Development Level

Tbio 25 | 11,445
Tdark 8 | 6,588
Tchem 4 | 1,598
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

decreased total body fat amoun... 5 | 207
decreased lean body mass 4 | 135
preweaning lethality, complete... 4 | 979
abnormal bone structure 3 | 187
decreased circulating alkaline... 3 | 46
decreased grip strength 3 | 116
increased circulating alkaline... 3 | 122
increased circulating amylase ... 3 | 25
increased circulating chloride... 3 | 41
increased lean body mass 3 | 172
increased red blood cell distr... 3 | 34
short tibia 3 | 97
abnormal locomotor behavior 2 | 24
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
enlarged stomach 2 | 2
impaired glucose tolerance 2 | 75
increased circulating iron lev... 2 | 30
increased hematocrit 2 | 46
increased total body fat amoun... 2 | 134
small thymus 2 | 16
tremors 2 | 39
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal limb morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal response to tactile s... 1 | 17
abnormal skin appearance 1 | 3
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased caudal vertebrae num... 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating phosphat... 1 | 26
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 28 | 11,493
medulloblastoma, large-cell 21 | 6,241
psoriasis 21 | 6,694
osteosarcoma 18 | 7,950
ependymoma 17 | 4,679
glioblastoma 17 | 5,792
ovarian cancer 17 | 8,520
atypical teratoid / rhabdoid tumor 14 | 5,112
primitive neuroectodermal tumor 14 | 3,035
Astrocytoma, Pilocytic 13 | 3,081
Kidney cancer 13 | 2,613
lung cancer 13 | 4,740
malignant mesothelioma 13 | 3,232
adult high grade glioma 11 | 3,801
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
Breast cancer 10 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung carcinoma 9 | 2,843
non-small cell lung cancer 9 | 2,890
oligodendroglioma 9 | 2,850
pituitary cancer 9 | 1,972
subependymal giant cell astrocytoma 9 | 2,287
Pick disease 8 | 1,894
interstitial cystitis 8 | 2,312
lung adenocarcinoma 8 | 2,716
Alzheimer's disease 7 | 658
Autistic Disorder 7 | 364
Bipolar Disorder 7 | 666
Cancer 7 | 2,499
Schizophrenia 7 | 1,160
astrocytic glioma 7 | 2,597
cystic fibrosis 7 | 1,696
tuberculosis 7 | 2,010
Intellectual disability 6 | 1,016
Liver cancer 6 | 604
Rheumatoid arthritis 6 | 1,191
breast carcinoma 6 | 1,638
group 4 medulloblastoma 6 | 1,855
invasive ductal carcinoma 6 | 2,951
pancreatic cancer 6 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Alcoholic Intoxication, Chronic 5 | 289
Endometrial cancer 5 | 311
Epilepsy 5 | 792
Obesity 5 | 678
Vascular disease 5 | 319
astrocytoma 5 | 1,146
ductal carcinoma in situ 5 | 1,745
pediatric high grade glioma 5 | 1,064
ulcerative colitis 5 | 1,819
Asperger syndrome 4 | 37
Autism spectrum disorder 4 | 101
Cardiovascular system disease 4 | 246
Endometriosis 4 | 540
Lipid metabolism disorder 4 | 114
Prostatic Neoplasms 4 | 495
acute myeloid leukemia 4 | 783
colon cancer 4 | 1,478
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
Atopic dermatitis 3 | 952
Autism Spectrum Disorders 3 | 75
Autosomal recessive predisposition 3 | 1,442
Childhood disintegrative disease 3 | 4
Cognitive disorder 3 | 50
Depressive disorder 3 | 409
Dull intelligence 3 | 645
Inflammation 3 | 120
Low intelligence 3 | 645
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Mucositis 3 | 29
Multiple myeloma 3 | 1,332
Nicotine dependence 3 | 54
Poor school performance 3 | 645
Pulmonary Fibrosis 3 | 106
Seizures 3 | 596
Unipolar Depression 3 | 250
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 459
interstitial lung disease 3 | 298
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
Abortion, Spontaneous 2 | 109
Chronic obstructive pulmonary disease 2 | 184
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Polycystic ovary syndrome 2 | 360
Spontaneous abortion 2 | 113
Type 2 diabetes mellitus 2 | 272
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 559

Tissue

Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Male tissues 37 | 17,142
Skin and soft tissues 37 | 17,230
Liver and Pancreas 36 | 16,750
Nervous System 36 | 16,725
Urinary Tract 35 | 16,678
Blood and immune system 34 | 16,909
Respiratory system 33 | 16,393
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 24 | 12,091
Enzyme 5 | 4,145
Ion Channel 3 | 344
GPCR 2 | 408
Kinase 2 | 634
Transcription Factor 2 | 1,400
Transporter 2 | 473

GWAS Trait

Longevity 40 | 40
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Serine/threonine-protein kinase 24 STK24 Tchem Kinase -2.24110 132.9 243
Lateral signaling target protein 2 homolog ZFYVE28 Tbio Non-IDG 0.04 0.75 77
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
Transient receptor potential cation channel subfamily M member 3 TRPM3 Tchem Ion Channel -2.19236 141.8 121
Uncharacterized protein C7orf50 C7orf50 Tdark Non-IDG 0.48 0.33 87
Gamma-aminobutyric acid receptor subunit beta-3 GABRB3 Tclin Ion Channel -2.13205 136.0 202
BEN domain-containing protein 4 BEND4 Tdark Non-IDG 0.24 0.58 101
Cysteine--tRNA ligase, cytoplasmic CARS Tbio Enzyme -3.00492 954.7 154