Development Level

Tbio 75 | 11,445
Tdark 23 | 6,588
Tchem 16 | 1,598
Tclin 8 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal behavior 6 | 298
preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 6 | 499
decreased bone mineral content 4 | 151
decreased heart weight 4 | 27
increased circulating alkaline... 4 | 122
abnormal embryo size 3 | 220
decreased bone mineral density 3 | 126
decreased circulating glucose ... 3 | 126
decreased lean body mass 3 | 135
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased circulating HDL chol... 3 | 80
increased circulating creatini... 3 | 38
increased grip strength 3 | 41
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal eye anterior chamber ... 2 | 9
abnormal eye morphology 2 | 68
abnormal kidney morphology 2 | 65
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating chloride... 2 | 30
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased vertical activity 2 | 208
enlarged heart 2 | 210
hyperactivity 2 | 148
increased body length 2 | 32
increased circulating calcium ... 2 | 34
increased circulating choleste... 2 | 66
increased circulating phosphat... 2 | 26
increased circulating total pr... 2 | 28
increased fasted circulating g... 2 | 76
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
short tibia 2 | 97
tremors 2 | 39
trunk curl 2 | 16
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41
microphthalmia 1 | 26
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74

Disease

Carcinoma 82 | 11,493
osteosarcoma 75 | 7,950
ovarian cancer 66 | 8,520
glioblastoma 51 | 5,792
psoriasis 49 | 6,694
medulloblastoma, large-cell 45 | 6,241
lung cancer 44 | 4,740
adult high grade glioma 40 | 3,801
Cancer 36 | 2,499
atypical teratoid / rhabdoid tumor 35 | 5,112
ependymoma 34 | 4,679
Astrocytoma, Pilocytic 33 | 3,081
Breast cancer 33 | 3,578
invasive ductal carcinoma 33 | 2,951
lung carcinoma 33 | 2,843
tuberculosis 32 | 2,010
non-small cell lung cancer 31 | 2,890
interstitial cystitis 29 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
lung adenocarcinoma 28 | 2,716
Rheumatoid arthritis 27 | 1,191
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
pancreatic cancer 26 | 2,398
primitive neuroectodermal tumor 26 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
malignant mesothelioma 25 | 3,232
ulcerative colitis 25 | 1,819
Kidney cancer 23 | 2,613
subependymal giant cell astrocytoma 23 | 2,287
group 3 medulloblastoma 21 | 4,104
oligodendroglioma 21 | 2,850
pituitary cancer 21 | 1,972
ductal carcinoma in situ 19 | 1,745
group 4 medulloblastoma 19 | 1,855
juvenile dermatomyositis 19 | 1,187
cystic fibrosis 18 | 1,696
Crohn's disease 17 | 321
astrocytic glioma 17 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Multiple Sclerosis 15 | 540
primary Sjogren syndrome 15 | 735
active Crohn's disease 14 | 922
acute quadriplegic myopathy 14 | 1,158
breast carcinoma 14 | 1,638
Asthma 13 | 385
astrocytoma 13 | 1,146
primary pancreatic ductal adenocarcinoma 13 | 1,109
Intellectual disability 12 | 1,016
Multiple myeloma 12 | 1,332
Pick disease 12 | 1,894
acute myeloid leukemia 12 | 783
cutaneous lupus erythematosus 12 | 1,057
non primary Sjogren syndrome sicca 12 | 891
spina bifida 12 | 1,074
active ulcerative colitis 11 | 764
colon cancer 11 | 1,478
esophageal adenocarcinoma 11 | 737
Anemia 10 | 365
Atopic dermatitis 10 | 952
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
gastric carcinoma 10 | 807
hepatocellular carcinoma 10 | 547
mucosa-associated lymphoid tissue lymphoma 10 | 484
Hypersensitivity reaction type II disease 9 | 253
gastric cancer 9 | 459
Acquired metabolic disease 8 | 336
Breast Neoplasms 8 | 445
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mammary Neoplasms 8 | 425
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Obesity 8 | 678
Pneumonia 8 | 174
Poor school performance 8 | 645
Prostatic Neoplasms 8 | 495
Schizophrenia 8 | 1,160
Splenomegaly 8 | 190
adrenocortical carcinoma 8 | 1,428
dermatomyositis 8 | 966
diabetes mellitus 8 | 1,728
medulloblastoma 8 | 720
pediatric high grade glioma 8 | 1,064
Autistic Disorder 7 | 364
Autosomal recessive predisposition 7 | 1,442
Common variable immunodeficiency 7 | 101
Duchenne muscular dystrophy 7 | 601
Human immunodeficiency virus infectious disease 7 | 138
Inflammatory bowel disease 7 | 151
Systemic lupus erythematosus 7 | 194
aldosterone-producing adenoma 7 | 665
chronic lymphosyte leukemia 7 | 204
periodontitis 7 | 293
posterior fossa group A ependymoma 7 | 468
sarcoidosis 7 | 370
Arthritis, Rheumatoid 6 | 174
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Muscle hypotonia 6 | 571

Tissue

Endocrine System 118 | 18,159
Blood and immune system 116 | 16,909
Respiratory system 116 | 16,393
Digestive Tract 115 | 17,369
Female tissues 115 | 17,400
Nervous System 115 | 16,725
Liver and Pancreas 113 | 16,750
Male tissues 113 | 17,142
Skin and soft tissues 113 | 17,230
Urinary Tract 113 | 16,678
Cardiovascular System 107 | 15,192

Target Family

Non-IDG 65 | 12,091
Transcription Factor 20 | 1,400
Enzyme 16 | 4,145
Kinase 7 | 634
Epigenetic 5 | 242
GPCR 5 | 408
oGPCR 2 | 421
Nuclear Receptor 1 | 48
Transporter 1 | 473

GWAS Trait

Lymphocyte percentage of white... 122 | 122
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.48051 278.1 378
Histone-lysine N-methyltransferase SETD2 SETD2 Tchem Epigenetic -2.83266 645.3 214
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94
T-lymphocyte surface antigen Ly-9 LY9 Tbio Non-IDG -1.58527 43.8 383
Selenide, water dikinase 2 SEPHS2 Tdark Enzyme -1.42671 25.3 0
Interferon-induced transmembrane protein 2 IFITM2 Tbio Non-IDG -2.24139 171.1 155
Protein NLRC5 NLRC5 Tbio Non-IDG -1.74276 63.6 44
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
GTP:AMP phosphotransferase AK3, mitochondrial AK3 Tbio Kinase -1.37969 23.5 249