Development Level

Tbio 165 | 11,445
Tchem 38 | 1,598
Tdark 22 | 6,588
Tclin 10 | 613

Collection

GPCR: IDG Consortium (Complete... 3 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal bone structure 6 | 187
decreased vertical activity 6 | 208
preweaning lethality, incomple... 6 | 499
abnormal embryo size 5 | 220
decreased body weight 4 | 161
increased lean body mass 4 | 172
increased mean corpuscular hem... 4 | 96
abnormal behavior 3 | 298
cataract 3 | 92
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating glucose ... 3 | 126
decreased mean corpuscular vol... 3 | 79
abnormal coat-hair pigmentatio... 2 | 64
abnormal eye anterior chamber ... 2 | 9
abnormal facial morphology 2 | 17
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal limb bud morphology 2 | 17
abnormal neural tube closure 2 | 46
abnormal vertebrae morphology 2 | 18
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating insulin ... 2 | 76
decreased circulating phosphat... 2 | 27
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased large unstained cell... 2 | 11
decreased leukocyte cell numbe... 2 | 73
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
hemorrhage 2 | 23
hypoactivity 2 | 132
increased circulating choleste... 2 | 66
increased circulating serum al... 2 | 22
increased erythrocyte cell num... 2 | 39
increased grip strength 2 | 41
increased hemoglobin content 2 | 45
increased total body fat amoun... 2 | 134
pallor 2 | 34
abnormal body wall morphology 1 | 9
abnormal colon morphology 1 | 3
abnormal cornea morphology 1 | 31
abnormal duodenum morphology 1 | 4
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal head shape 1 | 10
abnormal hindbrain development 1 | 16
abnormal liver size 1 | 5
abnormal lymph node morphology 1 | 3
abnormal midbrain development 1 | 20
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
anophthalmia 1 | 33
cleft palate 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased threshold for audito... 1 | 26
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
impaired glucose tolerance 1 | 75
increased T cell number 1 | 6
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
pale liver 1 | 6
prenatal lethality prior to he... 1 | 87
unresponsive to tactile stimul... 1 | 8
vertebral fusion 1 | 23

