Development Level

Tbio 18 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal sensory capabilities-... 1 | 8
abnormal spleen morphology 1 | 55
abnormal vitreous body morphol... 1 | 10
absent vibrissae 1 | 12
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
female infertility 1 | 60
increased bone mineral content 1 | 108
increased or absent threshold ... 1 | 101
long tibia 1 | 25
male infertility 1 | 123
small adrenal glands 1 | 16

Disease

Carcinoma 16 | 11,493
ovarian cancer 12 | 8,520
psoriasis 9 | 6,694
Breast cancer 8 | 3,578
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
Kidney cancer 7 | 2,613
atypical teratoid / rhabdoid tumor 7 | 5,112
osteosarcoma 7 | 7,950
Astrocytoma, Pilocytic 6 | 3,081
lung carcinoma 6 | 2,843
medulloblastoma, large-cell 6 | 6,241
adult high grade glioma 5 | 3,801
group 3 medulloblastoma 5 | 4,104
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
primitive neuroectodermal tumor 5 | 3,035
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
subependymal giant cell astrocytoma 4 | 2,287
Epilepsy 3 | 792
Multiple myeloma 3 | 1,332
Seizures 3 | 596
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
lung adenocarcinoma 3 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Amyotrophic lateral sclerosis 2 | 451
Hyperreflexia 2 | 209
Kidney disease 2 | 430
Liver cancer 2 | 604
Pick disease 2 | 1,894
Spinal muscular atrophy 2 | 34
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
medulloblastoma 2 | 720
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
substance-related disorder 2 | 162
tuberculosis and treatment for 6 months 2 | 409
Abnormal ocular motility 1 | 19
Acquired metabolic disease 1 | 336
Atrophy of cerebellum 1 | 103
Autistic Disorder 1 | 364
Bradykinesia 1 | 34
Cardiovascular system disease 1 | 246
Celiac disease 1 | 116
Cerebellar degeneration 1 | 103
Congenital dilatation of ureter 1 | 1
Congenital hydronephrosis 1 | 1
Congenital hypoplasia of kidney 1 | 32
Cystic renal dysplasia 1 | 1
Death in early childhood 1 | 82
Death in infancy 1 | 82
Dilatation of ureter 1 | 15
Encephalopathies 1 | 43
Flank Pain 1 | 1
Fuchs' endothelial dystrophy 1 | 24
Gait Ataxia 1 | 51
Gliosis 1 | 56
Hereditary spherocytosis type 4 1 | 18
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Holt-Oram syndrome 1 | 12
Hydronephrosis 1 | 89
Hyperactive behavior 1 | 91
Infertility 1 | 188
Infratentorial atrophy 1 | 103
Lethargy 1 | 77
Liver Cirrhosis, Experimental 1 | 769
Mammary Neoplasms, Experimental 1 | 154
Multicystic renal dysplasia, bilateral 1 | 2
Mycobacterium avium complex disease 1 | 11
Myoclonus 1 | 74
Neoplasm Metastasis 1 | 168
Nephrotic Syndrome 1 | 78
Neuronal loss 1 | 25
Obstruction of pelviureteric junction 1 | 8
Personality change 1 | 23
Phenotypic variability 1 | 150
RENAL ADYSPLASIA 1 | 25
Renal Cell Carcinoma 1 | 214
Renal dysplasia 1 | 28
Retinitis pigmentosa 11 1 | 59
Right atrial isomerism 1 | 29
Sarcoma of kidney 1 | 1
Sensorineural hearing loss 1 | 106
Uroureter 1 | 15
chronic kidney disease 1 | 90
non-small cell lung carcinoma 1 | 317
twin-to-twin transfusion syndrome 1 | 12
ulnar-mammary syndrome 1 | 8

Tissue

Endocrine System 21 | 18,159
Digestive Tract 19 | 17,369
Male tissues 19 | 17,142
Female tissues 18 | 17,400
Skin and soft tissues 18 | 17,230
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Blood and immune system 16 | 16,909
Liver and Pancreas 16 | 16,750
Urinary Tract 16 | 16,678
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 12 | 12,091
Enzyme 6 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

GWAS Trait

Interferon gamma-induced prote... 22 | 22
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable E3 ubiquitin-protein ligase HECTD4 HECTD4 Tbio Enzyme -1.02570 11.0 0
Phospholipid scramblase family member 5 PLSCR5 Tdark Enzyme 0.95 0.10 15
Glycine dehydrogenase (decarboxylating), mitochondrial GLDC Tbio Enzyme -1.79392 65.7 131
Serine/threonine-protein phosphatase with EF-hands 2 PPEF2 Tbio Enzyme -0.26680 1.77 58
Protein LBH LBH Tbio Non-IDG -0.40369 3.27 57
Protein Shroom3 SHROOM3 Tbio Non-IDG -1.57599 36.8 31
Pregnancy-specific beta-1-glycoprotein 2 PSG2 Tbio Non-IDG -1.22598 18.2 161
Progestin and adipoQ receptor family member 3 PAQR3 Tbio Non-IDG -1.28919 27.6 50
Rho guanine nucleotide exchange factor 28 ARHGEF28 Tbio Non-IDG -1.62506 29.7 18
Teneurin-3 TENM3 Tbio Non-IDG -2.01347 99.4 64