Development Level

Tbio 42 | 11,445
Tchem 6 | 1,598
Tdark 4 | 6,588
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 5 | 499
hypoactivity 3 | 132
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased lactate dehydrogenas... 2 | 16
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
enlarged heart 2 | 210
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal kidney morphology 1 | 65
abnormal lymph node morphology 1 | 3
abnormal male genitalia morpho... 1 | 3
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
edema 1 | 59
enlarged seminal vesicle 1 | 10
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
oligodactyly 1 | 1
polydactyly 1 | 7
small kidney 1 | 16
thrombocytopenia 1 | 56
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 39 | 11,493
Acquired metabolic disease 32 | 336
ovarian cancer 28 | 8,520
osteosarcoma 27 | 7,950
medulloblastoma, large-cell 26 | 6,241
psoriasis 22 | 6,694
Obesity 19 | 678
glioblastoma 19 | 5,792
Breast cancer 18 | 3,578
atypical teratoid / rhabdoid tumor 18 | 5,112
lung cancer 17 | 4,740
ependymoma 16 | 4,679
Kidney cancer 15 | 2,613
adult high grade glioma 15 | 3,801
group 3 medulloblastoma 12 | 4,104
malignant mesothelioma 12 | 3,232
Astrocytoma, Pilocytic 11 | 3,081
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
primitive neuroectodermal tumor 11 | 3,035
astrocytic glioma 10 | 2,597
lung adenocarcinoma 10 | 2,716
oligodendroglioma 10 | 2,850
Cancer 9 | 2,499
subependymal giant cell astrocytoma 9 | 2,287
astrocytoma 8 | 1,146
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
invasive ductal carcinoma 8 | 2,951
non-small cell lung cancer 8 | 2,890
pancreatic cancer 8 | 2,398
pituitary cancer 8 | 1,972
Autosomal recessive predisposition 7 | 1,442
colon cancer 7 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
ulcerative colitis 7 | 1,819
Body Weight 6 | 14
Melanoma 6 | 711
Pick disease 6 | 1,894
Short stature 6 | 531
Type 2 diabetes mellitus 6 | 272
adrenocortical carcinoma 6 | 1,428
ductal carcinoma in situ 6 | 1,745
lung carcinoma 6 | 2,843
Autistic Disorder 5 | 364
Epilepsy 5 | 792
Intellectual disability 5 | 1,016
Polycystic ovary syndrome 5 | 360
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
gastric carcinoma 5 | 807
Alcoholic Intoxication, Chronic 4 | 289
Amyotrophic lateral sclerosis 4 | 451
Bipolar Disorder 4 | 666
Blepharoptosis 4 | 231
Cognitive delay 4 | 608
Diabetes Mellitus, Type 2 4 | 142
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Liver cancer 4 | 604
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Osteoporosis 4 | 363
Poor school performance 4 | 645
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
Adenoma 3 | 167
Alzheimer's disease 3 | 658
Asthma 3 | 385
Atopic dermatitis 3 | 952
Attention deficit hyperactivity disorder 3 | 278
Crohn's disease 3 | 321
Depressive disorder 3 | 409
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Endometriosis 3 | 540
Language Delay 3 | 112
Mental Depression 3 | 333
Multiple Sclerosis 3 | 540
Prostatic Neoplasms 3 | 495
Psychotic Disorders 3 | 151
Seizures 3 | 596
Speech Delay 3 | 112
Speech impairment 3 | 112
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
cutaneous lupus erythematosus 3 | 1,057
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Digestive Tract 53 | 17,369
Endocrine System 53 | 18,159
Female tissues 53 | 17,400
Male tissues 53 | 17,142
Nervous System 53 | 16,725
Respiratory system 52 | 16,393
Skin and soft tissues 52 | 17,230
Urinary Tract 52 | 16,678
Blood and immune system 51 | 16,909
Liver and Pancreas 51 | 16,750
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 25 | 12,091
Enzyme 14 | 4,145
Transcription Factor 8 | 1,400
GPCR 3 | 408
Kinase 2 | 634
Transporter 2 | 473
Epigenetic 1 | 242

GWAS Trait

Hip circumference 55 | 55
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA annealing helicase and endonuclease ZRANB3 ZRANB3 Tbio Enzyme -2.18014 154.3 36
Neurexin-3 NRXN3 Tbio Non-IDG -1.34072 34.8 172
Plexin-D1 PLXND1 Tbio Non-IDG -1.64721 46.3 171
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Anaphase-promoting complex subunit 10 ANAPC10 Tbio Enzyme -1.23751 18.1 156
UHRF1-binding protein 1 UHRF1BP1 Tbio Non-IDG -1.30331 22.0 34
Neurexin-3-beta NRXN3 Tbio Non-IDG -1.34072 34.8 172
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.88264 723.0 847