Development Level

Tbio 74 | 11,445
Tdark 14 | 6,588
Tchem 13 | 1,598
Tclin 9 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
decreased total body fat amoun... 4 | 207
abnormal behavior 3 | 298
cataract 3 | 92
decreased circulating serum al... 3 | 82
embryonic lethality prior to t... 3 | 278
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased mean corpuscular vol... 2 | 79
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal neural tube morpholog... 1 | 12
abnormal outer ear morphology 1 | 3
abnormal pelvic girdle bone mo... 1 | 12
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased circulating unsatura... 1 | 1
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
prolonged PQ interval 1 | 5
prolonged ST segment 1 | 36
small testis 1 | 58
tremors 1 | 39
vertebral transformation 1 | 12

Disease

Carcinoma 88 | 11,493
osteosarcoma 54 | 7,950
ovarian cancer 51 | 8,520
psoriasis 46 | 6,694
medulloblastoma, large-cell 37 | 6,241
Cardiovascular system disease 36 | 246
lung cancer 32 | 4,740
Kidney cancer 30 | 2,613
glioblastoma 26 | 5,792
Lipid metabolism disorder 25 | 114
diabetes mellitus 24 | 1,728
Breast cancer 23 | 3,578
malignant mesothelioma 23 | 3,232
atypical teratoid / rhabdoid tumor 22 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
Atherosclerosis 21 | 291
ductal carcinoma in situ 21 | 1,745
group 3 medulloblastoma 21 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
Coronary artery disease 20 | 268
ependymoma 20 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
Cancer 19 | 2,499
interstitial cystitis 19 | 2,312
invasive ductal carcinoma 19 | 2,951
pancreatic cancer 19 | 2,398
Obesity 18 | 678
Schizophrenia 17 | 1,160
adult high grade glioma 17 | 3,801
Autosomal recessive predisposition 15 | 1,442
primitive neuroectodermal tumor 15 | 3,035
Liver cancer 13 | 604
Pick disease 13 | 1,894
breast carcinoma 13 | 1,638
group 4 medulloblastoma 13 | 1,855
lung carcinoma 13 | 2,843
oligodendroglioma 13 | 2,850
Alzheimer's disease 12 | 658
Anemia 12 | 365
astrocytic glioma 12 | 2,597
non-small cell lung cancer 12 | 2,890
tuberculosis 12 | 2,010
Cerebrovascular disease 11 | 238
Fatty liver disease 11 | 103
Atopic dermatitis 10 | 952
Hypercholesterolemia 10 | 44
Intellectual disability 10 | 1,016
Kidney disease 10 | 430
Type 2 diabetes mellitus 10 | 272
astrocytoma 10 | 1,146
spina bifida 10 | 1,074
Hypertension 9 | 396
Liver disease 9 | 237
Prostatic Neoplasms 9 | 495
Sickle Cell Anemia 9 | 53
adrenocortical carcinoma 9 | 1,428
esophageal adenocarcinoma 9 | 737
lung adenocarcinoma 9 | 2,716
mucosa-associated lymphoid tissue lymphoma 9 | 484
pituitary cancer 9 | 1,972
ulcerative colitis 9 | 1,819
Bilirubin metabolic disorder 8 | 41
Chemical and Drug Induced Liver Injury 8 | 195
Dyslipidemias 8 | 27
Heart disease 8 | 306
Hypertensive disease 8 | 292
Metabolic syndrome X 8 | 52
Neurodegenerative disease 8 | 414
Vascular disease 8 | 319
Astrocytoma, Pilocytic 7 | 3,081
Bipolar Disorder 7 | 666
Coronary Disease 7 | 25
Dull intelligence 7 | 645
Hyperlipidemia 7 | 43
Low intelligence 7 | 645
Melanoma 7 | 711
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Myocardial Infarction 7 | 151
Pericholangitis 7 | 8
Poor school performance 7 | 645
acute quadriplegic myopathy 7 | 1,158
juvenile dermatomyositis 7 | 1,187
pancreatic carcinoma 7 | 562
subependymal giant cell astrocytoma 7 | 2,287
Coronary heart disease 6 | 16
Epilepsy 6 | 792
Hypercholesterolemia, Familial 6 | 23
Liver Cirrhosis, Experimental 6 | 769
Multiple Sclerosis 6 | 540
Muscle hypotonia 6 | 571
Rheumatoid arthritis 6 | 1,191
Thrombocytopenia 6 | 197
active ulcerative colitis 6 | 764
acute myeloid leukemia 6 | 783
colon cancer 6 | 1,478
Multiple myeloma 5 | 1,332
dermatomyositis 5 | 966
primary pancreatic ductal adenocarcinoma 5 | 1,109

Tissue

Digestive Tract 107 | 17,369
Liver and Pancreas 106 | 16,750
Skin and soft tissues 105 | 17,230
Endocrine System 103 | 18,159
Female tissues 102 | 17,400
Male tissues 100 | 17,142
Urinary Tract 100 | 16,678
Blood and immune system 96 | 16,909
Nervous System 96 | 16,725
Respiratory system 93 | 16,393
Cardiovascular System 81 | 15,192

Target Family

Non-IDG 56 | 12,091
Enzyme 31 | 4,145
Transcription Factor 8 | 1,400
Kinase 4 | 634
Transporter 4 | 473
Nuclear Receptor 3 | 48
Epigenetic 2 | 242
GPCR 1 | 408
Ion Channel 1 | 344

GWAS Trait

LDL cholesterol 110 | 110
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CKLF-like MARVEL transmembrane domain-containing protein 6 CMTM6 Tdark Non-IDG -0.56950 2.80 85
Myotubularin-related protein 3 MTMR3 Tbio Enzyme -1.05980 10.7 33
E3 ubiquitin-protein ligase RNF130 RNF130 Tbio Enzyme -2.20315 148.8 86
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tbio Enzyme -1.93041 83.4 177
Fatty acid desaturase 2 FADS2 Tbio Enzyme -2.55411 349.6 135
Tyrosine-protein kinase FRK FRK Tchem Kinase -1.68365 49.2 394
Zinc finger protein 329 ZNF329 Tdark Transcription Factor 0.30 0.50 119
Zinc finger protein Gfi-1 GFI1 Tbio Transcription Factor -2.20783 172.7 176
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139
GPI mannosyltransferase 2 PIGV Tbio Enzyme -1.07565 13.4 71