Development Level

Tbio 57 | 11,651
Tdark 16 | 6,593
Tchem 6 | 1,388
Tclin 6 | 612

IMPC Phenotype

decreased bone mineral density 3 | 126
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased bone mineral content 2 | 151
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal outer ear morphology 1 | 3
abnormal placenta size 1 | 20
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
anophthalmia 1 | 33
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
long tibia 1 | 25
male infertility 1 | 123
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 60 | 11,493
osteosarcoma 49 | 7,950
psoriasis 39 | 6,694
ovarian cancer 38 | 8,520
medulloblastoma, large-cell 35 | 6,241
glioblastoma 29 | 5,792
lung cancer 29 | 4,740
ependymoma 28 | 4,679
atypical teratoid / rhabdoid tumor 23 | 5,112
Breast cancer 21 | 3,578
adult high grade glioma 21 | 3,801
group 3 medulloblastoma 20 | 4,104
invasive ductal carcinoma 17 | 2,951
malignant mesothelioma 17 | 3,232
Anemia 16 | 365
Astrocytoma, Pilocytic 16 | 3,081
pancreatic cancer 16 | 2,398
tuberculosis 16 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung carcinoma 15 | 2,843
non-small cell lung cancer 15 | 2,890
primitive neuroectodermal tumor 14 | 3,035
Peripheral vascular disease 13 | 87
Thalassemia 13 | 53
lung adenocarcinoma 13 | 2,716
ulcerative colitis 13 | 1,819
Kidney cancer 12 | 2,613
ductal carcinoma in situ 12 | 1,745
oligodendroglioma 12 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Autosomal recessive predisposition 11 | 1,442
Cancer 11 | 2,499
Pick disease 11 | 1,894
Hemolytic anemia 10 | 77
breast carcinoma 10 | 1,638
cystic fibrosis 10 | 1,696
mucosa-associated lymphoid tissue lymphoma 10 | 484
subependymal giant cell astrocytoma 10 | 2,287
Atopic dermatitis 9 | 952
Splenomegaly 9 | 190
astrocytic glioma 9 | 2,597
diabetes mellitus 9 | 1,728
esophageal adenocarcinoma 9 | 737
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
spina bifida 9 | 1,074
Congenital hemolytic anemia 8 | 32
Duchenne muscular dystrophy 8 | 601
Liver disease 8 | 237
Type 2 diabetes mellitus 8 | 272
astrocytoma 8 | 1,146
dermatomyositis 8 | 966
interstitial cystitis 8 | 2,312
pituitary cancer 8 | 1,972
Hemochromatosis 7 | 54
Hepatomegaly 7 | 285
Icterus 7 | 82
Rheumatoid arthritis 7 | 1,191
acute quadriplegic myopathy 7 | 1,158
colon cancer 7 | 1,478
group 4 medulloblastoma 7 | 1,855
juvenile dermatomyositis 7 | 1,187
pancreatic carcinoma 7 | 562
Obesity 6 | 678
Reticulocytosis 6 | 20
Sickle Cell Anemia 6 | 53
Waldenstrons macroglobulinemia 6 | 765
acute myeloid leukemia 6 | 783
adrenocortical carcinoma 6 | 1,428
hepatocellular carcinoma 6 | 547
Alzheimer's disease 5 | 658
Anemia, Hemolytic 5 | 55
Cardiovascular system disease 5 | 246
Chronic Lymphocytic Leukemia 5 | 262
Iron deficiency anemia 5 | 12
Liver Cirrhosis, Experimental 5 | 769
Malaria 5 | 160
Schizophrenia 5 | 1,160
Vascular disease 5 | 319
active ulcerative colitis 5 | 764
aldosterone-producing adenoma 5 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
gastric carcinoma 5 | 807
nasopharyngeal carcinoma 5 | 1,058
pediatric high grade glioma 5 | 1,064
Colorectal Neoplasms 4 | 243
Coronary artery disease 4 | 268
Crohn's disease 4 | 321
Down syndrome 4 | 499
Increased bilirubin level (finding) 4 | 18
Liver cancer 4 | 604
Melanoma 4 | 711
Multiple myeloma 4 | 1,332
Neurodegenerative disease 4 | 414
Short stature 4 | 531
active Crohn's disease 4 | 922
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,057
non diabetic and post-ischemic heart failure 4 | 200
substance-related disorder 4 | 162

Tissue

Female tissues 78 | 17,400
Blood and immune system 77 | 16,909
Endocrine System 77 | 18,159
Digestive Tract 76 | 17,369
Nervous System 75 | 16,725
Liver and Pancreas 74 | 16,750
Skin and soft tissues 73 | 17,230
Urinary Tract 73 | 16,678
Male tissues 71 | 17,142
Respiratory system 71 | 16,393
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 44 | 12,091
Enzyme 25 | 4,145
Transporter 5 | 473
oGPCR 4 | 421
Transcription Factor 3 | 1,400
Ion Channel 2 | 344
Kinase 1 | 634
Nuclear Receptor 1 | 48

GWAS Trait

Mean corpuscular hemoglobin co... 85 | 85
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase RNF182 RNF182 Tdark Enzyme 0.06 0.73 104
Probable palmitoyltransferase ZDHHC19 ZDHHC19 Tdark Enzyme 0.73 0.41 48
Hemoglobin subunit zeta HBZ Tbio Non-IDG -2.38422 251.3 201
Interleukin-2 receptor subunit beta IL2RB Tclin Non-IDG -2.17998 125.4 654
Tribbles homolog 1 TRIB1 Tbio Kinase -1.74370 59.4 250
Arginine/serine-rich protein 1 RSRP1 Tdark Non-IDG 0.04 1.12 54
Protein max MAX Tbio Transcription Factor -2.14268 110.6 398
Transferrin receptor protein 2 TFR2 Tbio Enzyme -2.11882 135.2 149
NADPH-dependent diflavin oxidoreductase 1 NDOR1 Tbio Enzyme -0.73362 5.15 159
Transmembrane protein 79 TMEM79 Tbio Non-IDG -2.00064 98.9 62