Development Level

Tbio 196 | 11,651
Tdark 39 | 6,593
Tchem 16 | 1,388
Tclin 16 | 612

Collection

RFA-RM-18-021 6 | 328
Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

preweaning lethality, complete... 23 | 979
abnormal behavior 14 | 298
preweaning lethality, incomple... 11 | 499
decreased grip strength 8 | 116
embryonic lethality prior to t... 7 | 278
abnormal sleep behavior 6 | 70
embryonic lethality prior to o... 6 | 239
abnormal bone structure 5 | 187
abnormal embryo size 5 | 220
abnormal heart morphology 5 | 162
enlarged heart 5 | 210
hyperactivity 5 | 148
hypoactivity 5 | 132
abnormal behavioral response t... 4 | 66
abnormal epididymis morphology 4 | 42
decreased total body fat amoun... 4 | 207
increased circulating alkaline... 4 | 122
increased mean corpuscular vol... 4 | 92
increased or absent threshold ... 4 | 101
abnormal eye morphology 3 | 68
abnormal gait 3 | 69
abnormal seminal vesicle morph... 3 | 114
decreased bone mineral content 3 | 151
decreased caudal vertebrae num... 3 | 53
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased threshold for audito... 3 | 26
decreased vertical activity 3 | 208
enlarged epididymis 3 | 31
increased bone mineral content 3 | 108
increased erythrocyte cell num... 3 | 39
increased total body fat amoun... 3 | 134
increased vertical activity 3 | 24
prenatal lethality prior to he... 3 | 87
abnormal craniofacial morpholo... 2 | 33
abnormal embryo turning 2 | 31
abnormal kidney morphology 2 | 65
abnormal spleen morphology 2 | 55
anophthalmia 2 | 33
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating fructosa... 2 | 30
decreased circulating glucose ... 2 | 126
decreased circulating total pr... 2 | 49
decreased exploration in new e... 2 | 11
decreased lean body mass 2 | 135
decreased prepulse inhibition 2 | 82
improved glucose tolerance 2 | 79
increased bone mineral density 2 | 72
increased circulating iron lev... 2 | 30
increased fasted circulating g... 2 | 76
increased heart rate 2 | 23
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
limb grasping 2 | 41
long tibia 2 | 25
shortened QT interval 2 | 4
shortened ST segment 2 | 10
small superior vagus ganglion 2 | 74
vertebral transformation 2 | 12
abnormal coat- hair morphology 1 | 19
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal motor capabilities-co... 1 | 5
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased food intake 1 | 13
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
small spleen 1 | 19
small testis 1 | 58
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 190 | 11,493
ovarian cancer 131 | 8,520
medulloblastoma, large-cell 125 | 6,241
glioblastoma 120 | 5,792
osteosarcoma 117 | 7,950
atypical teratoid / rhabdoid tumor 108 | 5,112
psoriasis 98 | 6,694
ependymoma 96 | 4,679
adult high grade glioma 80 | 3,801
lung cancer 78 | 4,740
group 3 medulloblastoma 77 | 4,104
primitive neuroectodermal tumor 67 | 3,035
astrocytic glioma 66 | 2,597
Astrocytoma, Pilocytic 64 | 3,081
Kidney cancer 64 | 2,613
oligodendroglioma 64 | 2,850
Breast cancer 58 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 56 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 50 | 2,955
subependymal giant cell astrocytoma 50 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 49 | 3,291
lung carcinoma 49 | 2,843
lung adenocarcinoma 48 | 2,716
malignant mesothelioma 46 | 3,232
non-small cell lung cancer 46 | 2,890
group 4 medulloblastoma 45 | 1,855
pancreatic cancer 44 | 2,398
pituitary cancer 44 | 1,972
Cancer 43 | 2,499
Pick disease 43 | 1,894
interstitial cystitis 38 | 2,312
invasive ductal carcinoma 38 | 2,951
Rheumatoid arthritis 30 | 1,191
ulcerative colitis 29 | 1,819
Schizophrenia 28 | 1,160
tuberculosis 28 | 2,010
ductal carcinoma in situ 27 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
adrenocortical carcinoma 25 | 1,428
colon cancer 25 | 1,478
cystic fibrosis 25 | 1,696
Intellectual disability 24 | 1,016
Liver cancer 24 | 604
breast carcinoma 24 | 1,638
diabetes mellitus 24 | 1,728
juvenile dermatomyositis 23 | 1,187
Autosomal recessive predisposition 22 | 1,442
astrocytoma 22 | 1,146
acute quadriplegic myopathy 21 | 1,158
progressive supranuclear palsy 21 | 676
aldosterone-producing adenoma 19 | 665
pediatric high grade glioma 19 | 1,064
Acquired metabolic disease 17 | 336
Endometrial cancer 17 | 311
Epilepsy 17 | 792
Multiple myeloma 17 | 1,332
dermatomyositis 17 | 966
spina bifida 17 | 1,074
Melanoma 16 | 711
primary pancreatic ductal adenocarcinoma 16 | 1,109
cutaneous lupus erythematosus 15 | 1,057
primary Sjogren syndrome 15 | 735
Crohn's disease 14 | 321
Dull intelligence 14 | 645
Low intelligence 14 | 645
Mental Retardation 14 | 645
Mental deficiency 14 | 645
Poor school performance 14 | 645
Skin cancer 14 | 469
Waldenstrons macroglobulinemia 14 | 765
Autistic Disorder 13 | 364
Bipolar Disorder 13 | 666
Parkinson's disease 12 | 392
Seizures 12 | 596
gastric cancer 12 | 459
gastric carcinoma 12 | 807
pancreatic carcinoma 12 | 562
Breast Neoplasms 11 | 445
Cognitive delay 11 | 608
Global developmental delay 11 | 608
Liver Cirrhosis, Experimental 11 | 769
Mental Depression 11 | 333
Mental and motor retardation 11 | 608
Obesity 11 | 678
Type 2 diabetes mellitus 11 | 272
active Crohn's disease 11 | 922
Amyotrophic lateral sclerosis 10 | 451
Atopic dermatitis 10 | 952
Mammary Neoplasms 10 | 425
Muscle hypotonia 10 | 571
Osteoporosis 10 | 363
acute myeloid leukemia 10 | 783
esophageal adenocarcinoma 10 | 737
interstitial lung disease 10 | 298
medulloblastoma 10 | 720
nasopharyngeal carcinoma 10 | 1,058
Cataract 9 | 297
Lens Opacities 9 | 231
Prostatic Neoplasms 9 | 495
Short stature 9 | 531

