Development Level

Tbio 172 | 11,651
Tdark 35 | 6,593
Tchem 21 | 1,388
Tclin 10 | 612

Collection

RFA-RM-18-021 2 | 328
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 19 | 979
decreased leukocyte cell numbe... 7 | 73
preweaning lethality, incomple... 7 | 499
abnormal embryo size 6 | 220
increased mean corpuscular hem... 6 | 96
embryonic lethality prior to t... 5 | 278
abnormal behavior 4 | 298
decreased bone mineral content 4 | 151
decreased bone mineral density 4 | 126
decreased circulating choleste... 4 | 93
decreased erythrocyte cell num... 4 | 62
embryonic lethality prior to o... 4 | 239
prenatal lethality prior to he... 4 | 87
abnormal coat-hair pigmentatio... 3 | 64
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
decreased startle reflex 3 | 75
decreased total body fat amoun... 3 | 207
enlarged heart 3 | 210
increased bone mineral density 3 | 72
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased hematocrit 3 | 46
increased mean corpuscular vol... 3 | 92
increased mean platelet volume 3 | 45
mydriasis 3 | 6
prenatal lethality 3 | 28
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal embryo turning 2 | 31
abnormal gait 2 | 69
abnormal motor capabilities-co... 2 | 5
cataract 2 | 92
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating alkaline... 2 | 46
decreased circulating total pr... 2 | 49
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased spleen weight 2 | 10
decreased total retina thickne... 2 | 17
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
impaired pupillary reflex 2 | 26
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased circulating bilirubi... 2 | 16
increased circulating fructosa... 2 | 13
increased circulating iron lev... 2 | 30
increased circulating potassiu... 2 | 29
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
increased prepulse inhibition 2 | 32
long tibia 2 | 25
male infertility 2 | 123
pallor 2 | 34
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
thrombocytopenia 2 | 56
tremors 2 | 39
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal heart looping 1 | 5
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
increased body length 1 | 32
increased body weight 1 | 25
increased circulating aspartat... 1 | 15
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
thrombocytosis 1 | 27
trunk curl 1 | 16

