Development Level

Tbio 99 | 11,445
Tchem 29 | 1,598
Tdark 21 | 6,588
Tclin 9 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 12 | 979
abnormal bone structure 7 | 187
preweaning lethality, incomple... 7 | 499
decreased bone mineral content 6 | 151
decreased bone mineral density 6 | 126
abnormal behavior 4 | 298
abnormal embryo size 4 | 220
decreased total body fat amoun... 4 | 207
increased circulating HDL chol... 4 | 80
increased circulating alkaline... 4 | 122
increased total body fat amoun... 4 | 134
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased body length 3 | 101
decreased lean body mass 3 | 135
decreased startle reflex 3 | 75
edema 3 | 59
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
hypoactivity 3 | 132
increased circulating choleste... 3 | 66
increased grip strength 3 | 41
increased startle reflex 3 | 112
short tibia 3 | 97
abnormal eye anterior chamber ... 2 | 9
abnormal heart morphology 2 | 162
abnormal pelvic girdle bone mo... 2 | 12
abnormal retina morphology 2 | 71
abnormal vertebrae morphology 2 | 18
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating amylase ... 2 | 28
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased fasted circulating g... 2 | 65
decreased large unstained cell... 2 | 11
decreased mean corpuscular vol... 2 | 79
embryonic lethality prior to o... 2 | 239
increased circulating calcium ... 2 | 34
increased fasted circulating g... 2 | 76
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased neutrophil cell numb... 2 | 46
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
thrombocytopenia 2 | 56
abnormal allantois morphology 1 | 8
abnormal body wall morphology 1 | 9
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal response to new envir... 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal tail bud morphology 1 | 8
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
cleft palate 1 | 8
corneal opacity 1 | 32
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased heart rate 1 | 23
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
prenatal lethality 1 | 28
unresponsive to tactile stimul... 1 | 8
vertebral fusion 1 | 23

Disease

Carcinoma 109 | 11,493
osteosarcoma 97 | 7,950
ovarian cancer 90 | 8,520
psoriasis 69 | 6,694
glioblastoma 66 | 5,792
lung cancer 65 | 4,740
medulloblastoma, large-cell 57 | 6,241
ependymoma 51 | 4,679
Cancer 49 | 2,499
atypical teratoid / rhabdoid tumor 49 | 5,112
Breast cancer 46 | 3,578
lung carcinoma 44 | 2,843
non-small cell lung cancer 44 | 2,890
adult high grade glioma 43 | 3,801
Astrocytoma, Pilocytic 42 | 3,081
invasive ductal carcinoma 42 | 2,951
interstitial cystitis 40 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
group 3 medulloblastoma 36 | 4,104
subependymal giant cell astrocytoma 34 | 2,287
Kidney cancer 33 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
malignant mesothelioma 33 | 3,232
oligodendroglioma 32 | 2,850
tuberculosis 32 | 2,010
ulcerative colitis 31 | 1,819
primitive neuroectodermal tumor 30 | 3,035
lung adenocarcinoma 29 | 2,716
pancreatic cancer 29 | 2,398
Rheumatoid arthritis 27 | 1,191
astrocytic glioma 27 | 2,597
cystic fibrosis 25 | 1,696
pituitary cancer 25 | 1,972
primary Sjogren syndrome 25 | 735
group 4 medulloblastoma 23 | 1,855
cutaneous lupus erythematosus 22 | 1,057
ductal carcinoma in situ 22 | 1,745
Multiple Sclerosis 21 | 540
Schizophrenia 21 | 1,160
Crohn's disease 20 | 321
juvenile dermatomyositis 20 | 1,187
diabetes mellitus 19 | 1,728
Pick disease 18 | 1,894
astrocytoma 17 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
primary pancreatic ductal adenocarcinoma 17 | 1,109
Liver Cirrhosis, Experimental 16 | 769
breast carcinoma 16 | 1,638
Asthma 14 | 385
Intellectual disability 14 | 1,016
Melanoma 14 | 711
Multiple myeloma 14 | 1,332
Waldenstrons macroglobulinemia 14 | 765
active Crohn's disease 14 | 922
acute quadriplegic myopathy 14 | 1,158
Autosomal recessive predisposition 13 | 1,442
Acquired metabolic disease 12 | 336
Bipolar Disorder 12 | 666
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Hypersensitivity reaction type II disease 12 | 253
Mental and motor retardation 12 | 608
Type 1 diabetes mellitus 12 | 109
adrenocortical carcinoma 12 | 1,428
colon cancer 12 | 1,478
nasopharyngeal carcinoma 12 | 1,058
pediatric high grade glioma 12 | 1,064
Systemic lupus erythematosus 11 | 194
Type 2 diabetes mellitus 11 | 272
Vascular disease 11 | 319
gastric carcinoma 11 | 807
spina bifida 11 | 1,074
Short stature 10 | 531
Splenomegaly 10 | 190
active ulcerative colitis 10 | 764
dermatomyositis 10 | 966
Atherosclerosis 9 | 291
Chronic Lymphocytic Leukemia 9 | 262
Dull intelligence 9 | 645
Epilepsy 9 | 792
Human immunodeficiency virus infectious disease 9 | 138
Liver cancer 9 | 604
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Obesity 9 | 678
Poor school performance 9 | 645
Prostatic Neoplasms 9 | 495
acute myeloid leukemia 9 | 783
non primary Sjogren syndrome sicca 9 | 891
Arthritis 8 | 290
Atopic dermatitis 8 | 952
Diabetes Mellitus, Non-Insulin-Dependent 8 | 145
Diabetes Mellitus, Type 2 8 | 142
Duchenne muscular dystrophy 8 | 601
Immune system cancer 8 | 140
Muscle hypotonia 8 | 571
aldosterone-producing adenoma 8 | 665
gastric cancer 8 | 459

Tissue

Blood and immune system 154 | 16,909
Endocrine System 154 | 18,159
Digestive Tract 152 | 17,369
Skin and soft tissues 152 | 17,230
Female tissues 151 | 17,400
Liver and Pancreas 150 | 16,750
Urinary Tract 150 | 16,678
Respiratory system 149 | 16,393
Male tissues 148 | 17,142
Nervous System 148 | 16,725
Cardiovascular System 142 | 15,192

Target Family

Non-IDG 73 | 12,091
Enzyme 34 | 4,145
Transcription Factor 25 | 1,400
Kinase 8 | 634
Epigenetic 7 | 242
Transporter 6 | 473
GPCR 3 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GWAS Trait

Lymphocyte counts 158 | 158
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
TRAF2 and NCK-interacting protein kinase TNIK Tchem Kinase -1.33394 28.5 441
Protein NLRC5 NLRC5 Tbio Non-IDG -1.74276 63.6 44
HORMA domain-containing protein 1 HORMAD1 Tbio Non-IDG -1.44656 27.9 135
Krueppel-like factor 2 KLF2 Tbio Transcription Factor -2.30630 216.2 308
Eomesodermin homolog EOMES Tbio Transcription Factor -2.37902 230.4 333
Krueppel-like factor 12 KLF12 Tbio Transcription Factor -1.36344 19.7 185
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94
Selenide, water dikinase 2 SEPHS2 Tdark Enzyme -1.42671 25.3 0
T-lymphocyte surface antigen Ly-9 LY9 Tbio Non-IDG -1.58527 43.8 383