Development Level

Tbio 12 | 11,651
Tchem 5 | 1,388
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal outer ear morphology 1 | 3
abnormal tooth morphology 1 | 24
absent startle reflex 1 | 24
anophthalmia 1 | 33
cataract 1 | 92
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
microphthalmia 1 | 26
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

Carcinoma 14 | 11,493
Cardiovascular system disease 13 | 246
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
Atherosclerosis 9 | 291
Coronary artery disease 9 | 268
Lipid metabolism disorder 9 | 114
glioblastoma 9 | 5,792
medulloblastoma, large-cell 9 | 6,241
diabetes mellitus 8 | 1,728
group 3 medulloblastoma 8 | 4,104
lung cancer 8 | 4,740
malignant mesothelioma 8 | 3,232
Obesity 7 | 678
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
psoriasis 7 | 6,694
Breast cancer 6 | 3,578
Metabolic syndrome X 6 | 52
Vascular disease 6 | 319
Hypercholesterolemia, Familial 5 | 23
Hyperlipidemia 5 | 43
Hyperlipoproteinemia Type II 5 | 12
Hypertriglyceridemia 5 | 17
Macular degeneration 5 | 65
Type 2 diabetes mellitus 5 | 272
nasopharyngeal carcinoma 5 | 1,058
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Autosomal recessive predisposition 4 | 1,442
Hypercholesterolemia 4 | 44
Hyperlipidemias 4 | 17
Liver Cirrhosis, Experimental 4 | 769
Pick disease 4 | 1,894
astrocytoma 4 | 1,146
atypical teratoid / rhabdoid tumor 4 | 5,112
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
ulcerative colitis 4 | 1,819
Acquired metabolic disease 3 | 336
Age related macular degeneration 3 | 72
Alzheimer's disease 3 | 658
Cardiovascular Diseases 3 | 59
Cerebrovascular disease 3 | 238
Dyslipidemias 3 | 27
Fatty liver disease 3 | 103
Hypertension 3 | 396
Hypertensive disease 3 | 292
Kidney cancer 3 | 2,613
Myocardial Infarction 3 | 151
Schizophrenia 3 | 1,160
Serum cholesterol raised 3 | 22
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
lung adenocarcinoma 3 | 2,716
nephrosclerosis 3 | 333
non-small cell lung cancer 3 | 2,890
Alcoholic Intoxication, Chronic 2 | 289
Amyotrophic lateral sclerosis 2 | 451
Angina Pectoris 2 | 32
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Cancer 2 | 2,499
Cognitive disorder 2 | 50
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Disease Models, Animal 2 | 155
Epilepsy 2 | 792
Heart disease 2 | 306
Hyperglycemia 2 | 137
Hypertriglyceridemia result 2 | 37
Immune system cancer 2 | 140
Kidney disease 2 | 430
Liver cancer 2 | 604
Lymphoid leukemia 2 | 160
Multiple Sclerosis 2 | 540
Myopathy 2 | 185
Pancreatitis 2 | 123
Prostatic Neoplasms 2 | 495
Seizures 2 | 596
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
chronic rhinosinusitis 2 | 512
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
inflammatory breast cancer 2 | 286
interstitial lung disease 2 | 298
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Skin and soft tissues 19 | 17,230
Blood and immune system 18 | 16,909
Male tissues 18 | 17,142
Respiratory system 18 | 16,393
Urinary Tract 18 | 16,678
Cardiovascular System 17 | 15,192
Nervous System 17 | 16,725

Target Family

Non-IDG 11 | 12,091
Enzyme 6 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634

GWAS Trait

Lipid traits 19 | 19
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin carboxyl-terminal hydrolase 1 USP1 Tchem Enzyme -1.88853 73.3 271
Tribbles homolog 1 TRIB1 Tbio Kinase -1.74370 59.4 250
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976
Kinetochore protein Spc24 SPC24 Tbio Non-IDG -1.20569 15.8 40
Hepatic triacylglycerol lipase LIPC Tchem Enzyme -2.56840 389.0 258
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein HERPUD1 Tbio Non-IDG -1.84801 68.9 188
Ryanodine receptor 2 RYR2 Tclin Ion Channel -2.92980 851.9 138
Mitochondrial import receptor subunit TOM40 homolog TOMM40 Tbio Non-IDG -2.21973 158.9 94
Apolipoprotein C-I APOC1 Tbio Non-IDG -2.39715 256.4 274
THO complex subunit 5 homolog THOC5 Tbio Non-IDG -1.14189 16.8 116