Development Level

Tbio 8 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
decreased vertical activity 2 | 208
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
abnormal cranium morphology 1 | 36
abnormal heart morphology 1 | 162
abnormal incisor morphology 1 | 4
abnormal joint morphology 1 | 23
abnormal mandible morphology 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating potassiu... 1 | 20
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased anti-nuclear antigen... 1 | 19
increased heart weight 1 | 62
increased total body fat amoun... 1 | 134

Disease

Carcinoma 7 | 11,493
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
medulloblastoma, large-cell 5 | 6,241
Kidney cancer 4 | 2,613
adult high grade glioma 4 | 3,801
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
primitive neuroectodermal tumor 4 | 3,035
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Multiple myeloma 3 | 1,332
astrocytic glioma 3 | 2,597
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
Acquired metabolic disease 2 | 336
Alzheimer's disease 2 | 658
Autosomal recessive hypohidrotic ectodermal dysplasia syndrome 2 | 3
Autosomal recessive predisposition 2 | 1,442
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Ectodermal Dysplasia 10A, Hypohidrotic/Hair/Nail Type, Autosomal Dominant 2 | 3
Hypohidrotic ectodermal dysplasia 2 | 15
Intellectual disability 2 | 1,016
Liver cancer 2 | 604
Melanoma 2 | 711
Skin cancer 2 | 469
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
colon cancer 2 | 1,478
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
non-small cell lung carcinoma 2 | 317
pituitary cancer 2 | 1,972
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Abnormality of female internal genitalia 1 | 13
Abnormality of the fingernails 1 | 51
Acute necrotizing encephalitis 1 | 2
Anhidrosis 1 | 23
Anophthalmos 1 | 13
Aplasia/Hypoplasia of the earlobes 1 | 10
Autosomal dominant hypohidrotic ectodermal dysplasia syndrome (disorder) 1 | 3
Autosomal recessive hypohidrotic ectodermal dysplasia 1 | 3
Blastic phase chronic myeloid leukemia 1 | 58
CHARGE syndrome 1 | 26
Choanal Atresia 1 | 42
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Ciliopathy 1 | 71
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Deglutition Disorders 1 | 132
Delayed Puberty 1 | 97
Dental abnormalities 1 | 60
Developmental absence of tooth 1 | 7
Ectodermal Dysplasia 1 | 14
Ectodermal Dysplasia 3, Anhidrotic 1 | 2
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive 1 | 3
Entropion 1 | 22
Esophageal atresia 1 | 43
Everted lower lip vermilion 1 | 54
Facial asymmetry 1 | 32
Fine hair 1 | 42
Fundus coloboma 1 | 18
Gynecomastia 1 | 64
Hypocalcemia 1 | 32
Hypodontia 1 | 81
Idiopathic hypogonadotropic hypogonadism 1 | 21
Inflammatory myofibroblastic tumor 1 | 8
Iron metabolism disease 1 | 20
Microdontia (disorder) 1 | 59
Narrow face 1 | 54
Obsessive compulsive behavior 1 | 25
Overfolded helix 1 | 24
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Postnatal growth retardation 1 | 57
Primary physiologic amenorrhea 1 | 55
Protruding lower lip 1 | 54
Pulmonary Stenosis 1 | 45
Reye syndrome 1 | 11
Slow-growing hair 1 | 19
Small testicle 1 | 75
Sparse axillary hair 1 | 28
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Sparse pubic hair 1 | 31
Thick vermilion border 1 | 25
Thin face 1 | 54
Tooth Abnormalities 1 | 69
Tooth hypoplasia 1 | 7
VACTERL association 1 | 26
obsessive-compulsive disorder 1 | 61

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Liver and Pancreas 10 | 16,750
Respiratory system 10 | 16,393
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 5 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

GWAS Trait

Lobe attachment (rater scored) 11 | 11
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127
Serine/threonine-protein kinase SIK3 SIK3 Tchem Kinase -1.18286 18.2 0
Sulfotransferase 1C4 SULT1C4 Tbio Enzyme -1.19364 16.1 77
Sickle tail protein homolog KIAA1217 Tbio Non-IDG -2.21538 156.5 15
Coiled-coil domain-containing protein 138 CCDC138 Tdark Non-IDG 0.60 0.25 56
28S ribosomal protein S22, mitochondrial MRPS22 Tbio Non-IDG -2.42971 211.9 107
Mitochondrial 2-oxodicarboxylate carrier SLC25A21 Tbio Transporter -0.71354 3.68 112
Tumor necrosis factor receptor superfamily member EDAR EDAR Tbio Non-IDG -2.21203 161.3 194
Semaphorin-3E SEMA3E Tbio Non-IDG -1.62878 48.9 219
E3 SUMO-protein ligase RanBP2 RANBP2 Tbio Enzyme -2.24609 178.6 172