Development Level

Tbio 32 | 11,445
Tdark 8 | 6,588
Tchem 2 | 1,598
Tclin 2 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased vertical activity 3 | 208
decreased grip strength 2 | 116
enlarged heart 2 | 210
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eyelid fusion 1 | 3
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal pericardium morpholog... 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal skin appearance 1 | 3
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased coping response 1 | 8
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
irregularly shaped pupil 1 | 7
mydriasis 1 | 6
polycystic kidney 1 | 15
prenatal lethality 1 | 28
short tibia 1 | 97
shortened RR interval 1 | 17

Disease

Carcinoma 31 | 11,493
ovarian cancer 24 | 8,520
osteosarcoma 16 | 7,950
glioblastoma 14 | 5,792
group 3 medulloblastoma 13 | 4,104
medulloblastoma, large-cell 13 | 6,241
psoriasis 13 | 6,694
lung cancer 12 | 4,740
atypical teratoid / rhabdoid tumor 11 | 5,112
lung adenocarcinoma 11 | 2,716
ependymoma 10 | 4,679
Cancer 9 | 2,499
Kidney cancer 9 | 2,613
oligodendroglioma 9 | 2,850
Breast cancer 8 | 3,578
lung carcinoma 8 | 2,843
primitive neuroectodermal tumor 8 | 3,035
ulcerative colitis 8 | 1,819
Multiple myeloma 7 | 1,332
adult high grade glioma 7 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Astrocytoma, Pilocytic 6 | 3,081
astrocytic glioma 6 | 2,597
interstitial cystitis 6 | 2,312
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Pick disease 5 | 1,894
acute quadriplegic myopathy 5 | 1,158
ductal carcinoma in situ 5 | 1,745
malignant mesothelioma 5 | 3,232
Atopic dermatitis 4 | 952
Autosomal recessive predisposition 4 | 1,442
Koolen de Vries syndrome 4 | 18
Obesity 4 | 678
Parkinson's disease 4 | 392
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
juvenile dermatomyositis 4 | 1,187
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Chronic obstructive pulmonary disease 3 | 184
Craniofacial Abnormalities 3 | 151
Crohn's disease 3 | 321
Down syndrome 3 | 499
Frontal bossing 3 | 157
Hypohidrotic ectodermal dysplasia 3 | 15
Intellectual disability 3 | 1,016
Mental Depression 3 | 333
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
posterior fossa group A ependymoma 3 | 468
progressive supranuclear palsy 3 | 676
Acquired metabolic disease 2 | 336
Alcoholic Intoxication, Chronic 2 | 289
Alopecia 2 | 115
Alopecia universalis 2 | 16
Amyotrophic lateral sclerosis 2 | 451
Big calvaria 2 | 147
Brain disease 2 | 96
Cerebrovascular disease 2 | 238
Clouston syndrome 2 | 9
Depressive disorder 2 | 409
Disease Models, Animal 2 | 155
Endometriosis 2 | 540
Enophthalmos 2 | 75
Essential Hypertension 2 | 94
Heart disease 2 | 306
Hypotrichosis 2 | 47
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Lung Neoplasms 2 | 232
Melanoma 2 | 711
Osteoporosis 2 | 363
Schizophrenia 2 | 1,160
Strabismus 2 | 270
Sunken eyes 2 | 63
Type 2 diabetes mellitus 2 | 272
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
chronic lymphosyte leukemia 2 | 204
cutaneous lupus erythematosus 2 | 1,057
gastric carcinoma 2 | 807
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074

Tissue

Endocrine System 44 | 18,159
Female tissues 42 | 17,400
Male tissues 42 | 17,142
Digestive Tract 41 | 17,369
Liver and Pancreas 41 | 16,750
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Blood and immune system 40 | 16,909
Urinary Tract 40 | 16,678
Nervous System 39 | 16,725
Cardiovascular System 36 | 15,192

Target Family

Non-IDG 25 | 12,091
Transcription Factor 10 | 1,400
Enzyme 5 | 4,145
Epigenetic 2 | 242
GPCR 1 | 408
Transporter 1 | 473

GWAS Trait

Male-pattern baldness 44 | 44
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.71858 56.5 209
Proline-rich protein 23A PRR23A Tdark Non-IDG 0.00000 53
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Muskelin MKLN1 Tbio Non-IDG -1.08451 14.7 102
Homeobox protein aristaless-like 4 ALX4 Tbio Transcription Factor -1.77762 62.7 213
T-box transcription factor TBX15 TBX15 Tbio Transcription Factor -1.29899 21.5 123
Katanin p60 ATPase-containing subunit A-like 1 KATNAL1 Tbio Enzyme -0.86481 6.61 124
Signal peptide peptidase-like 2C SPPL2C Tbio Enzyme -0.29003 1.44 33
FOXL2 neighbor protein FOXL2NB Tdark Non-IDG 0.00000 15
Fibroblast growth factor 5 FGF5 Tbio Non-IDG -2.07061 109.8 192