Development Level

Tbio 8 | 11,445
Tchem 3 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased total body fat amoun... 2 | 207
increased lean body mass 2 | 172
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal outer ear morphology 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged kidney 1 | 14
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
microphthalmia 1 | 26
mydriasis 1 | 6
small testis 1 | 58
thin ventricular wall 1 | 24
tremors 1 | 39
vertebral transformation 1 | 12

Disease

Carcinoma 9 | 11,493
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
medulloblastoma, large-cell 7 | 6,241
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
Rheumatoid arthritis 5 | 1,191
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
oligodendroglioma 5 | 2,850
osteosarcoma 5 | 7,950
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
subependymal giant cell astrocytoma 4 | 2,287
Astrocytoma, Pilocytic 3 | 3,081
Cardiovascular system disease 3 | 246
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Adenoid Cystic Carcinoma 2 | 99
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Carcinoma, Adenoid Cystic 2 | 99
Colorectal Neoplasms 2 | 243
Coronary artery disease 2 | 268
Disease of metabolism 2 | 18
Kidney cancer 2 | 2,613
Liver disease 2 | 237
Mood Disorders 2 | 184
Obesity 2 | 678
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
active Crohn's disease 2 | 922
group 3 medulloblastoma 2 | 4,104
hepatocellular carcinoma 2 | 547
interstitial lung disease 2 | 298
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pancreatic carcinoma 2 | 562
primitive neuroectodermal tumor 2 | 3,035
urothelial carcinoma 2 | 318
Acquired metabolic disease 1 | 336
Alkaline phosphatase serum increased 1 | 29
Amelogenesis imperfecta type 1B 1 | 4
Amelogenesis imperfecta type 1E 1 | 3
Autism Spectrum Disorders 1 | 75
Autoimmune hepatitis 1 | 11
Babinski Reflex 1 | 100
Barrett's esophagus 1 | 182
Bilirubin metabolic disorder 1 | 41
Chemical and Drug Induced Liver Injury 1 | 195
Cholestasis of pregnancy 1 | 5
Common variable immunodeficiency 1 | 101
Congenital pes cavus 1 | 88
Conjugated hyperbilirubinemia 1 | 14
Crohn Disease 1 | 45
Decreased nerve conduction velocity 1 | 35
DiGeorge syndrome 1 | 47
Diabetes mellitus type 2 1 | 69
Distal amyotrophy 1 | 51
Distal sensory impairment 1 | 52
Dysarthria 1 | 192
Fatty liver disease 1 | 103
Fragile X syndrome 1 | 34
Hemolytic anemia 1 | 77
Icterus 1 | 82
Intrahepatic cholestasis 1 | 20
Keratoconjunctivitis sicca 1 | 25
Leber congenital amaurosis 1 | 69
Mastitis 1 | 48
Metabolic syndrome X 1 | 52
Mucoepidermoid carcinoma 1 | 26
Peripheral Neuropathy 1 | 134
Prevention of Cardiac Transplant Rejection 1 | 15
Prevention of Kidney Transplant Rejection 1 | 17
Prevention of Liver Transplant Rejection 1 | 15
Progressive intrahepatic cholestasis 1 | 4
Pruritus 1 | 58
Salivary Gland Neoplasms 1 | 46
Sengers syndrome 1 | 18
Sensorineural Hearing Loss (disorder) 1 | 284
Severe Recalcitrant Psoriasis 1 | 12
Spastic Quadriplegia 1 | 42
Tear film insufficiency 1 | 15
inflammatory breast cancer 1 | 286

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Liver and Pancreas 13 | 16,750
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192
Female tissues 12 | 17,400
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393

Target Family

Enzyme 6 | 4,145
Non-IDG 5 | 12,091
Epigenetic 1 | 242
Kinase 1 | 634
Transporter 1 | 473

GWAS Trait

Liver enzyme levels (alkaline ... 14 | 14
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 246 TMEM246 Tdark Non-IDG 0.00000 17
Fatty acid desaturase 2 FADS2 Tbio Enzyme -2.55411 349.6 135
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0
Galactoside 2-alpha-L-fucosyltransferase 2 FUT2 Tbio Enzyme -3.06062 1122.9 105
Bile salt export pump ABCB11 Tchem Transporter -2.84131 702.2 144
Polyamine-modulated factor 1-binding protein 1 PMFBP1 Tdark Non-IDG 0.60 0.27 68
Phosphatidylinositol-glycan-specific phospholipase D GPLD1 Tbio Enzyme -2.08209 126.8 222
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 ST3GAL4 Tbio Enzyme -2.19681 149.3 89
Tribbles homolog 1 TRIB1 Tbio Kinase -1.74370 59.4 250
Neuroblastoma breakpoint family member 3 NBPF3 Tdark Non-IDG -0.17609 1.49 37