Development Level

Tbio 45 | 11,445
Tclin 3 | 613
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal eye morphology 3 | 68
decreased lymphocyte cell numb... 3 | 83
increased monocyte cell number 3 | 63
preweaning lethality, incomple... 3 | 499
abnormal coat-hair pigmentatio... 2 | 64
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased circulating bilirubi... 2 | 19
decreased vertical activity 2 | 208
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
abnormal cecum morphology 1 | 7
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal incisor morphology 1 | 4
abnormal kidney morphology 1 | 65
abnormal radius morphology 1 | 8
abnormal sensory capabilities-... 1 | 8
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vitreous body morphol... 1 | 10
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
enlarged cecum 1 | 5
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged kidney 1 | 14
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating aspartat... 1 | 15
increased circulating iron lev... 1 | 30
increased leukocyte cell numbe... 1 | 47
small spleen 1 | 19
small testis 1 | 58
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 40 | 11,493
ovarian cancer 38 | 8,520
glioblastoma 26 | 5,792
osteosarcoma 26 | 7,950
medulloblastoma, large-cell 25 | 6,241
ependymoma 23 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
atypical teratoid / rhabdoid tumor 21 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
lung cancer 21 | 4,740
Astrocytoma, Pilocytic 19 | 3,081
adult high grade glioma 19 | 3,801
psoriasis 19 | 6,694
Breast cancer 18 | 3,578
lung carcinoma 18 | 2,843
Kidney cancer 17 | 2,613
malignant mesothelioma 17 | 3,232
pancreatic cancer 17 | 2,398
pituitary cancer 17 | 1,972
invasive ductal carcinoma 16 | 2,951
group 3 medulloblastoma 15 | 4,104
non-small cell lung cancer 15 | 2,890
lung adenocarcinoma 14 | 2,716
ulcerative colitis 14 | 1,819
astrocytic glioma 13 | 2,597
juvenile dermatomyositis 13 | 1,187
oligodendroglioma 13 | 2,850
primitive neuroectodermal tumor 13 | 3,035
Acquired metabolic disease 12 | 336
Cancer 12 | 2,499
Pick disease 12 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
acute quadriplegic myopathy 11 | 1,158
dermatomyositis 11 | 966
subependymal giant cell astrocytoma 11 | 2,287
breast carcinoma 10 | 1,638
group 4 medulloblastoma 10 | 1,855
primary pancreatic ductal adenocarcinoma 10 | 1,109
Autosomal recessive predisposition 9 | 1,442
cystic fibrosis 9 | 1,696
diabetes mellitus 9 | 1,728
interstitial cystitis 9 | 2,312
Liver cancer 8 | 604
Rheumatoid arthritis 8 | 1,191
colon cancer 8 | 1,478
Amyotrophic lateral sclerosis 7 | 451
Duchenne muscular dystrophy 7 | 601
ductal carcinoma in situ 7 | 1,745
gastric carcinoma 7 | 807
tuberculosis 7 | 2,010
Glaucoma 6 | 239
Melanoma 6 | 711
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
spina bifida 6 | 1,074
Acquired scoliosis 5 | 281
Byzanthine arch palate 5 | 194
Corneal disease 5 | 31
Curvature of spine 5 | 282
Liver Cirrhosis, Experimental 5 | 769
Obesity 5 | 678
Schizophrenia 5 | 1,160
astrocytoma 5 | 1,146
limb girdle muscular dystrophy 2A 5 | 213
nasopharyngeal carcinoma 5 | 1,058
pancreatic carcinoma 5 | 562
urothelial carcinoma 5 | 318
Alzheimer's disease 4 | 658
Atrial Fibrillation 4 | 124
Becker muscular dystrophy 4 | 191
Coronary artery disease 4 | 268
Down syndrome 4 | 499
Glaucoma, Open-Angle 4 | 11
Highly variable severity 4 | 157
Hyperhidrosis disorder 4 | 81
Hypertension 4 | 396
Hypertensive disease 4 | 292
Increased sweating 4 | 81
Keratoconus 4 | 113
Neonatal Hypotonia 4 | 64
Reduced fetal movement 4 | 51
Skin cancer 4 | 469
Sweating 4 | 81
Type 2 diabetes mellitus 4 | 272
Variable expressivity 4 | 157
adrenocortical carcinoma 4 | 1,428
esophageal adenocarcinoma 4 | 737
mucosa-associated lymphoid tissue lymphoma 4 | 484
non primary Sjogren syndrome sicca 4 | 891
posterior fossa group A ependymoma 4 | 468
Arthritis, Juvenile 3 | 126
Juvenile arthritis 3 | 126
Kidney disease 3 | 430
Pancreatic Neoplasm 3 | 85
Prostatic Neoplasms 3 | 495
active Crohn's disease 3 | 922
fibroadenoma 3 | 559
medulloblastoma 3 | 720
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 49 | 18,159
Female tissues 49 | 17,400
Digestive Tract 48 | 17,369
Male tissues 48 | 17,142
Nervous System 48 | 16,725
Liver and Pancreas 47 | 16,750
Respiratory system 47 | 16,393
Skin and soft tissues 47 | 17,230
Urinary Tract 47 | 16,678
Blood and immune system 46 | 16,909
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 27 | 12,091
Enzyme 11 | 4,145
Transcription Factor 8 | 1,400
Ion Channel 2 | 344
GPCR 1 | 408
Transporter 1 | 473

GWAS Trait

Intraocular pressure 50 | 50
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
Tensin-1 TNS1 Tbio Non-IDG -2.74141 354.5 133
A disintegrin and metalloproteinase with thrombospondin motifs 8 ADAMTS8 Tbio Enzyme -1.14483 14.5 153
Zinc transporter 8 SLC30A8 Tbio Transporter -2.20313 168.0 122
Zinc finger protein GLIS3 GLIS3 Tbio Transcription Factor -1.36377 28.8 63
Collagen alpha-1(VI) chain COL6A1 Tbio Non-IDG -2.03348 104.7 204