Development Level

Tbio 88 | 11,651
Tdark 20 | 6,593
Tchem 8 | 1,388
Tclin 2 | 612

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal embryo size 6 | 220
decreased erythrocyte cell num... 4 | 62
abnormal bone structure 3 | 187
embryonic growth retardation 3 | 106
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased mean corpuscular hem... 3 | 96
preweaning lethality, incomple... 3 | 499
abnormal eye morphology 2 | 68
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased neutrophil cell numb... 2 | 42
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
edema 2 | 59
hemorrhage 2 | 23
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
prenatal lethality prior to he... 2 | 87
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal placenta morphology 1 | 5
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal stomach morphology 1 | 10
abnormal tooth morphology 1 | 24
decreased anxiety-related resp... 1 | 12
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
male infertility 1 | 123
mydriasis 1 | 6
polydactyly 1 | 7
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened RR interval 1 | 17
urinary bladder obstruction 1 | 4
vertebral transformation 1 | 12

Disease

Carcinoma 80 | 11,493
osteosarcoma 74 | 7,950
ovarian cancer 68 | 8,520
glioblastoma 51 | 5,792
medulloblastoma, large-cell 51 | 6,241
psoriasis 46 | 6,694
ependymoma 43 | 4,679
group 3 medulloblastoma 43 | 4,104
atypical teratoid / rhabdoid tumor 39 | 5,112
lung cancer 39 | 4,740
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
non-small cell lung cancer 30 | 2,890
adult high grade glioma 29 | 3,801
invasive ductal carcinoma 29 | 2,951
malignant mesothelioma 29 | 3,232
Astrocytoma, Pilocytic 28 | 3,081
Breast cancer 28 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
ulcerative colitis 28 | 1,819
Kidney cancer 26 | 2,613
lung carcinoma 26 | 2,843
oligodendroglioma 24 | 2,850
pancreatic cancer 24 | 2,398
astrocytic glioma 23 | 2,597
subependymal giant cell astrocytoma 22 | 2,287
Cancer 21 | 2,499
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
pituitary cancer 19 | 1,972
primitive neuroectodermal tumor 19 | 3,035
tuberculosis 19 | 2,010
interstitial cystitis 18 | 2,312
Autosomal recessive predisposition 17 | 1,442
ductal carcinoma in situ 17 | 1,745
Pick disease 16 | 1,894
cystic fibrosis 16 | 1,696
astrocytoma 15 | 1,146
lung adenocarcinoma 15 | 2,716
spina bifida 15 | 1,074
colon cancer 14 | 1,478
dermatomyositis 14 | 966
juvenile dermatomyositis 14 | 1,187
Rheumatoid arthritis 13 | 1,191
acute quadriplegic myopathy 13 | 1,158
group 4 medulloblastoma 13 | 1,855
Atopic dermatitis 12 | 952
breast carcinoma 12 | 1,638
mucosa-associated lymphoid tissue lymphoma 12 | 484
pediatric high grade glioma 12 | 1,064
Alzheimer's disease 11 | 658
Schizophrenia 11 | 1,160
Peripheral vascular disease 10 | 87
acute myeloid leukemia 10 | 783
cutaneous lupus erythematosus 10 | 1,057
diabetes mellitus 10 | 1,728
esophageal adenocarcinoma 10 | 737
nasopharyngeal carcinoma 10 | 1,058
primary pancreatic ductal adenocarcinoma 10 | 1,109
Liver cancer 9 | 604
Multiple myeloma 9 | 1,332
adrenocortical carcinoma 9 | 1,428
aldosterone-producing adenoma 9 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
gastric carcinoma 9 | 807
pancreatic carcinoma 9 | 562
Crohn's disease 8 | 321
Duchenne muscular dystrophy 8 | 601
Intellectual disability 8 | 1,016
Liver Cirrhosis, Experimental 8 | 769
Melanoma 8 | 711
Type 2 diabetes mellitus 8 | 272
non primary Sjogren syndrome sicca 8 | 891
Heart disease 7 | 306
Waldenstrons macroglobulinemia 7 | 765
active ulcerative colitis 7 | 764
Amyotrophic lateral sclerosis 6 | 451
Anemia 6 | 365
Skin cancer 6 | 469
Splenomegaly 6 | 190
fibroadenoma 6 | 559
gastric cancer 6 | 459
posterior fossa group A ependymoma 6 | 468
sonic hedgehog group medulloblastoma 6 | 467
Bipolar Disorder 5 | 666
Cerebrovascular disease 5 | 238
Diabetes Mellitus, Type 2 5 | 142
Dull intelligence 5 | 645
Hypertension 5 | 396
Kidney disease 5 | 430
Low intelligence 5 | 645
Lung disease 5 | 142
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Multiple Sclerosis 5 | 540
Poor school performance 5 | 645
Short stature 5 | 531
active Crohn's disease 5 | 922
head and neck cancer 5 | 271
hepatocellular carcinoma 5 | 547
tuberculosis and treatment for 3 months 5 | 179

Tissue

Female tissues 116 | 17,400
Blood and immune system 115 | 16,909
Digestive Tract 115 | 17,369
Endocrine System 115 | 18,159
Liver and Pancreas 113 | 16,750
Skin and soft tissues 112 | 17,230
Urinary Tract 112 | 16,678
Male tissues 111 | 17,142
Nervous System 110 | 16,725
Respiratory system 110 | 16,393
Cardiovascular System 105 | 15,192

Target Family

Non-IDG 68 | 12,091
Enzyme 28 | 4,145
Transcription Factor 7 | 1,400
Kinase 4 | 634
Transporter 4 | 473
Epigenetic 3 | 242
Ion Channel 2 | 344
GPCR 1 | 408
Nuclear Receptor 1 | 48

GWAS Trait

Immature fraction of reticuloc... 118 | 118
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
FH2 domain-containing protein 1 FHDC1 Tdark Non-IDG -0.13480 1.85 8
Protein NATD1 NATD1 Tdark Non-IDG 0.00000 5
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.52487 33.2 60
REST corepressor 1 RCOR1 Tbio Transcription Factor -1.96775 81.2 0
WD repeat domain phosphoinositide-interacting protein 2 WIPI2 Tbio Non-IDG -1.16004 13.0 195
Spermine oxidase SMOX Tbio Enzyme -3.09513 1199.4 58
AT-rich interactive domain-containing protein 3A ARID3A Tbio Transcription Factor -2.15937 136.5 179
Ubiquitin carboxyl-terminal hydrolase 48 USP48 Tbio Enzyme -0.56820 3.47 116
Fermitin family homolog 3 FERMT3 Tbio Non-IDG -1.84107 75.9 169