Development Level

Tbio 109 | 11,651
Tdark 21 | 6,593
Tchem 16 | 1,388
Tclin 7 | 612

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal embryo size 6 | 220
decreased erythrocyte cell num... 5 | 62
decreased total body fat amoun... 5 | 207
preweaning lethality, incomple... 5 | 499
increased circulating alkaline... 4 | 122
increased mean corpuscular hem... 4 | 96
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
abnormal sleep behavior 3 | 70
decreased circulating serum al... 3 | 82
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
hypoactivity 3 | 132
increased lean body mass 3 | 172
male infertility 3 | 123
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal retina morphology 2 | 71
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased neutrophil cell numb... 2 | 42
decreased vertical activity 2 | 208
edema 2 | 59
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
increased circulating choleste... 2 | 66
increased circulating free fat... 2 | 20
increased circulating iron lev... 2 | 30
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal outer ear morphology 1 | 3
abnormal placenta size 1 | 20
abnormal retinal inner nuclear... 1 | 8
abnormal snout morphology 1 | 23
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating lactate ... 1 | 3
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
hemorrhage 1 | 23
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 24
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened RR interval 1 | 17
small testis 1 | 58
small thymus 1 | 16
tremors 1 | 39
vertebral transformation 1 | 12

Disease

Carcinoma 110 | 11,493
osteosarcoma 90 | 7,950
ovarian cancer 84 | 8,520
glioblastoma 67 | 5,792
medulloblastoma, large-cell 64 | 6,241
atypical teratoid / rhabdoid tumor 57 | 5,112
ependymoma 57 | 4,679
lung cancer 55 | 4,740
psoriasis 52 | 6,694
group 3 medulloblastoma 45 | 4,104
adult high grade glioma 42 | 3,801
invasive ductal carcinoma 41 | 2,951
Astrocytoma, Pilocytic 39 | 3,081
Breast cancer 38 | 3,578
Cancer 36 | 2,499
malignant mesothelioma 34 | 3,232
ulcerative colitis 34 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
oligodendroglioma 33 | 2,850
Kidney cancer 32 | 2,613
astrocytic glioma 32 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
pancreatic cancer 32 | 2,398
non-small cell lung cancer 30 | 2,890
lung carcinoma 29 | 2,843
primitive neuroectodermal tumor 29 | 3,035
tuberculosis 26 | 2,010
subependymal giant cell astrocytoma 25 | 2,287
Pick disease 24 | 1,894
ductal carcinoma in situ 24 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
astrocytoma 21 | 1,146
cystic fibrosis 21 | 1,696
lung adenocarcinoma 20 | 2,716
breast carcinoma 19 | 1,638
colon cancer 19 | 1,478
interstitial cystitis 19 | 2,312
Autosomal recessive predisposition 18 | 1,442
Schizophrenia 18 | 1,160
dermatomyositis 18 | 966
pituitary cancer 17 | 1,972
Multiple myeloma 16 | 1,332
diabetes mellitus 16 | 1,728
group 4 medulloblastoma 16 | 1,855
Rheumatoid arthritis 15 | 1,191
mucosa-associated lymphoid tissue lymphoma 15 | 484
acute myeloid leukemia 14 | 783
adrenocortical carcinoma 14 | 1,428
spina bifida 14 | 1,074
Anemia 13 | 365
acute quadriplegic myopathy 13 | 1,158
esophageal adenocarcinoma 13 | 737
primary pancreatic ductal adenocarcinoma 13 | 1,109
Peripheral vascular disease 12 | 87
Type 2 diabetes mellitus 12 | 272
gastric carcinoma 12 | 807
juvenile dermatomyositis 12 | 1,187
Alzheimer's disease 11 | 658
Obesity 11 | 678
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
pancreatic carcinoma 11 | 562
Bipolar Disorder 10 | 666
Crohn's disease 10 | 321
Duchenne muscular dystrophy 10 | 601
Kidney disease 10 | 430
Vascular disease 10 | 319
aldosterone-producing adenoma 10 | 665
pediatric high grade glioma 10 | 1,064
Atopic dermatitis 9 | 952
Hemolytic anemia 9 | 77
Liver Cirrhosis, Experimental 9 | 769
Melanoma 9 | 711
Short stature 9 | 531
Waldenstrons macroglobulinemia 9 | 765
active Crohn's disease 9 | 922
non primary Sjogren syndrome sicca 9 | 891
Intellectual disability 8 | 1,016
Neurodegenerative disease 8 | 414
cutaneous lupus erythematosus 8 | 1,057
fibroadenoma 8 | 559
nasopharyngeal carcinoma 8 | 1,058
primary Sjogren syndrome 8 | 735
Amyotrophic lateral sclerosis 7 | 451
Chronic Lymphocytic Leukemia 7 | 262
Diabetes Mellitus, Experimental 7 | 108
Muscle hypotonia 7 | 571
Skin cancer 7 | 469
gastric cancer 7 | 459
Atherosclerosis 6 | 291
Cerebrovascular disease 6 | 238
Down syndrome 6 | 499
Dull intelligence 6 | 645
Epilepsy 6 | 792
Essential Hypertension 6 | 94
Hypertension 6 | 396
Mental Depression 6 | 333
Poor school performance 6 | 645
chronic rhinosinusitis 6 | 512
hepatocellular carcinoma 6 | 547

Tissue

Female tissues 152 | 17,400
Blood and immune system 151 | 16,909
Endocrine System 151 | 18,159
Digestive Tract 150 | 17,369
Skin and soft tissues 147 | 17,230
Urinary Tract 147 | 16,678
Liver and Pancreas 146 | 16,750
Male tissues 146 | 17,142
Nervous System 143 | 16,725
Respiratory system 143 | 16,393
Cardiovascular System 136 | 15,192

Target Family

Non-IDG 88 | 12,091
Enzyme 39 | 4,145
Kinase 8 | 634
Transcription Factor 6 | 1,400
Ion Channel 4 | 344
GPCR 3 | 408
Epigenetic 2 | 242
Transporter 2 | 473
Nuclear Receptor 1 | 48

GWAS Trait

High light scatter reticulocyt... 153 | 153
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83
Ubiquitin carboxyl-terminal hydrolase 3 USP3 Tbio Enzyme -1.16770 14.5 246
Vacuolar protein sorting-associated protein 37D VPS37D Tdark Non-IDG 0.51 0.16 8
Spermine oxidase SMOX Tbio Enzyme -3.09513 1199.4 58
Ubiquitin carboxyl-terminal hydrolase 48 USP48 Tbio Enzyme -0.56820 3.47 116
HBS1-like protein HBS1L Tbio Non-IDG -2.55785 357.2 263
Fermitin family homolog 3 FERMT3 Tbio Non-IDG -1.84107 75.9 169
AP-2 complex subunit beta AP2B1 Tbio Non-IDG -1.59767 34.8 212
Unconventional myosin-Id MYO1D Tbio Non-IDG -1.39704 23.1 63
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.77874 581.3 185