Development Level

Tbio 62 | 11,445
Tdark 18 | 6,588
Tchem 9 | 1,598
Tclin 5 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased circulating alkaline... 3 | 46
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
increased circulating creatini... 3 | 38
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
decreased body length 2 | 101
decreased caudal vertebrae num... 2 | 53
embryonic lethality prior to o... 2 | 239
increased blood urea nitrogen ... 2 | 48
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal digit morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal motor capabilities-co... 1 | 5
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
brachydactyly 1 | 19
corneal opacity 1 | 32
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased food intake 1 | 13
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
fused cornea and lens 1 | 5
fused phalanges 1 | 1
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
syndactyly 1 | 23
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Carcinoma 63 | 11,493
ovarian cancer 52 | 8,520
glioblastoma 38 | 5,792
osteosarcoma 38 | 7,950
atypical teratoid / rhabdoid tumor 37 | 5,112
medulloblastoma, large-cell 36 | 6,241
Mental Depression 34 | 333
lung cancer 34 | 4,740
psoriasis 34 | 6,694
ependymoma 32 | 4,679
Breast cancer 31 | 3,578
group 3 medulloblastoma 27 | 4,104
malignant mesothelioma 25 | 3,232
oligodendroglioma 25 | 2,850
Astrocytoma, Pilocytic 24 | 3,081
adult high grade glioma 23 | 3,801
primitive neuroectodermal tumor 23 | 3,035
Kidney cancer 22 | 2,613
invasive ductal carcinoma 22 | 2,951
lung carcinoma 21 | 2,843
pituitary cancer 20 | 1,972
ductal carcinoma in situ 19 | 1,745
interstitial cystitis 19 | 2,312
non-small cell lung cancer 18 | 2,890
Pick disease 17 | 1,894
astrocytic glioma 17 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
subependymal giant cell astrocytoma 16 | 2,287
breast carcinoma 15 | 1,638
colon cancer 15 | 1,478
group 4 medulloblastoma 15 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
pancreatic cancer 15 | 2,398
Schizophrenia 14 | 1,160
ulcerative colitis 14 | 1,819
Cancer 13 | 2,499
astrocytoma 12 | 1,146
cystic fibrosis 12 | 1,696
lung adenocarcinoma 12 | 2,716
adrenocortical carcinoma 11 | 1,428
dermatomyositis 10 | 966
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
pediatric high grade glioma 10 | 1,064
tuberculosis 10 | 2,010
Bipolar Disorder 9 | 666
Rheumatoid arthritis 9 | 1,191
diabetes mellitus 9 | 1,728
Atopic dermatitis 8 | 952
Liver cancer 8 | 604
active Crohn's disease 8 | 922
acute quadriplegic myopathy 8 | 1,158
Depressive disorder 7 | 409
Intellectual disability 7 | 1,016
Liver Cirrhosis, Experimental 7 | 769
Obesity 7 | 678
gastric carcinoma 7 | 807
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Autosomal recessive predisposition 6 | 1,442
Duchenne muscular dystrophy 6 | 601
Epilepsy 6 | 792
aldosterone-producing adenoma 6 | 665
cutaneous lupus erythematosus 6 | 1,057
medulloblastoma 6 | 720
Alzheimer's disease 5 | 658
Autistic Disorder 5 | 364
Cognitive delay 5 | 608
Dull intelligence 5 | 645
Endometriosis 5 | 540
Global developmental delay 5 | 608
Kidney disease 5 | 430
Low intelligence 5 | 645
Melanoma 5 | 711
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Multiple myeloma 5 | 1,332
Poor school performance 5 | 645
active ulcerative colitis 5 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
nasopharyngeal carcinoma 5 | 1,058
posterior fossa group A ependymoma 5 | 468
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alcoholic Intoxication, Chronic 4 | 289
Attention deficit hyperactivity disorder 4 | 278
Cardiovascular system disease 4 | 246
Cataract 4 | 297
Glaucoma 4 | 239
Lens Opacities 4 | 231
Optic Atrophy 4 | 242
Seizures 4 | 596
Short stature 4 | 531
Skin cancer 4 | 469
Type 2 diabetes mellitus 4 | 272
atypical teratoid/rhabdoid tumor 4 | 357
cystic fibrosis and chronic rhinosinusitis 4 | 214
juvenile dermatomyositis 4 | 1,187
nephrosclerosis 4 | 333
pancreatic carcinoma 4 | 562
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074

Tissue

Endocrine System 89 | 18,159
Digestive Tract 86 | 17,369
Female tissues 85 | 17,400
Male tissues 85 | 17,142
Liver and Pancreas 83 | 16,750
Nervous System 83 | 16,725
Skin and soft tissues 83 | 17,230
Urinary Tract 83 | 16,678
Blood and immune system 80 | 16,909
Cardiovascular System 80 | 15,192
Respiratory system 79 | 16,393

Target Family

Non-IDG 64 | 12,091
Enzyme 14 | 4,145
Ion Channel 5 | 344
Kinase 4 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 408
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GWAS Trait

Major depressive disorder 94 | 94
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Doublesex- and mab-3-related transcription factor 1 DMRT1 Tbio Transcription Factor -2.31269 210.5 197
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Epithelial membrane protein 1 EMP1 Tbio Non-IDG -2.60119 387.7 88
CASP8-associated protein 2 CASP8AP2 Tbio Non-IDG 0.00000 0
Zinc finger protein 608 ZNF608 Tdark Non-IDG -0.47998 2.60 62
Putative uncharacterized protein encoded by LINC01559 LINC01559 Tdark Non-IDG 0.00000 0
Transmembrane and coiled-coil domain-containing protein 5B TMCO5B Tdark Non-IDG 0.00000 0
Oral cancer-overexpressed protein 1 ORAOV1 Tbio Non-IDG -1.06859 14.3 41
Protein C8orf37 C8orf37 Tbio Non-IDG -2.10097 123.4 32
Unconventional myosin-X MYO10 Tbio Non-IDG -1.49855 36.4 47