoma 12 | 562
Asthma 11 | 385
Bipolar Disorder 11 | 666
Leukemia, Myeloid, Acute 11 | 105
active Crohn's disease 11 | 922
non primary Sjogren syndrome sicca 11 | 891
Acquired metabolic disease 10 | 336
Alzheimer's disease 10 | 658
Arthritis 10 | 290
Arthritis, Rheumatoid 10 | 174
Breast Neoplasms 10 | 445
Chronic Lymphocytic Leukemia 10 | 262
Dull intelligence 10 | 645
Low intelligence 10 | 645
Mammary Neoplasms 10 | 425
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
Duchenne muscular dystrophy 9 | 601
Cerebrovascular disease 8 | 238
Depressive disorder 8 | 409
Lymphoid leukemia 8 | 160
Muscle hypotonia 8 | 571
Prostatic Neoplasms 8 | 495
Splenomegaly 8 | 190
chronic lymphosyte leukemia 8 | 204
progressive supranuclear palsy 8 | 676
spina bifida 8 | 1,074
aldosterone-producing adenoma 7 | 665
nephrosclerosis 7 | 333

Tissue

Digestive Tract 166 | 17,369
Endocrine System 166 | 18,159
Female tissues 166 | 17,400
Blood and immune system 165 | 16,909
Skin and soft tissues 164 | 17,230
Nervous System 163 | 16,725
Liver and Pancreas 162 | 16,750
Respiratory system 162 | 16,393
Male tissues 160 | 17,142
Urinary Tract 159 | 16,678
Cardiovascular System 156 | 15,192

Target Family

Non-IDG 87 | 12,091
Enzyme 27 | 4,145
Transcription Factor 22 | 1,400
GPCR 12 | 408
Kinase 12 | 634
Epigenetic 7 | 242
Transporter 4 | 473
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

GWAS Trait

Monocyte percentage of white c... 173 | 173
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149
T-complex protein 11 homolog TCP11 Tbio Non-IDG -1.26152 18.0 80
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
Putative peripheral benzodiazepine receptor-related protein TSPO Tchem Non-IDG -3.08695 2284.2 212
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.33153 18.0 188
Polycomb group RING finger protein 3 PCGF3 Tdark Non-IDG -0.48328 1.97 115
Major facilitator superfamily domain-containing protein 2B MFSD2B Tdark Non-IDG -0.40512 1.19 80
Suppressor of tumorigenicity 20 protein ST20 Tdark Non-IDG -1.66163 0.71 0