Development Level

Tbio 83 | 11,445
Tchem 17 | 1,598
Tdark 17 | 6,588
Tclin 5 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
preweaning lethality, complete... 5 | 979
abnormal behavior 4 | 298
decreased total body fat amoun... 4 | 207
decreased circulating insulin ... 3 | 76
decreased vertical activity 3 | 208
enlarged heart 3 | 210
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal epididymis morphology 2 | 42
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal neural tube closure 2 | 46
cataract 2 | 92
decreased fasted circulating g... 2 | 65
decreased lymphocyte cell numb... 2 | 83
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased startle reflex 2 | 112
small superior vagus ganglion 2 | 74
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal midbrain development 1 | 20
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating lactate ... 1 | 3
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
enlarged spleen 1 | 41
enlarged testis 1 | 6
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased circulating aspartat... 1 | 15
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
pale yolk sac 1 | 25
pallor 1 | 34
prolonged RR interval 1 | 8
small adrenal glands 1 | 16
small testis 1 | 58
thick ventricular wall 1 | 7

Disease

Carcinoma 87 | 11,493
ovarian cancer 67 | 8,520
osteosarcoma 54 | 7,950
psoriasis 52 | 6,694
medulloblastoma, large-cell 49 | 6,241
glioblastoma 48 | 5,792
lung cancer 44 | 4,740
atypical teratoid / rhabdoid tumor 41 | 5,112
Breast cancer 36 | 3,578
adult high grade glioma 35 | 3,801
ependymoma 33 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
lung adenocarcinoma 30 | 2,716
Kidney cancer 29 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
lung carcinoma 26 | 2,843
group 3 medulloblastoma 25 | 4,104
malignant mesothelioma 25 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
pancreatic cancer 24 | 2,398
primitive neuroectodermal tumor 24 | 3,035
Cancer 23 | 2,499
Astrocytoma, Pilocytic 22 | 3,081
invasive ductal carcinoma 22 | 2,951
interstitial cystitis 21 | 2,312
oligodendroglioma 19 | 2,850
tuberculosis 19 | 2,010
Rheumatoid arthritis 18 | 1,191
Schizophrenia 18 | 1,160
Lung Neoplasms 17 | 232
astrocytic glioma 17 | 2,597
non-small cell lung cancer 17 | 2,890
subependymal giant cell astrocytoma 17 | 2,287
ulcerative colitis 17 | 1,819
Pick disease 15 | 1,894
pituitary cancer 15 | 1,972
breast carcinoma 14 | 1,638
cystic fibrosis 14 | 1,696
juvenile dermatomyositis 14 | 1,187
colon cancer 13 | 1,478
ductal carcinoma in situ 13 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Melanoma 12 | 711
astrocytoma 12 | 1,146
spina bifida 12 | 1,074
Liver Cirrhosis, Experimental 11 | 769
pediatric high grade glioma 11 | 1,064
Multiple Sclerosis 10 | 540
Prostatic Neoplasms 10 | 495
acute quadriplegic myopathy 10 | 1,158
cutaneous lupus erythematosus 10 | 1,057
group 4 medulloblastoma 10 | 1,855
primary pancreatic ductal adenocarcinoma 10 | 1,109
substance-related disorder 10 | 162
Adenocarcinoma 9 | 122
esophageal adenocarcinoma 9 | 737
non primary Sjogren syndrome sicca 9 | 891
non-small cell lung carcinoma 9 | 317
Atopic dermatitis 8 | 952
Endometriosis 8 | 540
adrenocortical carcinoma 8 | 1,428
medulloblastoma 8 | 720
Alzheimer's disease 7 | 658
Breast Neoplasms 7 | 445
Intellectual disability 7 | 1,016
Liver cancer 7 | 604
dermatomyositis 7 | 966
nasopharyngeal carcinoma 7 | 1,058
primary Sjogren syndrome 7 | 735
progressive supranuclear palsy 7 | 676
Acquired metabolic disease 6 | 336
Autosomal recessive predisposition 6 | 1,442
Chronic obstructive pulmonary disease 6 | 184
Colorectal Neoplasms 6 | 243
Coronary artery disease 6 | 268
Down syndrome 6 | 499
Mammary Neoplasms 6 | 425
Osteoporosis 6 | 363
Prostate cancer 6 | 175
Skin cancer 6 | 469
diabetes mellitus 6 | 1,728
fibroadenoma 6 | 559
gastric carcinoma 6 | 807
nephrosclerosis 6 | 333
Cognitive delay 5 | 608
Crohn's disease 5 | 321
Dull intelligence 5 | 645
Glaucoma 5 | 239
Global developmental delay 5 | 608
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Multiple myeloma 5 | 1,332
Polycystic ovary syndrome 5 | 360
Poor school performance 5 | 645
Seizures 5 | 596
Short stature 5 | 531
aldosterone-producing adenoma 5 | 665
hereditary spastic paraplegia 5 | 318

Tissue

Endocrine System 117 | 18,159
Digestive Tract 116 | 17,369
Female tissues 115 | 17,400
Skin and soft tissues 114 | 17,230
Male tissues 113 | 17,142
Blood and immune system 111 | 16,909
Liver and Pancreas 110 | 16,750
Respiratory system 109 | 16,393
Urinary Tract 109 | 16,678
Nervous System 108 | 16,725
Cardiovascular System 97 | 15,192

Target Family

Non-IDG 70 | 12,091
Enzyme 18 | 4,145
Transcription Factor 10 | 1,400
Kinase 7 | 634
Transporter 6 | 473
Ion Channel 4 | 344
Epigenetic 3 | 242
GPCR 2 | 408
Nuclear Receptor 1 | 48
oGPCR 1 | 421

GWAS Trait

Lung cancer 122 | 122
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Butyrophilin-like protein 2 BTNL2 Tbio Non-IDG -2.57312 369.3 73
Solute carrier family 12 member 7 SLC12A7 Tbio Transporter -1.46102 28.2 156
Adenylate kinase isoenzyme 5 AK5 Tbio Kinase -1.83209 76.0 225
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
Gastrokine-2 GKN2 Tbio Non-IDG -2.35485 155.7 66
Numb-like protein NUMBL Tbio Non-IDG -2.50313 317.9 171
Myotubularin-related protein 3 MTMR3 Tbio Enzyme -1.05980 10.7 33
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.73498 53.1 39
Psoriasis susceptibility 1 candidate gene 1 protein PSORS1C1 Tbio Non-IDG -0.99481 11.0 63
Discoidin, CUB and LCCL domain-containing protein 1 DCBLD1 Tdark Non-IDG 0.03 0.56 18