Disease

Carcinoma 162 | 11,493
Crohn's disease 125 | 321
osteosarcoma 123 | 7,950
ovarian cancer 123 | 8,520
psoriasis 93 | 6,694
glioblastoma 92 | 5,792
lung cancer 88 | 4,740
medulloblastoma, large-cell 85 | 6,241
ulcerative colitis 84 | 1,819
Cancer 68 | 2,499
atypical teratoid / rhabdoid tumor 66 | 5,112
malignant mesothelioma 61 | 3,232
Astrocytoma, Pilocytic 60 | 3,081
ependymoma 59 | 4,679
tuberculosis 58 | 2,010
adult high grade glioma 57 | 3,801
interstitial cystitis 56 | 2,312
invasive ductal carcinoma 53 | 2,951
lung carcinoma 52 | 2,843
Rheumatoid arthritis 50 | 1,191
non-small cell lung cancer 49 | 2,890
group 3 medulloblastoma 46 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 45 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,989
Breast cancer 43 | 3,578
primitive neuroectodermal tumor 42 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,955
lung adenocarcinoma 38 | 2,716
oligodendroglioma 38 | 2,850
pituitary cancer 38 | 1,972
diabetes mellitus 37 | 1,728
Kidney cancer 35 | 2,613
pancreatic cancer 34 | 2,398
subependymal giant cell astrocytoma 33 | 2,287
astrocytic glioma 32 | 2,597
primary Sjogren syndrome 31 | 735
cystic fibrosis 30 | 1,696
Multiple Sclerosis 28 | 540
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
Pick disease 27 | 1,894
cutaneous lupus erythematosus 27 | 1,057
colon cancer 25 | 1,478
ductal carcinoma in situ 25 | 1,745
astrocytoma 24 | 1,146
Colitis, Ulcerative 23 | 59
Schizophrenia 23 | 1,160
group 4 medulloblastoma 23 | 1,855
Celiac disease 22 | 116
Multiple myeloma 22 | 1,332
non primary Sjogren syndrome sicca 22 | 891
Liver Cirrhosis, Experimental 21 | 769
juvenile dermatomyositis 21 | 1,187
pediatric high grade glioma 21 | 1,064
spina bifida 21 | 1,074
Asthma 20 | 385
Common variable immunodeficiency 19 | 101
Kidney disease 19 | 430
adrenocortical carcinoma 19 | 1,428
breast carcinoma 19 | 1,638
Autosomal recessive predisposition 18 | 1,442
acute quadriplegic myopathy 18 | 1,158
Atopic dermatitis 17 | 952
Melanoma 17 | 711
Waldenstrons macroglobulinemia 17 | 765
dermatomyositis 17 | 966
nasopharyngeal carcinoma 17 | 1,058
Alzheimer's disease 16 | 658
Breast Neoplasms 16 | 445
Crohn Disease 16 | 45
Inflammatory bowel disease 16 | 151
Skin cancer 16 | 469
esophageal adenocarcinoma 16 | 737
mucosa-associated lymphoid tissue lymphoma 16 | 484
Acquired metabolic disease 15 | 336
Arthritis, Rheumatoid 15 | 174
Hypersensitivity reaction type II disease 15 | 253
Inflammatory Bowel Diseases 15 | 35
Mammary Neoplasms 15 | 425
Obesity 15 | 678
Type 1 diabetes mellitus 15 | 109
active Crohn's disease 15 | 922
acute myeloid leukemia 15 | 783
primary pancreatic ductal adenocarcinoma 15 | 1,109
Arthritis 14 | 290
Bipolar Disorder 14 | 666
Systemic lupus erythematosus 14 | 194
active ulcerative colitis 14 | 764
gastric carcinoma 14 | 807
Liver cancer 13 | 604
Vascular disease 13 | 319
Atherosclerosis 12 | 291
Coronary artery disease 12 | 268
Hepatomegaly 12 | 285
Lupus Erythematosus, Systemic 12 | 67
Major Depressive Disorder 12 | 301
periodontitis 12 | 293
Chronic Lymphocytic Leukemia 11 | 262
Immune system cancer 11 | 140
Prostatic Neoplasms 11 | 495
gastric cancer 11 | 459

Tissue

Digestive Tract 224 | 17,369
Endocrine System 223 | 18,159
Female tissues 223 | 17,400
Skin and soft tissues 223 | 17,230
Blood and immune system 222 | 16,909
Male tissues 222 | 17,142
Urinary Tract 220 | 16,678
Liver and Pancreas 219 | 16,750
Respiratory system 218 | 16,393
Nervous System 216 | 16,725
Cardiovascular System 201 | 15,192

Target Family

Non-IDG 117 | 12,091
Enzyme 51 | 4,145
Transcription Factor 28 | 1,400
Kinase 14 | 634
GPCR 8 | 408
Epigenetic 6 | 242
Transporter 6 | 473
Nuclear Receptor 3 | 48
TF/Epigenetic 2 | 38

GWAS Trait

Inflammatory bowel disease 235 | 235
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 300 ZNF300 Tbio Transcription Factor -0.81482 8.21 85
Galactocerebrosidase GALC Tbio Enzyme -2.56924 363.2 143
COMM domain-containing protein 7 COMMD7 Tbio Non-IDG -0.95317 9.82 82
Delphilin GRID2IP Tdark Non-IDG -0.73531 6.97 47
Tubulin delta chain TUBD1 Tbio Non-IDG -1.28681 18.5 57
RING finger protein 186 RNF186 Tdark Non-IDG -0.60669 4.57 78
A-kinase anchor protein 11 AKAP11 Tbio Enzyme -1.02415 11.7 38
Aconitate hydratase, mitochondrial ACO2 Tbio Enzyme -2.21106 157.2 307
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
Fatty acid desaturase 2 FADS2 Tbio Enzyme -2.55411 349.6 135