Development Level

Tbio 12 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

abnormal heart morphology 1 | 162
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
embryonic lethality prior to o... 1 | 239
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 14 | 11,493
osteosarcoma 9 | 7,950
Cancer 8 | 2,499
ovarian cancer 8 | 8,520
Autosomal recessive predisposition 7 | 1,442
Dull intelligence 7 | 645
Intellectual disability 7 | 1,016
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
medulloblastoma, large-cell 6 | 6,241
Atherosclerosis 5 | 291
Epilepsy 5 | 792
Homocystinuria 5 | 21
Seizures 5 | 596
glioblastoma 5 | 5,792
psoriasis 5 | 6,694
Anemia 4 | 365
Breast cancer 4 | 3,578
Dementia 4 | 175
Down syndrome 4 | 499
Hyperhomocysteinemia 4 | 37
Kidney cancer 4 | 2,613
Kidney disease 4 | 430
Liver cancer 4 | 604
Melanoma 4 | 711
Vitamin B12 deficiency 4 | 20
atypical teratoid / rhabdoid tumor 4 | 5,112
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
spina bifida 4 | 1,074
Bipolar Disorder 3 | 666
Comatose 3 | 56
Depressive disorder 3 | 409
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Dystonia 3 | 164
Failure to gain weight 3 | 365
Hyperglycemia 3 | 137
Hypertension 3 | 396
Lethargy 3 | 77
Leukopenia 3 | 72
Malnutrition 3 | 11
Muscle hypotonia 3 | 571
Neurodegenerative disease 3 | 414
Pediatric failure to thrive 3 | 365
Schizophrenia 3 | 1,160
Thrombocytopenia 3 | 197
Vomiting 3 | 116
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
nephrosclerosis 3 | 333
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
progressive supranuclear palsy 3 | 676
Acquired scoliosis 2 | 281
Alcoholic Intoxication 2 | 34
Alzheimer's disease 2 | 658
Bladder Neoplasm 2 | 112
Brain Ischemia 2 | 110
Cardiovascular Diseases 2 | 59
Cerebrovascular accident 2 | 63
Cerebrovascular disease 2 | 238
Colonic Neoplasms 2 | 142
Congenital Heart Defects 2 | 58
Congenital clubfoot 2 | 109
Congenital heart disease 2 | 93
Curvature of spine 2 | 282
Disease of metabolism 2 | 18
Frontotemporal dementia 2 | 51
Gastrointestinal Diseases 2 | 12
Gout 2 | 106
Hematological Disease 2 | 18
Hepatomegaly 2 | 285
Hyperammonemia 2 | 30
Infantile onset 2 | 238
Infertility, Male 2 | 46
Leukoencephalopathies 2 | 29
Lipid metabolism disorder 2 | 114
Liver Cirrhosis, Experimental 2 | 769
Lung Neoplasms 2 | 232
Male infertility 2 | 206
Mental Depression 2 | 333
Methylmalonic acidemia 2 | 37
Myopia 2 | 176
Paresthesia 2 | 32
Peripheral vascular disease 2 | 87
Pulmonary embolism 2 | 55
Tinea corporis 2 | 25
Urinary Bladder Neoplasms 2 | 114
Vascular disease 2 | 319
cystic fibrosis 2 | 1,696
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Endocrine System 18 | 18,159
Liver and Pancreas 17 | 16,750
Urinary Tract 17 | 16,678
Blood and immune system 16 | 16,909
Female tissues 16 | 17,400
Male tissues 16 | 17,142
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Nervous System 14 | 16,725

Target Family

Enzyme 8 | 4,145
Non-IDG 8 | 12,091
Transcription Factor 1 | 1,400
Transporter 1 | 473

GWAS Trait

Homocysteine levels 18 | 18
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Methionine synthase MTR Tbio Enzyme -2.56900 300.2 87
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161
Cystathionine beta-synthase-like protein CBS Tbio Non-IDG -3.25635 3246.1 0
Methylmalonyl-CoA mutase, mitochondrial MUT Tbio Enzyme -2.51690 305.3 99
Uncharacterized protein C1orf167 C1orf167 Tdark Non-IDG 0.90 0.05 3
Peroxiredoxin-1 PRDX1 Tbio Non-IDG -2.57725 399.0 466
tRNA (cytosine(38)-C(5))-methyltransferase TRDMT1 Tbio Enzyme -1.99628 94.9 337
Carbamoyl-phosphate synthase [ammonia], mitochondrial CPS1 Tclin Enzyme -2.28267 188.9 238
Cystathionine beta-synthase CBS Tchem Enzyme -3.25635 3246.1 391