Development Level

Tbio 56 | 11,445
Tdark 13 | 6,588
Tchem 8 | 1,598
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 5 | 499
decreased body weight 2 | 161
decreased circulating serum al... 2 | 82
decreased heart left ventricle... 2 | 28
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal limb bud morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
absent startle reflex 1 | 24
aorta stenosis 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged spleen 1 | 41
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased heart rate 1 | 23
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged PQ interval 1 | 5
prolonged ST segment 1 | 36
small kidney 1 | 16
small testis 1 | 58
thick ventricular wall 1 | 7
thin ventricular wall 1 | 24

Disease

Carcinoma 66 | 11,493
osteosarcoma 43 | 7,950
ovarian cancer 42 | 8,520
atypical teratoid / rhabdoid tumor 37 | 5,112
medulloblastoma, large-cell 35 | 6,241
glioblastoma 33 | 5,792
psoriasis 31 | 6,694
adult high grade glioma 29 | 3,801
ependymoma 29 | 4,679
lung cancer 27 | 4,740
primitive neuroectodermal tumor 25 | 3,035
Kidney cancer 24 | 2,613
invasive ductal carcinoma 24 | 2,951
Astrocytoma, Pilocytic 23 | 3,081
group 3 medulloblastoma 23 | 4,104
lung carcinoma 23 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
malignant mesothelioma 20 | 3,232
Breast cancer 19 | 3,578
oligodendroglioma 19 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
astrocytic glioma 16 | 2,597
lung adenocarcinoma 16 | 2,716
subependymal giant cell astrocytoma 16 | 2,287
non-small cell lung cancer 15 | 2,890
pancreatic cancer 15 | 2,398
Cancer 14 | 2,499
tuberculosis 14 | 2,010
cystic fibrosis 12 | 1,696
interstitial cystitis 12 | 2,312
Migraine 11 | 83
Pick disease 11 | 1,894
ductal carcinoma in situ 11 | 1,745
ulcerative colitis 11 | 1,819
Schizophrenia 10 | 1,160
adrenocortical carcinoma 10 | 1,428
primary pancreatic ductal adenocarcinoma 10 | 1,109
group 4 medulloblastoma 9 | 1,855
Multiple Sclerosis 8 | 540
Rheumatoid arthritis 8 | 1,191
astrocytoma 8 | 1,146
colon cancer 8 | 1,478
juvenile dermatomyositis 8 | 1,187
posterior fossa group A ependymoma 8 | 468
Asthma 7 | 385
Endometriosis 7 | 540
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
pituitary cancer 7 | 1,972
Atherosclerosis 6 | 291
Chronic obstructive pulmonary disease 6 | 184
Liver cancer 6 | 604
Melanoma 6 | 711
acute quadriplegic myopathy 6 | 1,158
diabetes mellitus 6 | 1,728
gastric carcinoma 6 | 807
pediatric high grade glioma 6 | 1,064
Alzheimer's disease 5 | 658
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Common Migraine 5 | 7
Coronary artery disease 5 | 268
Intellectual disability 5 | 1,016
Liver disease 5 | 237
Migraine Disorders 5 | 76
Migraine without Aura 5 | 11
Osteoporosis 5 | 363
active ulcerative colitis 5 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
breast carcinoma 5 | 1,638
cutaneous lupus erythematosus 5 | 1,057
dermatomyositis 5 | 966
interstitial lung disease 5 | 298
medulloblastoma 5 | 720
nasopharyngeal carcinoma 5 | 1,058
primary Sjogren syndrome 5 | 735
spina bifida 5 | 1,074
Autistic Disorder 4 | 364
Cerebrovascular disease 4 | 238
Crohn's disease 4 | 321
Depressive disorder 4 | 409
Duchenne muscular dystrophy 4 | 601
Dull intelligence 4 | 645
Epilepsy 4 | 792
Hypertension 4 | 396
Kidney disease 4 | 430
Low intelligence 4 | 645
Major Depressive Disorder 4 | 301
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Muscle Weakness 4 | 170
Poor school performance 4 | 645
Prostatic Neoplasms 4 | 495
Proteinuria 4 | 144
Pulmonary emphysema 4 | 48
Seizures 4 | 596
active Crohn's disease 4 | 922
mucosa-associated lymphoid tissue lymphoma 4 | 484
sarcoidosis 4 | 370
acute myeloid leukemia 3 | 783

Tissue

Endocrine System 79 | 18,159
Digestive Tract 78 | 17,369
Male tissues 77 | 17,142
Skin and soft tissues 76 | 17,230
Female tissues 75 | 17,400
Nervous System 75 | 16,725
Blood and immune system 73 | 16,909
Liver and Pancreas 73 | 16,750
Respiratory system 72 | 16,393
Urinary Tract 69 | 16,678
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 43 | 12,091
Enzyme 17 | 4,145
Transcription Factor 6 | 1,400
Epigenetic 3 | 242
Ion Channel 3 | 344
Kinase 3 | 634
GPCR 2 | 408
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38
Transporter 1 | 473

GWAS Trait

Migraine 81 | 81
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctophilin-3 JPH3 Tbio Non-IDG -1.51901 34.8 165
One cut domain family member 2 ONECUT2 Tbio Transcription Factor -2.25163 169.5 107
SKI family transcriptional corepressor 2 SKOR2 Tbio Non-IDG -0.52843 4.42 59
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 ASAP1 Tbio Non-IDG -1.76454 62.6 183
Tyrosine-protein kinase BAZ1B BAZ1B Tbio Epigenetic -1.45627 32.0 155
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.12274 13.0 86
Cerebral cavernous malformations 2 protein-like CCM2L Tdark Non-IDG -0.06695 1.24 54
Sodium channel protein type 11 subunit alpha SCN11A Tclin Ion Channel -2.46568 276.3 60
FERM, ARHGEF and pleckstrin domain-containing protein 1 FARP1 Tbio Non-IDG -1.56544 38.3 153
Kinase suppressor of Ras 2 KSR2 Tbio Kinase -0.90433 8.77 280