Development Level

Tbio 197 | 11,651
Tdark 48 | 6,593
Tchem 27 | 1,388
Tclin 11 | 612

Collection

RFA-RM-18-021 2 | 328
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 24 | 979
abnormal embryo size 7 | 220
increased mean corpuscular hem... 7 | 96
decreased leukocyte cell numbe... 6 | 73
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 6 | 278
increased mean corpuscular vol... 6 | 92
preweaning lethality, incomple... 6 | 499
abnormal behavior 5 | 298
decreased bone mineral content 5 | 151
decreased bone mineral density 5 | 126
decreased circulating glucose ... 5 | 126
prenatal lethality prior to he... 5 | 87
abnormal bone structure 4 | 187
abnormal eye morphology 4 | 68
abnormal lens morphology 4 | 81
cataract 4 | 92
decreased body length 4 | 101
decreased erythrocyte cell num... 4 | 62
decreased total body fat amoun... 4 | 207
enlarged heart 4 | 210
increased circulating HDL chol... 4 | 80
male infertility 4 | 123
abnormal behavioral response t... 3 | 66
abnormal cornea morphology 3 | 31
abnormal heart morphology 3 | 162
decreased circulating choleste... 3 | 93
decreased circulating total pr... 3 | 49
decreased startle reflex 3 | 75
embryonic growth retardation 3 | 106
increased bone mineral density 3 | 72
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
increased hematocrit 3 | 46
increased mean platelet volume 3 | 45
pallor 3 | 34
prenatal lethality 3 | 28
thrombocytopenia 3 | 56
abnormal kidney morphology 2 | 65
abnormal motor capabilities-co... 2 | 5
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal tail morphology 2 | 25
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
decreased total retina thickne... 2 | 17
decreased vertical activity 2 | 208
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased bone mineral content 2 | 108
increased circulating bilirubi... 2 | 16
increased circulating fructosa... 2 | 13
increased circulating glucose ... 2 | 24
increased circulating iron lev... 2 | 30
increased circulating potassiu... 2 | 29
increased grip strength 2 | 41
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
increased prepulse inhibition 2 | 32
increased startle reflex 2 | 112
mydriasis 2 | 6
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
thrombocytosis 2 | 27
tremors 2 | 39
abnormal craniofacial morpholo... 1 | 33
abnormal gait 1 | 69
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
increased body length 1 | 32
increased circulating aspartat... 1 | 15
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased red blood cell distr... 1 | 34
long tibia 1 | 25

