Development Level

Tbio 105 | 11,445
Tdark 36 | 6,588
Tchem 15 | 1,598
Tclin 6 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal heart morphology 4 | 162
decreased body weight 4 | 161
decreased erythrocyte cell num... 4 | 62
enlarged heart 4 | 210
preweaning lethality, incomple... 4 | 499
thrombocytopenia 4 | 56
abnormal embryo size 3 | 220
decreased bone mineral content 3 | 151
decreased grip strength 3 | 116
embryonic lethality prior to t... 3 | 278
increased bone mineral content 3 | 108
increased mean corpuscular hem... 3 | 96
increased startle reflex 3 | 112
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal locomotor activation 2 | 16
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased exploration in new e... 2 | 11
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
increased bone mineral density 2 | 72
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
male infertility 2 | 123
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal defecation 1 | 1
abnormal eye morphology 1 | 68
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
abnormal vocalization 1 | 21
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating total pr... 1 | 49
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased kidney weight 1 | 1
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
dilated heart left ventricle 1 | 11
enlarged kidney 1 | 14
enlarged testis 1 | 6
female infertility 1 | 60
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased T cell number 1 | 6
increased body weight 1 | 25
increased cardiac stroke volum... 1 | 1
increased caudal vertebrae num... 1 | 7
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
thick skin 1 | 4
vertebral transformation 1 | 12

Disease

Carcinoma 102 | 11,493
ovarian cancer 75 | 8,520
psoriasis 70 | 6,694
osteosarcoma 67 | 7,950
medulloblastoma, large-cell 64 | 6,241
glioblastoma 62 | 5,792
ependymoma 53 | 4,679
atypical teratoid / rhabdoid tumor 52 | 5,112
lung cancer 50 | 4,740
Breast cancer 45 | 3,578
adult high grade glioma 42 | 3,801
Astrocytoma, Pilocytic 41 | 3,081
malignant mesothelioma 40 | 3,232
group 3 medulloblastoma 39 | 4,104
Kidney cancer 38 | 2,613
subependymal giant cell astrocytoma 38 | 2,287
invasive ductal carcinoma 36 | 2,951
oligodendroglioma 33 | 2,850
astrocytic glioma 32 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
lung carcinoma 28 | 2,843
non-small cell lung cancer 28 | 2,890
pancreatic cancer 28 | 2,398
primitive neuroectodermal tumor 28 | 3,035
Cancer 27 | 2,499
Schizophrenia 25 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
interstitial cystitis 24 | 2,312
lung adenocarcinoma 24 | 2,716
pituitary cancer 24 | 1,972
ulcerative colitis 24 | 1,819
cystic fibrosis 23 | 1,696
ductal carcinoma in situ 23 | 1,745
group 4 medulloblastoma 21 | 1,855
colon cancer 20 | 1,478
tuberculosis 20 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Melanoma 17 | 711
Pick disease 17 | 1,894
diabetes mellitus 17 | 1,728
acute quadriplegic myopathy 16 | 1,158
pediatric high grade glioma 16 | 1,064
adrenocortical carcinoma 15 | 1,428
breast carcinoma 15 | 1,638
Asthma 14 | 385
Liver cancer 14 | 604
Rheumatoid arthritis 14 | 1,191
cutaneous lupus erythematosus 14 | 1,057
primary pancreatic ductal adenocarcinoma 14 | 1,109
Crohn's disease 13 | 321
Endometrial cancer 13 | 311
juvenile dermatomyositis 13 | 1,187
nasopharyngeal carcinoma 13 | 1,058
primary Sjogren syndrome 13 | 735
spina bifida 13 | 1,074
Bipolar Disorder 12 | 666
Skin cancer 12 | 469
active ulcerative colitis 12 | 764
esophageal adenocarcinoma 12 | 737
Atopic dermatitis 10 | 952
Autosomal recessive predisposition 10 | 1,442
Major Depressive Disorder 10 | 301
Multiple Sclerosis 10 | 540
Unipolar Depression 10 | 250
Allergic hypersensitivity disease 9 | 126
Alzheimer's disease 9 | 658
Autistic Disorder 9 | 364
Obesity 9 | 678
active Crohn's disease 9 | 922
astrocytoma 9 | 1,146
chronic rhinosinusitis 9 | 512
dermatomyositis 9 | 966
urothelial carcinoma 9 | 318
Acquired metabolic disease 8 | 336
Hypereosinophilic syndrome 8 | 71
Intellectual disability 8 | 1,016
Liver Cirrhosis, Experimental 8 | 769
sarcoidosis 8 | 370
Allergic rhinitis 7 | 94
Cardiovascular system disease 7 | 246
Dermatitis 7 | 157
Duchenne muscular dystrophy 7 | 601
Epilepsy 7 | 792
Inflammatory bowel disease 7 | 151
Parkinson's disease 7 | 392
Pneumonia 7 | 174
Polycystic ovary syndrome 7 | 360
Type 2 diabetes mellitus 7 | 272
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
gastric carcinoma 7 | 807
medulloblastoma 7 | 720
pancreatic carcinoma 7 | 562
Hypersensitivity reaction type II disease 6 | 253
Mental Depression 6 | 333
Vascular disease 6 | 319
Waldenstrons macroglobulinemia 6 | 765
acute myeloid leukemia 6 | 783
fibroadenoma 6 | 559
hepatocellular carcinoma 6 | 547

Tissue

Endocrine System 152 | 18,159
Digestive Tract 146 | 17,369
Male tissues 146 | 17,142
Female tissues 145 | 17,400
Skin and soft tissues 142 | 17,230
Blood and immune system 141 | 16,909
Nervous System 136 | 16,725
Urinary Tract 136 | 16,678
Liver and Pancreas 135 | 16,750
Respiratory system 129 | 16,393
Cardiovascular System 122 | 15,192

Target Family

Non-IDG 100 | 12,091
Enzyme 36 | 4,145
Transcription Factor 13 | 1,400
Kinase 6 | 634
Transporter 3 | 473
GPCR 2 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344

GWAS Trait

Itch intensity from mosquito b... 162 | 162
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spermatogenesis-associated serine-rich protein 1 SPATS1 Tbio Non-IDG -1.08230 11.0 86
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
Extracellular matrix protein FRAS1 FRAS1 Tbio Non-IDG -1.51346 36.5 22
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Ras-related protein Rab-20 RAB20 Tbio Enzyme -0.97781 11.5 171
Pleckstrin homology-like domain family A member 3 PHLDA3 Tbio Non-IDG -0.83900 8.89 101
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127
Neurturin NRTN Tbio Non-IDG -2.21792 170.4 331
Protein fem-1 homolog A FEM1A Tbio Non-IDG -0.81569 7.92 118
Limbic system-associated membrane protein LSAMP Tbio Non-IDG -1.72744 52.8 72