Disease

Carcinoma 152 | 11,493
osteosarcoma 141 | 7,950
ovarian cancer 129 | 8,520
psoriasis 99 | 6,694
medulloblastoma, large-cell 88 | 6,241
glioblastoma 87 | 5,792
lung cancer 79 | 4,740
atypical teratoid / rhabdoid tumor 76 | 5,112
Cancer 66 | 2,499
Breast cancer 63 | 3,578
ependymoma 62 | 4,679
group 3 medulloblastoma 62 | 4,104
adult high grade glioma 52 | 3,801
non-small cell lung cancer 51 | 2,890
malignant mesothelioma 47 | 3,232
invasive ductal carcinoma 46 | 2,951
pancreatic cancer 43 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
lung adenocarcinoma 40 | 2,716
tuberculosis 40 | 2,010
Astrocytoma, Pilocytic 39 | 3,081
pancreatic ductal adenocarcinoma liver metastasis 39 | 1,962
primitive neuroectodermal tumor 39 | 3,035
Kidney cancer 37 | 2,613
subependymal giant cell astrocytoma 34 | 2,287
Peripheral vascular disease 32 | 87
ductal carcinoma in situ 32 | 1,745
interstitial cystitis 32 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
breast carcinoma 31 | 1,638
group 4 medulloblastoma 31 | 1,855
oligodendroglioma 31 | 2,850
diabetes mellitus 30 | 1,728
lung carcinoma 30 | 2,843
Pick disease 29 | 1,894
ulcerative colitis 28 | 1,819
dermatomyositis 27 | 966
astrocytic glioma 26 | 2,597
cystic fibrosis 26 | 1,696
Rheumatoid arthritis 25 | 1,191
juvenile dermatomyositis 25 | 1,187
Anemia 23 | 365
pituitary cancer 23 | 1,972
colon cancer 22 | 1,478
Atopic dermatitis 21 | 952
Autosomal recessive predisposition 20 | 1,442
acute myeloid leukemia 20 | 783
primary Sjogren syndrome 19 | 735
Waldenstrons macroglobulinemia 18 | 765
adrenocortical carcinoma 18 | 1,428
cutaneous lupus erythematosus 18 | 1,057
Schizophrenia 17 | 1,160
astrocytoma 17 | 1,146
pediatric high grade glioma 17 | 1,064
spina bifida 17 | 1,074
Multiple myeloma 16 | 1,332
acute quadriplegic myopathy 16 | 1,158
hepatocellular carcinoma 16 | 547
primary pancreatic ductal adenocarcinoma 16 | 1,109
Hemolytic anemia 15 | 77
non primary Sjogren syndrome sicca 15 | 891
pancreatic carcinoma 15 | 562
esophageal adenocarcinoma 14 | 737
mucosa-associated lymphoid tissue lymphoma 14 | 484
Breast Neoplasms 13 | 445
Kidney disease 13 | 430
Thalassemia 13 | 53
Type 2 diabetes mellitus 13 | 272
nasopharyngeal carcinoma 13 | 1,058
progressive supranuclear palsy 13 | 676
Crohn's disease 12 | 321
Duchenne muscular dystrophy 12 | 601
Mammary Neoplasms 12 | 425
Polycystic ovary syndrome 12 | 360
active ulcerative colitis 12 | 764
atypical teratoid/rhabdoid tumor 12 | 357
Intellectual disability 11 | 1,016
Liver cancer 11 | 604
Obesity 11 | 678
chronic rhinosinusitis 11 | 512
Chronic Lymphocytic Leukemia 10 | 262
Colorectal Neoplasms 10 | 243
Endometriosis 10 | 540
Liver carcinoma 10 | 240
Melanoma 10 | 711
Pancreatic Neoplasms 10 | 85
Parkinson's disease 10 | 392
Prostatic Neoplasms 10 | 495
gastric cancer 10 | 459
gastric carcinoma 10 | 807
Alcoholic Intoxication, Chronic 9 | 289
Alzheimer's disease 9 | 658
Carcinoma, Hepatocellular 9 | 228
Disease Models, Animal 9 | 155
Fatigue 9 | 182
Hepatomegaly 9 | 285
Leukemia, Myelocytic, Acute 9 | 120
Pancreatic Neoplasm 9 | 85
Vascular disease 9 | 319

Tissue

Endocrine System 230 | 18,159
Female tissues 226 | 17,400
Blood and immune system 225 | 16,909
Digestive Tract 224 | 17,369
Liver and Pancreas 222 | 16,750
Nervous System 222 | 16,725
Skin and soft tissues 221 | 17,230
Urinary Tract 221 | 16,678
Male tissues 219 | 17,142
Respiratory system 215 | 16,393
Cardiovascular System 211 | 15,192

Target Family

Non-IDG 122 | 12,091
Enzyme 48 | 4,145
Transcription Factor 34 | 1,400
Kinase 11 | 634
Transporter 10 | 473
Epigenetic 5 | 242
TF/Epigenetic 3 | 38
Nuclear Receptor 2 | 48
oGPCR 2 | 421
Ion Channel 1 | 344

GWAS Trait

Mean corpuscular hemoglobin 238 | 238
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Thymidine phosphorylase TYMP Tclin Enzyme -2.83170 677.8 514
Chromatin assembly factor 1 subunit A CHAF1A Tbio Non-IDG -1.60312 40.7 157
Nuclear receptor coactivator 4 NCOA4 Tbio Non-IDG -2.20245 136.0 283
Protein inturned INTU Tbio Non-IDG -1.76006 53.9 56
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.52487 33.2 60
Neuritin-like protein NRN1L Tdark Non-IDG 0.70 0.20 71
WD repeat domain phosphoinositide-interacting protein 2 WIPI2 Tbio Non-IDG -1.16004 13.0 195
Probable palmitoyltransferase ZDHHC19 ZDHHC19 Tdark Enzyme 0.73 0.41 48
Hemoglobin subunit zeta HBZ Tbio Non-IDG -2.38422 251.3 201