Development Level

Tbio 114 | 11,445
Tchem 30 | 1,598
Tdark 26 | 6,588
Tclin 13 | 613

Collection

Kinase: IDG Consortium (Target... 4 | 125
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 9 | 979
decreased mean corpuscular vol... 4 | 79
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased hemoglobin content 3 | 68
hyperactivity 3 | 148
increased mean corpuscular hem... 3 | 96
increased startle reflex 3 | 112
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased hematocrit 2 | 46
decreased mean corpuscular hem... 2 | 50
enlarged heart 2 | 210
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 76
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 36
short tibia 2 | 97
small superior vagus ganglion 2 | 74
abnormal QT variability 1 | 10
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal lung morphology 1 | 26
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pancreas morphology 1 | 13
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal stomach morphology 1 | 10
decreased IgG1 level 1 | 8
decreased IgG2b level 1 | 4
decreased NK T cell number 1 | 2
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating creatine... 1 | 4
decreased circulating free fat... 1 | 31
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased granulocyte number 1 | 6
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased B cell number 1 | 9
increased basophil cell number 1 | 7
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prolonged QRS complex duration 1 | 8
thrombocytopenia 1 | 56
tremors 1 | 39
urinary bladder obstruction 1 | 4

Disease

Carcinoma 115 | 11,493
osteosarcoma 101 | 7,950
ovarian cancer 99 | 8,520
medulloblastoma, large-cell 74 | 6,241
glioblastoma 72 | 5,792
psoriasis 72 | 6,694
lung cancer 60 | 4,740
invasive ductal carcinoma 53 | 2,951
Cancer 52 | 2,499
Breast cancer 51 | 3,578
atypical teratoid / rhabdoid tumor 51 | 5,112
Astrocytoma, Pilocytic 48 | 3,081
group 3 medulloblastoma 48 | 4,104
ependymoma 46 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,291
lung carcinoma 46 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 45 | 2,989
tuberculosis 45 | 2,010
adult high grade glioma 44 | 3,801
malignant mesothelioma 44 | 3,232
non-small cell lung cancer 44 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 43 | 2,955
interstitial cystitis 42 | 2,312
lung adenocarcinoma 42 | 2,716
pancreatic cancer 40 | 2,398
ulcerative colitis 36 | 1,819
pituitary cancer 35 | 1,972
primitive neuroectodermal tumor 32 | 3,035
ductal carcinoma in situ 31 | 1,745
cystic fibrosis 30 | 1,696
oligodendroglioma 30 | 2,850
subependymal giant cell astrocytoma 30 | 2,287
astrocytic glioma 29 | 2,597
breast carcinoma 29 | 1,638
colon cancer 25 | 1,478
diabetes mellitus 24 | 1,728
primary pancreatic ductal adenocarcinoma 24 | 1,109
group 4 medulloblastoma 23 | 1,855
juvenile dermatomyositis 23 | 1,187
Kidney cancer 22 | 2,613
Rheumatoid arthritis 22 | 1,191
Multiple myeloma 21 | 1,332
astrocytoma 20 | 1,146
adrenocortical carcinoma 19 | 1,428
Pick disease 18 | 1,894
acute quadriplegic myopathy 18 | 1,158
Crohn's disease 17 | 321
Waldenstrons macroglobulinemia 17 | 765
primary Sjogren syndrome 17 | 735
Schizophrenia 16 | 1,160
cutaneous lupus erythematosus 16 | 1,057
Autosomal recessive predisposition 15 | 1,442
Liver Cirrhosis, Experimental 15 | 769
Duchenne muscular dystrophy 14 | 601
active ulcerative colitis 14 | 764
dermatomyositis 14 | 966
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Melanoma 13 | 711
Multiple Sclerosis 13 | 540
esophageal adenocarcinoma 13 | 737
nasopharyngeal carcinoma 13 | 1,058
Alzheimer's disease 12 | 658
Arthritis 12 | 290
Breast Neoplasms 12 | 445
Mammary Neoplasms 12 | 425
gastric carcinoma 12 | 807
hepatocellular carcinoma 12 | 547
Anemia 11 | 365
Atherosclerosis 11 | 291
acute myeloid leukemia 11 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
Atopic dermatitis 10 | 952
Cerebrovascular disease 10 | 238
Depressive disorder 10 | 409
Intellectual disability 10 | 1,016
Leukemia, Myelocytic, Acute 10 | 120
Liver cancer 10 | 604
Lymphoid leukemia 10 | 160
Splenomegaly 10 | 190
active Crohn's disease 10 | 922
spina bifida 10 | 1,074
Arthritis, Rheumatoid 9 | 174
Bipolar Disorder 9 | 666
Cognitive delay 9 | 608
Dull intelligence 9 | 645
Global developmental delay 9 | 608
Kidney disease 9 | 430
Leukemia, Myeloid, Acute 9 | 105
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental and motor retardation 9 | 608
Mental deficiency 9 | 645
Muscle hypotonia 9 | 571
Obesity 9 | 678
Poor school performance 9 | 645
Renal Cell Carcinoma 9 | 214
gastric cancer 9 | 459
mucosa-associated lymphoid tissue lymphoma 9 | 484
periodontitis 9 | 293
Immune system cancer 8 | 140

Tissue

Skin and soft tissues 175 | 17,230
Endocrine System 174 | 18,159
Digestive Tract 172 | 17,369
Female tissues 172 | 17,400
Liver and Pancreas 172 | 16,750
Blood and immune system 171 | 16,909
Male tissues 171 | 17,142
Urinary Tract 170 | 16,678
Nervous System 168 | 16,725
Respiratory system 168 | 16,393
Cardiovascular System 156 | 15,192

Target Family

Non-IDG 96 | 12,091
Enzyme 29 | 4,145
Transcription Factor 18 | 1,400
Kinase 17 | 634
GPCR 11 | 408
Transporter 6 | 473
Epigenetic 4 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GWAS Trait

Monocyte count 183 | 183
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WW domain binding protein 1-like WBP1L Tdark Non-IDG -0.60041 2.79 27
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149
Prostaglandin reductase 1 PTGR1 Tbio Enzyme -1.28265 22.7 156
Tubulin delta chain TUBD1 Tbio Non-IDG -1.28681 18.5 57
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Putative peripheral benzodiazepine receptor-related protein TSPO Tchem Non-IDG -3.08695 2284.2 212
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37
Selenide, water dikinase 2 SEPHS2 Tdark Enzyme -1.42671 25.3 0
Homeobox protein CDX-2 CDX2 Tbio Transcription Factor -2.91273 837.0 699