Development Level

Tbio 16 | 11,445
Tchem 4 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
increased or absent threshold ... 2 | 101
abnormal behavior 1 | 298
abnormal brain morphology 1 | 13
abnormal retina morphology 1 | 71
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased circulating serum al... 1 | 82
decreased circulating unsatura... 1 | 2
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic lethality prior to t... 1 | 278
hydroencephaly 1 | 14
hypoactivity 1 | 132
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 18 | 11,493
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
medulloblastoma, large-cell 10 | 6,241
osteosarcoma 10 | 7,950
ovarian cancer 10 | 8,520
glioblastoma 9 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
atypical teratoid / rhabdoid tumor 8 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
primitive neuroectodermal tumor 8 | 3,035
astrocytic glioma 7 | 2,597
non-small cell lung cancer 7 | 2,890
psoriasis 7 | 6,694
Breast cancer 6 | 3,578
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
group 3 medulloblastoma 6 | 4,104
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
lung cancer 6 | 4,740
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
spina bifida 6 | 1,074
subependymal giant cell astrocytoma 6 | 2,287
ulcerative colitis 6 | 1,819
Astrocytoma, Pilocytic 5 | 3,081
Cancer 5 | 2,499
Crohn's disease 5 | 321
Kidney cancer 5 | 2,613
Pick disease 5 | 1,894
adult high grade glioma 5 | 3,801
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
ependymoma 5 | 4,679
group 4 medulloblastoma 5 | 1,855
pancreatic cancer 5 | 2,398
pituitary cancer 4 | 1,972
Acquired metabolic disease 3 | 336
Alzheimer's disease 3 | 658
Carcinoma, Hepatocellular 3 | 228
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Failure to gain weight 3 | 365
Fatty liver disease 3 | 103
Gout 3 | 106
Hepatomegaly 3 | 285
Hyperglycemia 3 | 137
Liver cancer 3 | 604
Liver carcinoma 3 | 240
Obesity 3 | 678
Pediatric failure to thrive 3 | 365
Type 2 diabetes mellitus 3 | 272
Vascular disease 3 | 319
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
interstitial cystitis 3 | 2,312
maturity-onset diabetes of the young 3 | 32
medulloblastoma 3 | 720
Amyotrophic lateral sclerosis 2 | 451
Asthma 2 | 385
Atherosclerosis 2 | 291
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Blepharophimosis 2 | 70
Cardiovascular system disease 2 | 246
Cholestasis 2 | 155
Concave bridge of nose 2 | 195
Congenital deafness 2 | 185
Deafness 2 | 198
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Diarrhea 2 | 253
Down syndrome 2 | 499
Hearing Loss, Partial 2 | 185
Hypertension 2 | 396
Hypoglycemia 2 | 152
Infantile onset 2 | 238
Kidney disease 2 | 430
Lipid metabolism disorder 2 | 114
Liver disease 2 | 237
Multiple myeloma 2 | 1,332
Osteoporosis 2 | 363
Polycystic ovary syndrome 2 | 360
Waldenstrons macroglobulinemia 2 | 765
aldosterone-producing adenoma 2 | 665
cutaneous lupus erythematosus 2 | 1,057
fibroadenoma 2 | 559
hearing impairment 2 | 199
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
nephrosclerosis 2 | 333
pediatric high grade glioma 2 | 1,064
periodontitis 2 | 293
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010

Tissue

Digestive Tract 24 | 17,369
Liver and Pancreas 24 | 16,750
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Respiratory system 22 | 16,393

Target Family

Non-IDG 9 | 12,091
Enzyme 7 | 4,145
Transcription Factor 4 | 1,400
Transporter 2 | 473
Kinase 1 | 634
Nuclear Receptor 1 | 48

GWAS Trait

Liver enzyme levels (gamma-glu... 24 | 24
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
EF-hand domain-containing protein D1 EFHD1 Tbio Non-IDG -1.96673 92.2 187
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481
Phospholipid-transporting ATPase IC ATP8B1 Tbio Transporter -2.47204 273.0 19
Rho guanine nucleotide exchange factor 19 ARHGEF19 Tdark Non-IDG -0.56361 4.10 53
[F-actin]-monooxygenase MICAL3 MICAL3 Tbio Enzyme -0.76459 5.21 20
Galactoside 2-alpha-L-fucosyltransferase 2 FUT2 Tbio Enzyme -3.06062 1122.9 105
Unconventional myosin-Ib MYO1B Tbio Non-IDG -1.76878 60.8 85
Muscular LMNA-interacting protein MLIP Tdark Non-IDG -1.49078 28.4 40
Carbohydrate-responsive element-binding protein MLXIPL Tbio Transcription Factor -2.29554 206.7 235
Exocyst complex component 3-like protein 4 EXOC3L4 Tdark Non-IDG 0.48 0.25 7