Development Level

Tbio 190 | 11,651
Tdark 37 | 6,593
Tchem 16 | 1,388
Tclin 10 | 612

Collection

RFA-RM-18-021 6 | 328
GPCR: IDG Consortium (Targets) 3 | 126
Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 17 | 979
preweaning lethality, incomple... 10 | 499
decreased total body fat amoun... 7 | 207
decreased vertical activity 7 | 208
thrombocytopenia 6 | 56
decreased body weight 5 | 161
decreased circulating choleste... 5 | 93
decreased leukocyte cell numbe... 5 | 73
decreased mean corpuscular hem... 5 | 50
decreased threshold for audito... 5 | 26
enlarged heart 5 | 210
increased lean body mass 5 | 172
abnormal behavior 4 | 298
abnormal bone structure 4 | 187
cardiovascular system phenotyp... 4 | 36
decreased bone mineral content 4 | 151
decreased circulating glucose ... 4 | 126
decreased mean corpuscular vol... 4 | 79
decreased prepulse inhibition 4 | 82
embryonic lethality prior to t... 4 | 278
hyperactivity 4 | 148
improved glucose tolerance 4 | 79
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
abnormal sleep behavior 3 | 70
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 68
decreased erythrocyte cell num... 3 | 62
decreased hemoglobin content 3 | 68
impaired glucose tolerance 3 | 75
increased bone mineral content 3 | 108
increased bone mineral density 3 | 72
increased heart weight 3 | 62
increased leukocyte cell numbe... 3 | 47
increased lymphocyte cell numb... 3 | 32
increased mean corpuscular hem... 3 | 96
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
abnormal behavioral response t... 2 | 66
abnormal coat appearance 2 | 31
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
abnormal testis morphology 2 | 43
abnormal vitreous body morphol... 2 | 10
decreased body length 2 | 101
decreased circulating magnesiu... 2 | 13
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased mean corpuscular hem... 2 | 31
decreased neutrophil cell numb... 2 | 42
decreased red blood cell distr... 2 | 41
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
enlarged spleen 2 | 41
hemorrhage 2 | 23
hypoactivity 2 | 132
increased blood urea nitrogen ... 2 | 48
increased circulating bilirubi... 2 | 16
increased circulating glucose ... 2 | 24
increased circulating iron lev... 2 | 30
increased heart rate 2 | 23
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
male infertility 2 | 123
short tibia 2 | 97
shortened RR interval 2 | 17
small testis 2 | 58
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
convulsive seizures 1 | 13
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating serum al... 1 | 82
decreased lean body mass 1 | 135
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 180 | 11,493
osteosarcoma 146 | 7,950
ovarian cancer 141 | 8,520
medulloblastoma, large-cell 113 | 6,241
glioblastoma 105 | 5,792
atypical teratoid / rhabdoid tumor 92 | 5,112
psoriasis 92 | 6,694
ependymoma 82 | 4,679
lung cancer 81 | 4,740
adult high grade glioma 74 | 3,801
group 3 medulloblastoma 69 | 4,104
Breast cancer 64 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 64 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 62 | 2,989
Astrocytoma, Pilocytic 60 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 58 | 3,291
non-small cell lung cancer 57 | 2,890
primitive neuroectodermal tumor 57 | 3,035
Kidney cancer 55 | 2,613
malignant mesothelioma 55 | 3,232
lung carcinoma 54 | 2,843
pancreatic cancer 52 | 2,398
subependymal giant cell astrocytoma 52 | 2,287
oligodendroglioma 50 | 2,850
lung adenocarcinoma 48 | 2,716
interstitial cystitis 47 | 2,312
astrocytic glioma 46 | 2,597
Cancer 45 | 2,499
invasive ductal carcinoma 45 | 2,951
ulcerative colitis 42 | 1,819
tuberculosis 41 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 36 | 1,962
pituitary cancer 36 | 1,972
group 4 medulloblastoma 35 | 1,855
Pick disease 33 | 1,894
spina bifida 29 | 1,074
ductal carcinoma in situ 28 | 1,745
cystic fibrosis 27 | 1,696
Rheumatoid arthritis 26 | 1,191
colon cancer 26 | 1,478
diabetes mellitus 25 | 1,728
esophageal adenocarcinoma 24 | 737
Autosomal recessive predisposition 23 | 1,442
Multiple myeloma 23 | 1,332
cutaneous lupus erythematosus 23 | 1,057
gastric carcinoma 22 | 807
juvenile dermatomyositis 22 | 1,187
primary pancreatic ductal adenocarcinoma 22 | 1,109
Waldenstrons macroglobulinemia 21 | 765
breast carcinoma 21 | 1,638
pancreatic carcinoma 21 | 562
Schizophrenia 20 | 1,160
acute myeloid leukemia 20 | 783
primary Sjogren syndrome 19 | 735
Liver Cirrhosis, Experimental 18 | 769
active Crohn's disease 18 | 922
acute quadriplegic myopathy 18 | 1,158
Hemolytic anemia 17 | 77
Thrombocytopenia 17 | 197
active ulcerative colitis 17 | 764
adrenocortical carcinoma 17 | 1,428
dermatomyositis 17 | 966
pediatric high grade glioma 16 | 1,064
Epilepsy 15 | 792
astrocytoma 15 | 1,146
gastric cancer 15 | 459
mucosa-associated lymphoid tissue lymphoma 14 | 484
nasopharyngeal carcinoma 14 | 1,058
Atopic dermatitis 13 | 952
Intellectual disability 13 | 1,016
Multiple Sclerosis 13 | 540
Alzheimer's disease 12 | 658
Liver cancer 12 | 604
posterior fossa group B ependymoma 12 | 416
Cardiovascular system disease 11 | 246
Crohn's disease 11 | 321
aldosterone-producing adenoma 11 | 665
sonic hedgehog group medulloblastoma 11 | 467
Anemia 10 | 365
Atherosclerosis 10 | 291
Chronic Lymphocytic Leukemia 10 | 262
Coronary artery disease 10 | 268
Heart disease 10 | 306
Obesity 10 | 678
Prostatic Neoplasms 10 | 495
Seizures 10 | 596
Type 2 diabetes mellitus 10 | 272
hepatocellular carcinoma 10 | 547
medulloblastoma 10 | 720
progressive supranuclear palsy 10 | 676
Bipolar Disorder 9 | 666
Cerebrovascular disease 9 | 238
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Major Depressive Disorder 9 | 301
Melanoma 9 | 711
Mental and motor retardation 9 | 608
chronic lymphosyte leukemia 9 | 204
chronic rhinosinusitis 9 | 512
non primary Sjogren syndrome sicca 9 | 891