Disease

Carcinoma 180 | 11,493
osteosarcoma 164 | 7,950
ovarian cancer 149 | 8,520
psoriasis 121 | 6,694
medulloblastoma, large-cell 102 | 6,241
glioblastoma 97 | 5,792
lung cancer 97 | 4,740
atypical teratoid / rhabdoid tumor 90 | 5,112
ependymoma 82 | 4,679
Breast cancer 79 | 3,578
group 3 medulloblastoma 73 | 4,104
Cancer 69 | 2,499
adult high grade glioma 64 | 3,801
malignant mesothelioma 62 | 3,232
non-small cell lung cancer 59 | 2,890
invasive ductal carcinoma 58 | 2,951
lung adenocarcinoma 56 | 2,716
tuberculosis 52 | 2,010
intraductal papillary-mucinous neoplasm (IPMN) 51 | 3,291
Kidney cancer 49 | 2,613
pancreatic cancer 49 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,989
primitive neuroectodermal tumor 48 | 3,035
lung carcinoma 47 | 2,843
Astrocytoma, Pilocytic 46 | 3,081
subependymal giant cell astrocytoma 44 | 2,287
ductal carcinoma in situ 40 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 40 | 1,962
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,955
interstitial cystitis 35 | 2,312
breast carcinoma 34 | 1,638
diabetes mellitus 33 | 1,728
Rheumatoid arthritis 32 | 1,191
dermatomyositis 32 | 966
group 4 medulloblastoma 31 | 1,855
oligodendroglioma 31 | 2,850
pituitary cancer 30 | 1,972
Peripheral vascular disease 29 | 87
colon cancer 29 | 1,478
cystic fibrosis 29 | 1,696
juvenile dermatomyositis 29 | 1,187
ulcerative colitis 29 | 1,819
Pick disease 28 | 1,894
Autosomal recessive predisposition 27 | 1,442
Anemia 26 | 365
astrocytic glioma 25 | 2,597
astrocytoma 25 | 1,146
Waldenstrons macroglobulinemia 24 | 765
Atopic dermatitis 23 | 952
acute myeloid leukemia 22 | 783
cutaneous lupus erythematosus 22 | 1,057
acute quadriplegic myopathy 21 | 1,158
pediatric high grade glioma 21 | 1,064
adrenocortical carcinoma 20 | 1,428
Multiple myeloma 19 | 1,332
Schizophrenia 19 | 1,160
primary Sjogren syndrome 19 | 735
spina bifida 19 | 1,074
Hemolytic anemia 18 | 77
pancreatic carcinoma 18 | 562
Obesity 17 | 678
esophageal adenocarcinoma 17 | 737
nasopharyngeal carcinoma 17 | 1,058
mucosa-associated lymphoid tissue lymphoma 16 | 484
non primary Sjogren syndrome sicca 16 | 891
Crohn's disease 15 | 321
Intellectual disability 15 | 1,016
Kidney disease 15 | 430
Thalassemia 15 | 53
Type 2 diabetes mellitus 15 | 272
primary pancreatic ductal adenocarcinoma 15 | 1,109
Duchenne muscular dystrophy 14 | 601
Hepatomegaly 14 | 285
Prostatic Neoplasms 14 | 495
hepatocellular carcinoma 14 | 547
Breast Neoplasms 13 | 445
Chronic Lymphocytic Leukemia 13 | 262
active ulcerative colitis 13 | 764
gastric cancer 13 | 459
Disease Models, Animal 12 | 155
Leukemia, Myelocytic, Acute 12 | 120
Liver cancer 12 | 604
Mammary Neoplasms 12 | 425
Polycystic ovary syndrome 12 | 360
atypical teratoid/rhabdoid tumor 12 | 357
chronic rhinosinusitis 12 | 512
gastric carcinoma 12 | 807
progressive supranuclear palsy 12 | 676
Acquired metabolic disease 11 | 336
Endometriosis 11 | 540
Leukemia, Myeloid, Acute 11 | 105
Multiple Sclerosis 11 | 540
Vascular disease 11 | 319
sonic hedgehog group medulloblastoma 11 | 467
Dull intelligence 10 | 645
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
Splenomegaly 10 | 190

Tissue

Endocrine System 274 | 18,159
Blood and immune system 271 | 16,909
Female tissues 271 | 17,400
Skin and soft tissues 268 | 17,230
Digestive Tract 267 | 17,369
Liver and Pancreas 267 | 16,750
Nervous System 267 | 16,725
Male tissues 264 | 17,142
Urinary Tract 263 | 16,678
Respiratory system 258 | 16,393
Cardiovascular System 250 | 15,192

Target Family

Non-IDG 149 | 12,091
Enzyme 53 | 4,145
Transcription Factor 34 | 1,400
Transporter 13 | 473
Kinase 11 | 634
Epigenetic 7 | 242
oGPCR 5 | 421
Ion Channel 4 | 344
TF/Epigenetic 3 | 38
GPCR 2 | 408
Nuclear Receptor 2 | 48

GWAS Trait

Mean corpuscular volume 283 | 283
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromatin assembly factor 1 subunit A CHAF1A Tbio Non-IDG -1.60312 40.7 157
Nuclear receptor coactivator 4 NCOA4 Tbio Non-IDG -2.20245 136.0 283
Diphosphoinositol polyphosphate phosphohydrolase 1 NUDT3 Tbio Enzyme -2.01736 105.3 40
Nuclear-interacting partner of ALK ZC3HC1 Tbio Non-IDG -2.13812 136.0 171
Pre-mRNA-splicing factor SYF2 SYF2 Tbio Non-IDG -1.04825 13.2 124
Protein inturned INTU Tbio Non-IDG -1.76006 53.9 56
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.52487 33.2 60
Synaptic vesicle glycoprotein 2C SV2C Tbio Non-IDG -1.38055 21.0 85
Neuritin-like protein NRN1L Tdark Non-IDG 0.70 0.20 71
WD repeat domain phosphoinositide-interacting protein 2 WIPI2 Tbio Non-IDG -1.16004 13.0 195