Development Level

Tbio 65 | 11,445
Tdark 14 | 6,588
Tchem 5 | 1,598
Tclin 5 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 8 | 979
decreased lymphocyte cell numb... 3 | 83
preweaning lethality, incomple... 3 | 499
abnormal cranium morphology 2 | 36
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased body weight 2 | 25
increased hemoglobin content 2 | 45
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart shape 1 | 5
abnormal incisor morphology 1 | 4
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
edema 1 | 59
enlarged epididymis 1 | 31
hemorrhage 1 | 23
increased CD8-positive, alpha-... 1 | 1
increased T cell number 1 | 6
increased blood urea nitrogen ... 1 | 48
increased circulating glycerol... 1 | 9
increased erythrocyte cell num... 1 | 39
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
urinary bladder obstruction 1 | 4

Disease

Carcinoma 66 | 11,493
ovarian cancer 52 | 8,520
osteosarcoma 50 | 7,950
medulloblastoma, large-cell 44 | 6,241
atypical teratoid / rhabdoid tumor 39 | 5,112
Acquired metabolic disease 37 | 336
glioblastoma 37 | 5,792
psoriasis 37 | 6,694
ependymoma 34 | 4,679
group 3 medulloblastoma 33 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
lung cancer 31 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
malignant mesothelioma 26 | 3,232
Breast cancer 25 | 3,578
adult high grade glioma 24 | 3,801
pancreatic cancer 24 | 2,398
primitive neuroectodermal tumor 24 | 3,035
Astrocytoma, Pilocytic 22 | 3,081
lung adenocarcinoma 20 | 2,716
lung carcinoma 19 | 2,843
non-small cell lung cancer 19 | 2,890
invasive ductal carcinoma 18 | 2,951
Cancer 17 | 2,499
interstitial cystitis 17 | 2,312
ductal carcinoma in situ 16 | 1,745
oligodendroglioma 16 | 2,850
ulcerative colitis 16 | 1,819
astrocytic glioma 15 | 2,597
cystic fibrosis 15 | 1,696
Kidney cancer 14 | 2,613
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Pick disease 13 | 1,894
adrenocortical carcinoma 13 | 1,428
subependymal giant cell astrocytoma 13 | 2,287
Autosomal recessive predisposition 12 | 1,442
group 4 medulloblastoma 11 | 1,855
pituitary cancer 11 | 1,972
tuberculosis 11 | 2,010
Rheumatoid arthritis 10 | 1,191
breast carcinoma 10 | 1,638
esophageal adenocarcinoma 10 | 737
astrocytoma 9 | 1,146
diabetes mellitus 9 | 1,728
primary pancreatic ductal adenocarcinoma 9 | 1,109
progressive supranuclear palsy 9 | 676
spina bifida 9 | 1,074
Multiple myeloma 8 | 1,332
Short stature 8 | 531
colon cancer 8 | 1,478
Endometriosis 7 | 540
Melanoma 7 | 711
dermatomyositis 7 | 966
juvenile dermatomyositis 7 | 1,187
nasopharyngeal carcinoma 7 | 1,058
pancreatic carcinoma 7 | 562
Atopic dermatitis 6 | 952
Brachydactyly 6 | 156
Cognitive delay 6 | 608
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Polycystic ovary syndrome 6 | 360
Type 2 diabetes mellitus 6 | 272
active Crohn's disease 6 | 922
active ulcerative colitis 6 | 764
acute quadriplegic myopathy 6 | 1,158
gastric cancer 6 | 459
pediatric high grade glioma 6 | 1,064
Acquired scoliosis 5 | 281
Adenoma 5 | 167
Chronic obstructive pulmonary disease 5 | 184
Curvature of spine 5 | 282
Diabetes Mellitus, Type 2 5 | 142
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Obesity 5 | 678
Osteoarthritis 5 | 184
Osteoporosis 5 | 363
Poor school performance 5 | 645
Schizophrenia 5 | 1,160
acute myeloid leukemia 5 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
gastric carcinoma 5 | 807
non-small cell lung carcinoma 5 | 317
sonic hedgehog group medulloblastoma 5 | 467
Alzheimer's disease 4 | 658
Arthritis, Rheumatoid 4 | 174
Cleft Palate 4 | 271
Crohn's disease 4 | 321
Micromelia 4 | 58
Multiple Sclerosis 4 | 540
Prostatic Neoplasms 4 | 495
aldosterone-producing adenoma 4 | 665
hepatocellular carcinoma 4 | 547
primary Sjogren syndrome 4 | 735

Tissue

Digestive Tract 87 | 17,369
Endocrine System 87 | 18,159
Female tissues 87 | 17,400
Liver and Pancreas 87 | 16,750
Male tissues 87 | 17,142
Nervous System 87 | 16,725
Skin and soft tissues 87 | 17,230
Urinary Tract 87 | 16,678
Respiratory system 86 | 16,393
Blood and immune system 85 | 16,909
Cardiovascular System 81 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 15 | 4,145
Transcription Factor 11 | 1,400
Epigenetic 3 | 242
Kinase 3 | 634
Transporter 3 | 473
GPCR 1 | 408
Nuclear Receptor 1 | 48

GWAS Trait

Hip circumference adjusted for... 89 | 89
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Leucine-rich repeat-containing protein 1 LRRC1 Tbio Non-IDG -1.15510 13.7 73
Insulin-like growth factor 2 mRNA-binding protein 2 IGF2BP2 Tbio Non-IDG -1.77792 57.3 400
ATP-dependent RNA helicase DDX42 DDX42 Tbio Enzyme -1.10894 13.3 60
Putative helicase MOV-10 MOV10 Tbio Enzyme -1.55297 38.5 121
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Mitochondrial import inner membrane translocase subunit TIM16 PAM16 Tbio Enzyme -2.36396 227.6 45
F-box/WD repeat-containing protein 2 FBXW2 Tbio Non-IDG -2.09381 115.1 104
Death domain-containing protein CRADD CRADD Tbio Non-IDG -1.34614 23.0 400