Tissue

Endocrine System 263 | 18,159
Digestive Tract 255 | 17,369
Female tissues 254 | 17,400
Male tissues 252 | 17,142
Nervous System 251 | 16,725
Skin and soft tissues 250 | 17,230
Urinary Tract 248 | 16,678
Blood and immune system 246 | 16,909
Liver and Pancreas 244 | 16,750
Respiratory system 244 | 16,393
Cardiovascular System 230 | 15,192

Target Family

Non-IDG 146 | 12,091
Enzyme 53 | 4,145
Transcription Factor 25 | 1,400
Kinase 13 | 634
Ion Channel 9 | 344
Epigenetic 8 | 242
Transporter 6 | 473
GPCR 4 | 408
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

GWAS Trait

Intelligence (multi-trait anal... 267 | 267
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box/LRR-repeat protein 17 FBXL17 Tbio Non-IDG -0.49601 3.17 90
POM121-like protein 2 POM121L2 Tdark Non-IDG 0.40 0.40 5
Polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 Tbio Enzyme -2.80894 644.1 124
Pyroglutamyl-peptidase 1 PGPEP1 Tbio Enzyme -2.39412 250.8 91
RNA binding protein fox-1 homolog 1 RBFOX1 Tbio Non-IDG -2.00815 99.2 207
Protein phosphatase 1E PPM1E Tbio Enzyme -0.97004 9.49 44
Active regulator of SIRT1 RPS19BP1 Tbio Non-IDG -1.70998 49.5 84
Secretogranin-3 SCG3 Tbio Non-IDG -1.59072 42.1 169
BAG family molecular chaperone regulator 5 BAG5 Tbio Non-IDG -1.25287 18.4 376
Arylsulfatase A ARSA Tbio Enzyme -2.50334 319.0 337