Development Level

Tbio 50 | 11,445
Tchem 6 | 1,598
Tclin 4 | 613
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal behavior 3 | 298
increased circulating alkaline... 3 | 122
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating serum al... 2 | 82
decreased total body fat amoun... 2 | 207
hyperactivity 2 | 148
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal joint morphology 1 | 23
abnormal outer ear morphology 1 | 3
abnormal radius morphology 1 | 8
abnormal scapula morphology 1 | 3
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
anophthalmia 1 | 33
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
kyphosis 1 | 5
microphthalmia 1 | 26
tremors 1 | 39

Disease

Carcinoma 50 | 11,493
osteosarcoma 33 | 7,950
ovarian cancer 32 | 8,520
psoriasis 31 | 6,694
medulloblastoma, large-cell 24 | 6,241
lung cancer 22 | 4,740
glioblastoma 20 | 5,792
Cardiovascular system disease 19 | 246
Kidney cancer 17 | 2,613
Breast cancer 15 | 3,578
Lipid metabolism disorder 14 | 114
atypical teratoid / rhabdoid tumor 14 | 5,112
diabetes mellitus 14 | 1,728
ductal carcinoma in situ 13 | 1,745
interstitial cystitis 13 | 2,312
malignant mesothelioma 13 | 3,232
Cancer 12 | 2,499
Coronary artery disease 12 | 268
group 3 medulloblastoma 12 | 4,104
Atherosclerosis 11 | 291
adult high grade glioma 11 | 3,801
ependymoma 11 | 4,679
pancreatic cancer 11 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Anemia 10 | 365
Autosomal recessive predisposition 10 | 1,442
Obesity 10 | 678
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
oligodendroglioma 10 | 2,850
Alzheimer's disease 9 | 658
Liver cancer 9 | 604
Pick disease 9 | 1,894
Sickle Cell Anemia 9 | 53
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
non-small cell lung cancer 9 | 2,890
ulcerative colitis 9 | 1,819
Intellectual disability 8 | 1,016
Schizophrenia 8 | 1,160
group 4 medulloblastoma 8 | 1,855
Bilirubin metabolic disorder 7 | 41
Hypercholesterolemia 7 | 44
Pericholangitis 7 | 8
Vascular disease 7 | 319
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
esophageal adenocarcinoma 7 | 737
tuberculosis 7 | 2,010
Cerebrovascular disease 6 | 238
Hyperlipidemia 6 | 43
Metabolic syndrome X 6 | 52
breast carcinoma 6 | 1,638
juvenile dermatomyositis 6 | 1,187
lung adenocarcinoma 6 | 2,716
non primary Sjogren syndrome sicca 6 | 891
primitive neuroectodermal tumor 6 | 3,035
spina bifida 6 | 1,074
Atopic dermatitis 5 | 952
Bipolar Disorder 5 | 666
Coronary Disease 5 | 25
Dull intelligence 5 | 645
Dyslipidemias 5 | 27
Epilepsy 5 | 792
Familial hypercholesterolemia - homozygous 5 | 7
Fatty liver disease 5 | 103
Hypercholesterolemia, Familial 5 | 23
Low intelligence 5 | 645
Macular degeneration 5 | 65
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Myocardial Infarction 5 | 151
Poor school performance 5 | 645
Type 2 diabetes mellitus 5 | 272
acute myeloid leukemia 5 | 783
acute quadriplegic myopathy 5 | 1,158
adrenocortical carcinoma 5 | 1,428
Arcus Senilis 4 | 11
Astrocytoma, Pilocytic 4 | 3,081
Attention deficit hyperactivity disorder 4 | 278
Coronary heart disease 4 | 16
Diarrhea 4 | 253
Endometrial cancer 4 | 311
Hypertensive disease 4 | 292
Kidney disease 4 | 430
Melanoma 4 | 711
Prenatal onset 4 | 139
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
chronic rhinosinusitis 4 | 512
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Digestive Tract 63 | 17,369
Liver and Pancreas 62 | 16,750
Skin and soft tissues 62 | 17,230
Urinary Tract 60 | 16,678
Endocrine System 58 | 18,159
Female tissues 58 | 17,400
Male tissues 58 | 17,142
Blood and immune system 56 | 16,909
Nervous System 53 | 16,725
Respiratory system 53 | 16,393
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 34 | 12,091
Enzyme 23 | 4,145
Kinase 3 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344

GWAS Trait

LDL cholesterol levels 64 | 64
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CKLF-like MARVEL transmembrane domain-containing protein 6 CMTM6 Tdark Non-IDG -0.56950 2.80 85
Myotubularin-related protein 3 MTMR3 Tbio Enzyme -1.05980 10.7 33
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tbio Enzyme -1.93041 83.4 177
Fatty acid desaturase 2 FADS2 Tbio Enzyme -2.55411 349.6 135
Tyrosine-protein kinase FRK FRK Tchem Kinase -1.68365 49.2 394
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139
GPI mannosyltransferase 2 PIGV Tbio Enzyme -1.07565 13.4 71
Cadherin EGF LAG seven-pass G-type receptor 2 CELSR2 Tbio GPCR -1.22995 16.7 139
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0
Phosphoribosylformylglycinamidine synthase PFAS Tbio Enzyme -2.83741 653.1 88