Development Level

Tbio 15 | 11,651
Tchem 3 | 1,388
Tdark 3 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
enlarged heart 1 | 210
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
prenatal lethality 1 | 28
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 17 | 11,493
ovarian cancer 12 | 8,520
lung cancer 11 | 4,740
osteosarcoma 11 | 7,950
psoriasis 10 | 6,694
medulloblastoma, large-cell 9 | 6,241
glioblastoma 8 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
pituitary cancer 7 | 1,972
Astrocytoma, Pilocytic 6 | 3,081
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
non-small cell lung cancer 6 | 2,890
Cancer 5 | 2,499
Kidney cancer 5 | 2,613
Schizophrenia 5 | 1,160
atypical teratoid / rhabdoid tumor 5 | 5,112
lung adenocarcinoma 5 | 2,716
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Coronary artery disease 4 | 268
Multiple myeloma 4 | 1,332
Pick disease 4 | 1,894
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
mucosa-associated lymphoid tissue lymphoma 4 | 484
oligodendroglioma 4 | 2,850
Brain infarction 3 | 22
Cerebrovascular disease 3 | 238
Rheumatoid arthritis 3 | 1,191
active Crohn's disease 3 | 922
gastric carcinoma 3 | 807
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
Adult onset 2 | 82
Alcoholic Intoxication, Chronic 2 | 289
Alopecia universalis 2 | 16
Amyotrophic lateral sclerosis 2 | 451
Asthma 2 | 385
Atrial Fibrillation 2 | 124
Barrett's esophagus 2 | 182
Broad flat nasal bridge 2 | 236
Cerebrovascular accident 2 | 63
Corneal disease 2 | 31
Craniofacial Abnormalities 2 | 151
Crohn's disease 2 | 321
Duchenne muscular dystrophy 2 | 601
Hepatomegaly 2 | 285
Highly variable severity 2 | 157
Hypodontia 2 | 81
Hypotrophic midface 2 | 105
Liver Cirrhosis, Experimental 2 | 769
Mental Depression 2 | 333
Midface retrusion 2 | 105
Mood Disorders 2 | 184
Myocardial Infarction 2 | 151
Nasal bridge wide 2 | 236
Neurodegenerative disease 2 | 414
Osteoporosis 2 | 363
Penile hypospadias 2 | 106
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Slow progression 2 | 89
Small midface 2 | 105
Stroke 2 | 33
Variable expressivity 2 | 157
Vascular disease 2 | 319
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
chronic rhinosinusitis 2 | 512
cystic fibrosis and chronic rhinosinusitis 2 | 214
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
limb girdle muscular dystrophy 2B 2 | 40
medulloblastoma 2 | 720
non-small cell lung carcinoma 2 | 317
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
primitive neuroectodermal tumor 2 | 3,035
sarcoidosis 2 | 370
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Endocrine System 22 | 18,159
Skin and soft tissues 22 | 17,230
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Urinary Tract 21 | 16,678
Blood and immune system 19 | 16,909

Target Family

Enzyme 8 | 4,145
Non-IDG 8 | 12,091
Epigenetic 3 | 242
Transcription Factor 2 | 1,400
Kinase 1 | 634
Transporter 1 | 473

GWAS Trait

Ischemic stroke 23 | 23
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-(1,6)-fucosyltransferase FUT8 Tbio Enzyme -1.93724 92.9 145
Pituitary homeobox 2 PITX2 Tbio Transcription Factor -2.67290 480.0 220
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Prelamin-A/C LMNA Tbio Non-IDG -3.03952 1089.9 1005
Ubiquitin carboxyl-terminal hydrolase 38 USP38 Tbio Enzyme -0.20218 1.29 83
MAP kinase-activated protein kinase 5 MAPKAPK5 Tchem Kinase -1.87360 78.8 436
Ras and EF-hand domain-containing protein RASEF Tbio Non-IDG -0.72232 5.98 63
Histone acetyltransferase KAT2B KAT2B Tchem Epigenetic -2.62847 372.0 331
N-alpha-acetyltransferase 25, NatB auxiliary subunit NAA25 Tbio Enzyme -1.07341 11.8 72
Tumor necrosis factor receptor superfamily member 21 TNFRSF21 Tbio Non-IDG -2.23109 178.7 413