Development Level

Tbio 113 | 11,651
Tdark 21 | 6,593
Tchem 17 | 1,388
Tclin 7 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 11 | 979
decreased total body fat amoun... 6 | 207
abnormal embryo size 5 | 220
increased circulating alkaline... 5 | 122
preweaning lethality, incomple... 5 | 499
decreased erythrocyte cell num... 4 | 62
decreased vertical activity 4 | 208
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
abnormal eye morphology 3 | 68
abnormal sleep behavior 3 | 70
decreased circulating serum al... 3 | 82
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
hypoactivity 3 | 132
increased bone mineral content 3 | 108
increased circulating choleste... 3 | 66
increased lean body mass 3 | 172
increased mean corpuscular hem... 3 | 96
male infertility 3 | 123
abnormal cornea morphology 2 | 31
abnormal cranium morphology 2 | 36
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
corneal opacity 2 | 32
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased grip strength 2 | 116
decreased startle reflex 2 | 75
decreased total retina thickne... 2 | 17
edema 2 | 59
embryonic lethality prior to o... 2 | 239
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating free fat... 2 | 20
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
mydriasis 2 | 6
vertebral transformation 2 | 12
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal placenta size 1 | 20
abnormal retinal inner nuclear... 1 | 8
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal stomach morphology 1 | 10
abnormal thymus morphology 1 | 7
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
absent seminal vesicle 1 | 4
absent testes 1 | 6
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating lactate ... 1 | 3
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
enlarged spleen 1 | 41
hemorrhage 1 | 23
hyperactivity 1 | 148
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart left ventricle... 1 | 4
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
shortened RR interval 1 | 17
small thymus 1 | 16
tremors 1 | 39

Disease

Carcinoma 109 | 11,493
osteosarcoma 90 | 7,950
ovarian cancer 87 | 8,520
glioblastoma 72 | 5,792
medulloblastoma, large-cell 68 | 6,241
atypical teratoid / rhabdoid tumor 58 | 5,112
ependymoma 58 | 4,679
lung cancer 58 | 4,740
psoriasis 55 | 6,694
group 3 medulloblastoma 51 | 4,104
Breast cancer 43 | 3,578
adult high grade glioma 43 | 3,801
invasive ductal carcinoma 43 | 2,951
malignant mesothelioma 39 | 3,232
Astrocytoma, Pilocytic 37 | 3,081
oligodendroglioma 37 | 2,850
Cancer 35 | 2,499
Kidney cancer 35 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
primitive neuroectodermal tumor 33 | 3,035
astrocytic glioma 32 | 2,597
non-small cell lung cancer 32 | 2,890
pancreatic cancer 31 | 2,398
ulcerative colitis 31 | 1,819
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
lung carcinoma 29 | 2,843
subependymal giant cell astrocytoma 29 | 2,287
tuberculosis 28 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
Pick disease 25 | 1,894
ductal carcinoma in situ 25 | 1,745
lung adenocarcinoma 25 | 2,716
breast carcinoma 23 | 1,638
cystic fibrosis 21 | 1,696
group 4 medulloblastoma 21 | 1,855
astrocytoma 20 | 1,146
Schizophrenia 19 | 1,160
interstitial cystitis 18 | 2,312
Autosomal recessive predisposition 17 | 1,442
Rheumatoid arthritis 17 | 1,191
colon cancer 17 | 1,478
diabetes mellitus 17 | 1,728
dermatomyositis 16 | 966
pituitary cancer 16 | 1,972
spina bifida 16 | 1,074
Multiple myeloma 15 | 1,332
juvenile dermatomyositis 15 | 1,187
acute myeloid leukemia 14 | 783
adrenocortical carcinoma 14 | 1,428
mucosa-associated lymphoid tissue lymphoma 14 | 484
esophageal adenocarcinoma 13 | 737
primary pancreatic ductal adenocarcinoma 13 | 1,109
Atopic dermatitis 12 | 952
Peripheral vascular disease 12 | 87
acute quadriplegic myopathy 12 | 1,158
pancreatic carcinoma 12 | 562
Alzheimer's disease 11 | 658
Bipolar Disorder 11 | 666
Duchenne muscular dystrophy 11 | 601
Type 2 diabetes mellitus 11 | 272
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
pediatric high grade glioma 11 | 1,064
Anemia 10 | 365
Crohn's disease 10 | 321
Intellectual disability 10 | 1,016
Liver Cirrhosis, Experimental 10 | 769
Muscle hypotonia 10 | 571
active Crohn's disease 10 | 922
cutaneous lupus erythematosus 10 | 1,057
fibroadenoma 10 | 559
gastric carcinoma 10 | 807
Hemolytic anemia 9 | 77
Short stature 9 | 531
gastric cancer 9 | 459
Amyotrophic lateral sclerosis 8 | 451
Diabetes Mellitus, Experimental 8 | 108
Kidney disease 8 | 430
Obesity 8 | 678
Splenomegaly 8 | 190
aldosterone-producing adenoma 8 | 665
nasopharyngeal carcinoma 8 | 1,058
non primary Sjogren syndrome sicca 8 | 891
Asthma 7 | 385
Dull intelligence 7 | 645
Essential Hypertension 7 | 94
Liver cancer 7 | 604
Low intelligence 7 | 645
Melanoma 7 | 711
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Neurodegenerative disease 7 | 414
Osteoporosis 7 | 363
Poor school performance 7 | 645
Vascular disease 7 | 319
primary Sjogren syndrome 7 | 735
Attention deficit hyperactivity disorder 6 | 278
Chronic Lymphocytic Leukemia 6 | 262
head and neck cancer 6 | 271
hepatocellular carcinoma 6 | 547

Tissue

Endocrine System 157 | 18,159
Female tissues 157 | 17,400
Blood and immune system 155 | 16,909
Digestive Tract 155 | 17,369
Male tissues 153 | 17,142
Skin and soft tissues 153 | 17,230
Urinary Tract 152 | 16,678
Liver and Pancreas 151 | 16,750
Respiratory system 150 | 16,393
Nervous System 149 | 16,725
Cardiovascular System 142 | 15,192

Target Family

Non-IDG 92 | 12,091
Enzyme 39 | 4,145
Transcription Factor 9 | 1,400
Kinase 7 | 634
Ion Channel 4 | 344
Epigenetic 3 | 242
Transporter 2 | 473
GPCR 1 | 408
Nuclear Receptor 1 | 48

GWAS Trait

High light scatter reticulocyt... 158 | 158
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83
Ubiquitin carboxyl-terminal hydrolase 3 USP3 Tbio Enzyme -1.16770 14.5 246
ADP-ribosylation factor-like protein 15 ARL15 Tbio Enzyme -1.19117 15.8 82
Vacuolar protein sorting-associated protein 37D VPS37D Tdark Non-IDG 0.51 0.16 8
Spermine oxidase SMOX Tbio Enzyme -3.09513 1199.4 58
Ubiquitin carboxyl-terminal hydrolase 48 USP48 Tbio Enzyme -0.56820 3.47 116
HBS1-like protein HBS1L Tbio Non-IDG -2.55785 357.2 263
Fermitin family homolog 3 FERMT3 Tbio Non-IDG -1.84107 75.9 169
Kelch-like protein 11 KLHL11 Tdark Non-IDG -0.17587 0.58 71
AP-2 complex subunit beta AP2B1 Tbio Non-IDG -1.59767 34.8 212