Development Level

Tbio 174 | 11,445
Tdark 46 | 6,588
Tchem 20 | 1,598
Tclin 10 | 613

Collection

RFA-RM-18-021 5 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 17 | 979
decreased bone mineral density 7 | 126
abnormal bone structure 6 | 187
preweaning lethality, incomple... 6 | 499
short tibia 6 | 97
embryonic lethality prior to t... 5 | 278
increased startle reflex 5 | 112
abnormal embryo size 4 | 220
decreased body length 4 | 101
decreased bone mineral content 4 | 151
decreased hemoglobin content 4 | 68
decreased lean body mass 4 | 135
embryonic lethality prior to o... 4 | 239
enlarged heart 4 | 210
increased total body fat amoun... 4 | 134
abnormal bone mineralization 3 | 38
abnormal heart morphology 3 | 162
decreased body weight 3 | 161
decreased erythrocyte cell num... 3 | 62
hypoactivity 3 | 132
increased circulating HDL chol... 3 | 80
increased mean corpuscular vol... 3 | 92
increased mean platelet volume 3 | 45
abnormal behavior 2 | 298
abnormal cranium morphology 2 | 36
abnormal lung morphology 2 | 26
abnormal pancreas morphology 2 | 13
cataract 2 | 92
decreased circulating alkaline... 2 | 46
decreased circulating amylase ... 2 | 28
decreased circulating bilirubi... 2 | 19
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating free fat... 2 | 31
decreased circulating insulin ... 2 | 76
decreased circulating potassiu... 2 | 20
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased mature B cell number 2 | 7
decreased startle reflex 2 | 75
hemorrhage 2 | 23
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased circulating iron lev... 2 | 30
increased circulating potassiu... 2 | 29
increased fasted circulating g... 2 | 76
increased grip strength 2 | 41
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased red blood cell distr... 1 | 41
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
impaired pupillary reflex 1 | 26
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased circulating glycerol... 1 | 9
increased circulating lipase l... 1 | 3
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased vertical activity 1 | 24
limb grasping 1 | 41
long tibia 1 | 25
microphthalmia 1 | 26
thin ventricular wall 1 | 24
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 193 | 11,493
ovarian cancer 127 | 8,520
osteosarcoma 121 | 7,950
medulloblastoma, large-cell 107 | 6,241
glioblastoma 106 | 5,792
ependymoma 95 | 4,679
psoriasis 94 | 6,694
atypical teratoid / rhabdoid tumor 89 | 5,112
lung cancer 82 | 4,740
adult high grade glioma 78 | 3,801
group 3 medulloblastoma 71 | 4,104
Kidney cancer 70 | 2,613
Astrocytoma, Pilocytic 69 | 3,081
Breast cancer 67 | 3,578
oligodendroglioma 63 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 58 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 58 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 58 | 3,291
primitive neuroectodermal tumor 56 | 3,035
lung carcinoma 53 | 2,843
malignant mesothelioma 53 | 3,232
non-small cell lung cancer 49 | 2,890
interstitial cystitis 46 | 2,312
invasive ductal carcinoma 45 | 2,951
lung adenocarcinoma 45 | 2,716
astrocytic glioma 44 | 2,597
pancreatic cancer 44 | 2,398
pituitary cancer 44 | 1,972
Cancer 42 | 2,499
cystic fibrosis 39 | 1,696
Pick disease 38 | 1,894
subependymal giant cell astrocytoma 38 | 2,287
tuberculosis 33 | 2,010
Liver cancer 31 | 604
ulcerative colitis 30 | 1,819
Schizophrenia 28 | 1,160
group 4 medulloblastoma 28 | 1,855
Autosomal recessive predisposition 27 | 1,442
breast carcinoma 27 | 1,638
Melanoma 26 | 711
Skin cancer 25 | 469
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
Intellectual disability 23 | 1,016
colon cancer 23 | 1,478
Rheumatoid arthritis 22 | 1,191
astrocytoma 22 | 1,146
juvenile dermatomyositis 22 | 1,187
ductal carcinoma in situ 21 | 1,745
adrenocortical carcinoma 20 | 1,428
Atopic dermatitis 18 | 952
pediatric high grade glioma 18 | 1,064
Bipolar Disorder 17 | 666
dermatomyositis 17 | 966
nasopharyngeal carcinoma 17 | 1,058
Autistic Disorder 16 | 364
Dull intelligence 16 | 645
Liver Cirrhosis, Experimental 16 | 769
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Poor school performance 16 | 645
acute quadriplegic myopathy 16 | 1,158
cutaneous lupus erythematosus 16 | 1,057
primary Sjogren syndrome 16 | 735
Epilepsy 14 | 792
diabetes mellitus 14 | 1,728
primary pancreatic ductal adenocarcinoma 14 | 1,109
Endometrial cancer 13 | 311
Waldenstrons macroglobulinemia 13 | 765
gastric carcinoma 13 | 807
active Crohn's disease 12 | 922
active ulcerative colitis 12 | 764
chronic rhinosinusitis 12 | 512
medulloblastoma 12 | 720
non primary Sjogren syndrome sicca 12 | 891
progressive supranuclear palsy 12 | 676
Acquired metabolic disease 11 | 336
Attention deficit hyperactivity disorder 11 | 278
Breast Neoplasms 11 | 445
Multiple myeloma 11 | 1,332
Muscle hypotonia 11 | 571
sonic hedgehog group medulloblastoma 11 | 467
spina bifida 11 | 1,074
Acquired scoliosis 10 | 281
Crohn's disease 10 | 321
Curvature of spine 10 | 282
Mammary Neoplasms 10 | 425
Obesity 10 | 678
Parkinson's disease 10 | 392
Seizures 10 | 596
Short stature 10 | 531
Type 2 diabetes mellitus 10 | 272
acute myeloid leukemia 10 | 783
fibroadenoma 10 | 559
pancreatic carcinoma 10 | 562
urothelial carcinoma 10 | 318
Asthma 9 | 385
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608

Tissue

Endocrine System 241 | 18,159
Female tissues 232 | 17,400
Digestive Tract 231 | 17,369
Nervous System 231 | 16,725
Male tissues 230 | 17,142
Skin and soft tissues 225 | 17,230
Liver and Pancreas 222 | 16,750
Urinary Tract 220 | 16,678
Blood and immune system 216 | 16,909
Respiratory system 213 | 16,393
Cardiovascular System 196 | 15,192

Target Family

Non-IDG 149 | 12,091
Enzyme 41 | 4,145
Transcription Factor 19 | 1,400
GPCR 11 | 408
Transporter 9 | 473
Epigenetic 7 | 242
Kinase 7 | 634
Ion Channel 6 | 344
Nuclear Receptor 1 | 48

GWAS Trait

IgG glycosylation 250 | 250
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86
Glutamate-rich protein 1 ERICH1 Tdark Non-IDG 0.35 0.38 18
Proline-rich transmembrane protein 1 PRRT1 Tbio Non-IDG -1.33375 18.2 68
Collagen alpha-1(XIX) chain COL19A1 Tbio Non-IDG -0.75672 6.18 137
Metabotropic glutamate receptor 3 GRM3 Tchem GPCR -2.30964 186.9 274
Roundabout homolog 2 ROBO2 Tbio Non-IDG -1.89275 74.1 161
RNA-binding protein Raly RALY Tbio Non-IDG -1.12263 14.4 176
Zinc finger protein 804B ZNF804B Tdark Non-IDG -0.10075 1.01 14
Anterior gradient protein 2 homolog AGR2 Tbio Non-IDG -2.07496 136.6 594