Development Level

Tbio 53 | 11,651
Tdark 17 | 6,593
Tchem 6 | 1,388
Tclin 2 | 612

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 4 | 979
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
abnormal locomotor activation 2 | 16
abnormal startle reflex 2 | 15
decreased body weight 2 | 161
decreased circulating iron lev... 2 | 32
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
increased blood urea nitrogen ... 2 | 48
increased circulating amylase ... 2 | 25
increased startle reflex 2 | 112
limb grasping 2 | 41
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal heart morphology 1 | 162
abnormal testis morphology 1 | 43
decreased blood urea nitrogen ... 1 | 51
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased body weight 1 | 25
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 57 | 11,493
ovarian cancer 42 | 8,520
medulloblastoma, large-cell 37 | 6,241
atypical teratoid / rhabdoid tumor 36 | 5,112
glioblastoma 35 | 5,792
osteosarcoma 33 | 7,950
ependymoma 32 | 4,679
adult high grade glioma 27 | 3,801
Kidney cancer 25 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
Breast cancer 22 | 3,578
lung carcinoma 22 | 2,843
pancreatic cancer 22 | 2,398
psoriasis 22 | 6,694
group 3 medulloblastoma 21 | 4,104
lung cancer 21 | 4,740
primitive neuroectodermal tumor 21 | 3,035
interstitial cystitis 20 | 2,312
lung adenocarcinoma 20 | 2,716
non-small cell lung cancer 20 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
malignant mesothelioma 19 | 3,232
oligodendroglioma 19 | 2,850
Astrocytoma, Pilocytic 17 | 3,081
astrocytic glioma 16 | 2,597
subependymal giant cell astrocytoma 16 | 2,287
ulcerative colitis 16 | 1,819
invasive ductal carcinoma 14 | 2,951
Cancer 13 | 2,499
Liver cancer 12 | 604
pituitary cancer 11 | 1,972
Pick disease 10 | 1,894
Melanoma 9 | 711
Rheumatoid arthritis 9 | 1,191
adrenocortical carcinoma 9 | 1,428
Intellectual disability 8 | 1,016
Skin cancer 8 | 469
cystic fibrosis 8 | 1,696
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
diabetes mellitus 7 | 1,728
ductal carcinoma in situ 7 | 1,745
medulloblastoma 7 | 720
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Bipolar Disorder 6 | 666
Colorectal Neoplasms 6 | 243
astrocytoma 6 | 1,146
group 4 medulloblastoma 6 | 1,855
primary pancreatic ductal adenocarcinoma 6 | 1,109
Atopic dermatitis 5 | 952
Duchenne muscular dystrophy 5 | 601
Endometrial cancer 5 | 311
Endometriosis 5 | 540
Lymphoid leukemia 5 | 160
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
acute quadriplegic myopathy 5 | 1,158
aldosterone-producing adenoma 5 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
dermatomyositis 5 | 966
fibroadenoma 5 | 559
gastric carcinoma 5 | 807
nasopharyngeal carcinoma 5 | 1,058
pediatric high grade glioma 5 | 1,064
spina bifida 5 | 1,074
Acquired metabolic disease 4 | 336
Anemia 4 | 365
Attention deficit hyperactivity disorder 4 | 278
Autistic Disorder 4 | 364
Autosomal recessive predisposition 4 | 1,442
Immune system cancer 4 | 140
Ovarian Neoplasms 4 | 102
Vascular disease 4 | 319
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
chronic rhinosinusitis 4 | 512
mucosa-associated lymphoid tissue lymphoma 4 | 484
ovarian neoplasm 4 | 99
tuberculosis 4 | 2,010
tuberculosis and treatment for 6 months 4 | 409
Adenoma 3 | 167
Asthma 3 | 385
Autism spectrum disorder 3 | 101
Depressive disorder 3 | 409
Kidney disease 3 | 430
Polycystic ovary syndrome 3 | 360
Prostate cancer 3 | 175
Prostatic Neoplasms 3 | 495
Stomach Neoplasms 3 | 300
Unipolar Depression 3 | 250
cutaneous lupus erythematosus 3 | 1,057
gastric cancer 3 | 459
hepatocellular carcinoma 3 | 547
juvenile dermatomyositis 3 | 1,187
pancreatic carcinoma 3 | 562
sonic hedgehog group medulloblastoma 3 | 467
substance-related disorder 3 | 162
urothelial carcinoma 3 | 318

Tissue

Male tissues 75 | 17,142
Endocrine System 74 | 18,159
Digestive Tract 72 | 17,369
Skin and soft tissues 72 | 17,230
Urinary Tract 72 | 16,678
Blood and immune system 71 | 16,909
Female tissues 71 | 17,400
Liver and Pancreas 71 | 16,750
Nervous System 70 | 16,725
Respiratory system 68 | 16,393
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 41 | 12,091
Enzyme 20 | 4,145
Transcription Factor 5 | 1,400
Kinase 4 | 634
Transporter 3 | 473
GPCR 2 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

GWAS Trait

Late-onset Alzheimer's disease 78 | 78
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cilia- and flagella-associated protein 74 CFAP74 Tdark Non-IDG 0.38 0.16 21
Dynein heavy chain 6, axonemal DNAH6 Tbio Non-IDG -0.53057 4.17 18
Leucine-rich repeats and immunoglobulin-like domains protein 3 LRIG3 Tbio Non-IDG -1.14921 15.6 94
Oxidative stress-responsive serine-rich protein 1 OSER1 Tdark Non-IDG -0.30103 2.00 47
Rho GTPase-activating protein 7 DLC1 Tbio Enzyme -1.93185 106.7 137
E3 ubiquitin-protein ligase ZNRF4 ZNRF4 Tbio Non-IDG -0.74036 5.54 94
General transcription factor IIH subunit 3 GTF2H3 Tbio Non-IDG -0.87291 7.21 78
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Ras association domain-containing protein 5 RASSF5 Tbio Non-IDG -1.81149 71.3 155
Putative methyltransferase-like protein 21E pseudogene METTL21EP Tdark Enzyme 0.00000 0