Development Level

Tbio 6 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
lung cancer 4 | 4,740
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Kidney cancer 3 | 2,613
Retinal Degeneration 3 | 106
medulloblastoma, large-cell 3 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
psoriasis 3 | 6,694
Age related macular degeneration 2 | 72
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer's disease 2 | 658
Fundus dystrophy 2 | 83
Heart disease 2 | 306
Macular degeneration 2 | 65
Myocardial Infarction 2 | 151
Neurodegenerative disease 2 | 414
Obesity 2 | 678
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
isolated microphthalmia 5 2 | 2
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
Abdominal aortic aneurysm 1 | 9
Abnormal hair whorls 1 | 5
Abnormality of the thorax 1 | 19
Absent axillary hair 1 | 5
Alcohol abuse 1 | 50
Amyloidosis 1 | 67
Antley-Bixler syndrome 1 | 16
Arteriosclerosis 1 | 11
Aspergillosis 1 | 26
Baller-Gerold syndrome 1 | 12
Blepharitis 1 | 23
Bloom syndrome 1 | 29
CD40 ligand deficiency 1 | 2
Candidiasis of mouth 1 | 5
Candidiasis of skin 1 | 6
Carotid Artery Diseases 1 | 11
Carotid stenosis 1 | 5
Cellulitis of eyelid 1 | 17
Childhood absence epilepsy 1 | 8
Coccidioidomycosis 1 | 8
Convex nasal ridge 1 | 37
Delirium 1 | 10
Dyslipidemias 1 | 27
Edema 1 | 81
Emphysema 1 | 12
Eyelid Xanthoma 1 | 5
Familial hyperlipidemia 1 | 6
Hepatolenticular Degeneration 1 | 24
Hypercholesterolemia, Familial 1 | 23
Hyperlipidemias 1 | 17
Hyperlipoproteinemia Type II 1 | 12
Hyperlipoproteinemia Type IIa 1 | 11
LATE-ONSET RETINAL DEGENERATION (disorder) 1 | 1
Lack of skin elasticity 1 | 10
Late-Onset Retinal Degeneration 1 | 1
Lens Diseases 1 | 2
Lipoatrophy 1 | 19
Long tract signs 1 | 3
Low density lipoprotein increased 1 | 8
MICROPHTHALMIA, ISOLATED 5 1 | 1
Macular Degeneration, Age-Related, 1 1 | 9
Mediastinal lymphadenopathy 1 | 10
Mesangial abnormality 1 | 2
Microphthalmia, Posterior, With Retinitis Pigmentosa, Foveoschisis, And Optic Disc Drusen 1 | 1
Multiple, subcutaneous nodules 1 | 53
NANOPHTHALMOS 2 (disorder) 1 | 1
Nanophthalmos 2 1 | 1
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Optic disk drusen 1 | 4
Oropharyngeal Candidiasis 1 | 3
Osteosclerosis 1 | 31
Pathological accumulation of air in tissues 1 | 10
Petechiae 1 | 13
Photosensitive trichothiodystrophy 1 | 30
Premature arteriosclerosis 1 | 5
Premature canities 1 | 24
Premature hardening of arteries 1 | 5
Progeria 1 | 25
Rapadilino syndrome 1 | 7
Rothmund-Thomson syndrome 1 | 19
Sleep-wake cycle disturbance 1 | 5
Slender build 1 | 14
Small hand 1 | 36
Spinocerebellar ataxia type 6 1 | 6
Stretched skin 1 | 10
Subcutaneous nodule 1 | 53
Tinea cruris 1 | 12
Warsaw breakage syndrome 1 | 11
Werner syndrome 1 | 29
White forelock 1 | 12
Xanthelasma of periocular region 1 | 5
Xanthoma 1 | 5
Xanthoma of periocular region 1 | 5

Tissue

Endocrine System 10 | 18,159
Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 5 | 12,091
Enzyme 4 | 4,145
Kinase 1 | 634

GWAS Trait

Lifespan 10 | 10
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RIMS-binding protein 2 RIMBP2 Tdark Non-IDG -0.92981 9.11 32
Membrane frizzled-related protein MFRP Tbio Non-IDG -2.04418 60.6 209
Complement C1q tumor necrosis factor-related protein 5 C1QTNF5 Tbio Non-IDG -0.39794 1.27 209
Protein NRDE2 homolog NRDE2 Tdark Non-IDG -0.09691 1.25 18
Hydroxylysine kinase HYKK Tbio Enzyme -0.94105 7.02 28
Serine/threonine-protein kinase tousled-like 2 TLK2 Tchem Kinase -0.95456 10.1 210
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976
Werner syndrome ATP-dependent helicase WRN Tbio Enzyme -2.73759 569.7 210
Enoyl-CoA hydratase, mitochondrial ECHS1 Tbio Enzyme -1.69637 49.5 162
Lanosterol 14-alpha demethylase CYP51A1 Tchem Enzyme -2.75707 588.4 158