Tissue

Digestive Tract 245 | 17,369
Endocrine System 245 | 18,159
Male tissues 245 | 17,142
Blood and immune system 243 | 16,909
Respiratory system 243 | 16,393
Skin and soft tissues 243 | 17,230
Female tissues 242 | 17,400
Urinary Tract 241 | 16,678
Liver and Pancreas 240 | 16,750
Nervous System 237 | 16,725
Cardiovascular System 230 | 15,192

Target Family

Non-IDG 156 | 12,091
Enzyme 47 | 4,145
Transcription Factor 20 | 1,400
Kinase 8 | 634
GPCR 6 | 408
Transporter 6 | 473
Epigenetic 4 | 242
Ion Channel 4 | 344
TF/Epigenetic 2 | 38

GWAS Trait

Mean platelet volume 253 | 253
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C4b-binding protein alpha chain C4BPA Tbio Non-IDG -2.43425 244.7 172
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83
Protein MRVI1 MRVI1 Tbio Non-IDG -1.40400 26.2 22
Programmed cell death protein 10 PDCD10 Tbio Non-IDG -1.63894 37.2 185
Arylsulfatase A ARSA Tbio Enzyme -2.50334 319.0 337
REST corepressor 1 RCOR1 Tbio Transcription Factor -1.96775 81.2 0
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Outer dense fiber protein 3 ODF3 Tdark Non-IDG -0.68499 4.08 89
Ankyrin repeat and death domain-containing protein 1A ANKDD1A Tdark Non-IDG 1.04 0.05 81
Proline and serine-rich protein 2 PROSER2 Tdark Non-IDG 0.78 0.13 43