Development Level

Tbio 10 | 11,445
Tchem 4 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased erythrocyte cell num... 3 | 62
abnormal locomotor activation 2 | 16
abnormal startle reflex 2 | 15
decreased body weight 2 | 161
decreased circulating iron lev... 2 | 32
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
increased blood urea nitrogen ... 2 | 48
increased circulating amylase ... 2 | 25
increased lean body mass 2 | 172
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
preweaning lethality, incomple... 2 | 499
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal spleen morphology 1 | 55
decreased lean body mass 1 | 135
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 16 | 11,493
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
lung cancer 9 | 4,740
psoriasis 8 | 6,694
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung carcinoma 7 | 2,843
medulloblastoma, large-cell 7 | 6,241
Astrocytoma, Pilocytic 6 | 3,081
Kidney cancer 6 | 2,613
glioblastoma 6 | 5,792
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
Breast cancer 5 | 3,578
Pick disease 5 | 1,894
invasive ductal carcinoma 5 | 2,951
spina bifida 5 | 1,074
Cancer 4 | 2,499
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
malignant mesothelioma 4 | 3,232
Brachydactyly 3 | 156
Gout 3 | 106
Melanoma 3 | 711
Radioulnar synostosis 3 | 35
Skin cancer 3 | 469
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
ependymoma 3 | 4,679
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
Acne 2 | 52
Autosomal recessive predisposition 2 | 1,442
Barrett's esophagus 2 | 182
Bilateral fifth finger clinodactyly 2 | 110
Breast Neoplasms 2 | 445
Cell Transformation, Neoplastic 2 | 97
Curvature of little finger 2 | 110
Diastrophic dysplasia 2 | 21
Endometriosis 2 | 540
Gamma chain deficiency 2 | 7
Hirsutism 2 | 47
Hypertensive disease 2 | 292
Increase in blood pressure 2 | 119
Intellectual disability 2 | 1,016
Leukemia 2 | 104
Liver cancer 2 | 604
MYELODYSPLASTIC SYNDROME 2 | 53
Mammary Neoplasms 2 | 425
Multiple myeloma 2 | 1,332
Neoplastic Cell Transformation 2 | 89
Osteoporosis 2 | 363
Ovarian Neoplasms 2 | 102
Radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome 2 | 3
Short stature 2 | 531
Stomach Neoplasms 2 | 300
Syndactyly 2 | 88
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
chronic kidney disease 2 | 90
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
facioscapulohumeral dystrophy 2 | 288
hereditary spastic paraplegia 2 | 318
inflammatory breast cancer 2 | 286
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
oligodendroglioma 2 | 2,850
ovarian neoplasm 2 | 99
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Abnormality of the nasopharynx 1 | 9
Arachnoid Cysts 1 | 5
Blepharospasm 1 | 13
Burns, Chemical 1 | 6
Craniofacial dysostosis type 1 1 | 2
Dextraposition of aorta 1 | 3
Distal 10q deletion syndrome 1 | 5
Hypomagnesemia 1, Intestinal 1 | 1
Keratoconjunctivitis 1 | 14
Multiple suture craniosynostosis 1 | 2
Overriding aorta 1 | 3
Peritoneal Neoplasms 1 | 10
Synostosis of carpal bones 1 | 9

Tissue

Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Nervous System 15 | 16,725
Urinary Tract 15 | 16,678
Cardiovascular System 13 | 15,192

Target Family

Enzyme 5 | 4,145
Non-IDG 5 | 12,091
Kinase 3 | 634
Epigenetic 1 | 242
GPCR 1 | 408
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400
oGPCR 1 | 421

GWAS Trait

Magnesium levels 18 | 18
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-1 MUC1 Tbio Non-IDG -3.54835 3730.1 2598
Fibroblast growth factor receptor 2 FGFR2 Tclin Kinase -3.08664 1210.6 948
Vasoactive intestinal polypeptide receptor 1 VIPR1 Tchem GPCR -2.64209 410.6 324
Transient receptor potential cation channel subfamily M member 6 TRPM6 Tchem Kinase -2.17477 147.0 101
MDS1 and EVI1 complex locus protein MDS1 MECOM Tbio Non-IDG -1.84060 124.5 0
MDS1 and EVI1 complex locus protein EVI1 MECOM Tbio TF/Epigenetic -1.84060 124.5 317
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 PAPSS2 Tbio Enzyme -1.63983 42.6 186
Protein Shroom3 SHROOM3 Tbio Non-IDG -1.57599 36.8 31
Homeobox protein Hox-D9 HOXD9 Tbio Transcription Factor -1.52954 36.2 137
Tripartite motif-containing protein 46 TRIM46 Tbio Non-IDG -1.51367 30.5 78