Development Level

Tbio 21 | 11,445
Tchem 9 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal seminal vesicle morph... 2 | 114
decreased circulating LDL chol... 2 | 38
hyperactivity 2 | 148
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate 1 | 23
increased lean body mass 1 | 172
small testis 1 | 58

Disease

Carcinoma 25 | 11,493
Metabolic syndrome X 25 | 52
psoriasis 17 | 6,694
diabetes mellitus 16 | 1,728
osteosarcoma 16 | 7,950
ovarian cancer 15 | 8,520
Cardiovascular system disease 14 | 246
Type 2 diabetes mellitus 13 | 272
glioblastoma 13 | 5,792
ependymoma 12 | 4,679
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
Obesity 11 | 678
primitive neuroectodermal tumor 11 | 3,035
Lipid metabolism disorder 10 | 114
atypical teratoid / rhabdoid tumor 10 | 5,112
malignant mesothelioma 10 | 3,232
Acquired metabolic disease 9 | 336
Astrocytoma, Pilocytic 9 | 3,081
oligodendroglioma 9 | 2,850
Atherosclerosis 8 | 291
Breast cancer 8 | 3,578
Schizophrenia 8 | 1,160
adult high grade glioma 8 | 3,801
invasive ductal carcinoma 8 | 2,951
Coronary artery disease 7 | 268
Kidney cancer 7 | 2,613
astrocytic glioma 7 | 2,597
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Vascular disease 6 | 319
lung adenocarcinoma 6 | 2,716
Colorectal Neoplasms 5 | 243
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
Hyperglycemia 5 | 137
Hypertriglyceridemia 5 | 17
active ulcerative colitis 5 | 764
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
Autosomal recessive predisposition 4 | 1,442
Hypercholesterolemia 4 | 44
Hypercholesterolemia, Familial 4 | 23
Hyperlipidemia 4 | 43
Hyperlipoproteinemia Type II 4 | 12
Hypertension 4 | 396
Kidney disease 4 | 430
Rheumatoid arthritis 4 | 1,191
active Crohn's disease 4 | 922
astrocytoma 4 | 1,146
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Alcoholic Intoxication, Chronic 3 | 289
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Cancer 3 | 2,499
Cardiovascular Diseases 3 | 59
Chemical and Drug Induced Liver Injury 3 | 195
Diabetes Mellitus, Noninsulin-Dependent 3 | 31
Dyslipidemias 3 | 27
Fatty liver disease 3 | 103
Gestational diabetes 3 | 26
Hypercholesterolemia, Autosomal Dominant, Type B 3 | 5
Hyperinsulinism 3 | 133
Hyperlipidemias 3 | 17
Hypertensive disease 3 | 292
Liver Cirrhosis, Experimental 3 | 769
Melanoma 3 | 711
Myocardial Infarction 3 | 151
Pediatric Obesity 3 | 4
Serum cholesterol raised 3 | 22
Xanthomatosis 3 | 12
adrenocortical carcinoma 3 | 1,428
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
fibroadenoma 3 | 559
mucosa-associated lymphoid tissue lymphoma 3 | 484
non primary Sjogren syndrome sicca 3 | 891
pediatric high grade glioma 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Attention deficit hyperactivity disorder 2 | 278
Epilepsy 2 | 792
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Seizures 2 | 596
Small nose 2 | 132
Waldenstrons macroglobulinemia 2 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic lymphosyte leukemia 2 | 204
colon cancer 2 | 1,478
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058

Tissue

Endocrine System 34 | 18,159
Digestive Tract 33 | 17,369
Female tissues 33 | 17,400
Skin and soft tissues 33 | 17,230
Liver and Pancreas 32 | 16,750
Blood and immune system 31 | 16,909
Male tissues 31 | 17,142
Respiratory system 31 | 16,393
Urinary Tract 31 | 16,678
Cardiovascular System 30 | 15,192
Nervous System 30 | 16,725

Target Family

Non-IDG 13 | 12,091
Enzyme 12 | 4,145
Kinase 4 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408
Nuclear Receptor 1 | 48
Transporter 1 | 473

GWAS Trait

Metabolic syndrome 34 | 34
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Fatty acid desaturase 2 FADS2 Tbio Enzyme -2.55411 349.6 135
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase PKMYT1 Tchem Kinase -1.27237 19.2 364
Probable E3 ubiquitin-protein ligase HECTD4 HECTD4 Tbio Enzyme -1.02570 11.0 0
Transmembrane protein 258 TMEM258 Tdark Non-IDG -0.35218 2.02 6
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.58826 425.0 481
Adenylate kinase isoenzyme 1 AK1 Tbio Kinase -2.37718 230.1 422
Protein shisa-9 SHISA9 Tbio Non-IDG -0.85274 7.49 66
Melatonin receptor type 1B MTNR1B Tclin GPCR -2.01297 100.6 222