Development Level

Tbio 83 | 11,445
Tchem 12 | 1,598
Tdark 11 | 6,588
Tclin 7 | 613

Collection

Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased body weight 3 | 161
decreased circulating glucose ... 3 | 126
decreased circulating iron lev... 3 | 32
decreased erythrocyte cell num... 3 | 62
decreased prepulse inhibition 3 | 82
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal locomotor activation 2 | 16
abnormal startle reflex 2 | 15
decreased circulating serum al... 2 | 82
decreased heart left ventricle... 2 | 28
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
increased circulating amylase ... 2 | 25
increased circulating glucose ... 2 | 24
increased circulating iron lev... 2 | 30
increased lean body mass 2 | 172
increased startle reflex 2 | 112
limb grasping 2 | 41
preweaning lethality, incomple... 2 | 499
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
thin ventricular wall 2 | 24
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal limb morphology 1 | 13
abnormal outer ear morphology 1 | 3
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal vertebrae morphology 1 | 18
cyanosis 1 | 7
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating lipase l... 1 | 3
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
edema 1 | 59
hemorrhage 1 | 23
increased B cell number 1 | 9
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased total retina thickne... 1 | 4
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97

Disease

Carcinoma 88 | 11,493
ovarian cancer 67 | 8,520
osteosarcoma 60 | 7,950
medulloblastoma, large-cell 53 | 6,241
psoriasis 42 | 6,694
atypical teratoid / rhabdoid tumor 41 | 5,112
lung cancer 41 | 4,740
glioblastoma 38 | 5,792
group 3 medulloblastoma 37 | 4,104
ependymoma 33 | 4,679
adult high grade glioma 29 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
malignant mesothelioma 28 | 3,232
Cancer 27 | 2,499
Breast cancer 25 | 3,578
lung adenocarcinoma 24 | 2,716
Kidney cancer 23 | 2,613
invasive ductal carcinoma 23 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
primitive neuroectodermal tumor 22 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
pancreatic cancer 21 | 2,398
astrocytic glioma 20 | 2,597
non-small cell lung cancer 20 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
ductal carcinoma in situ 18 | 1,745
cystic fibrosis 17 | 1,696
breast carcinoma 16 | 1,638
lung carcinoma 16 | 2,843
oligodendroglioma 16 | 2,850
tuberculosis 16 | 2,010
Astrocytoma, Pilocytic 15 | 3,081
Autosomal recessive predisposition 15 | 1,442
pituitary cancer 15 | 1,972
subependymal giant cell astrocytoma 15 | 2,287
Rheumatoid arthritis 14 | 1,191
diabetes mellitus 14 | 1,728
spina bifida 13 | 1,074
ulcerative colitis 13 | 1,819
Melanoma 12 | 711
Peripheral vascular disease 12 | 87
Schizophrenia 12 | 1,160
Kidney disease 11 | 430
Pick disease 11 | 1,894
Type 2 diabetes mellitus 11 | 272
colon cancer 11 | 1,478
Anemia 10 | 365
Atopic dermatitis 10 | 952
Gout 10 | 106
astrocytoma 10 | 1,146
interstitial cystitis 10 | 2,312
Osteoporosis 9 | 363
adrenocortical carcinoma 9 | 1,428
esophageal adenocarcinoma 9 | 737
Acquired metabolic disease 8 | 336
Alzheimer's disease 8 | 658
Diabetes Mellitus, Non-Insulin-Dependent 8 | 145
Hemolytic anemia 8 | 77
Liver cancer 8 | 604
Multiple Sclerosis 8 | 540
Obesity 8 | 678
chronic rhinosinusitis 8 | 512
dermatomyositis 8 | 966
gastric carcinoma 8 | 807
mucosa-associated lymphoid tissue lymphoma 8 | 484
primary pancreatic ductal adenocarcinoma 8 | 1,109
Diabetes Mellitus, Type 2 7 | 142
Liver disease 7 | 237
Multiple myeloma 7 | 1,332
Neurodegenerative disease 7 | 414
active ulcerative colitis 7 | 764
fibroadenoma 7 | 559
group 4 medulloblastoma 7 | 1,855
hepatocellular carcinoma 7 | 547
Bipolar Disorder 6 | 666
Coronary artery disease 6 | 268
Crohn's disease 6 | 321
Fatigue 6 | 182
Heart disease 6 | 306
Hypertension 6 | 396
Parkinson's disease 6 | 392
Polycythemia 6 | 25
Skin cancer 6 | 469
Splenomegaly 6 | 190
active Crohn's disease 6 | 922
acute quadriplegic myopathy 6 | 1,158
cutaneous lupus erythematosus 6 | 1,057
juvenile dermatomyositis 6 | 1,187
medulloblastoma 6 | 720
nasopharyngeal carcinoma 6 | 1,058
non primary Sjogren syndrome sicca 6 | 891
posterior fossa group A ependymoma 6 | 468
progressive supranuclear palsy 6 | 676
Arthritis, Rheumatoid 5 | 174
Depressive disorder 5 | 409
Myocardial Ischemia 5 | 169
Prostatic Neoplasms 5 | 495
aldosterone-producing adenoma 5 | 665
primary Sjogren syndrome 5 | 735
sonic hedgehog group medulloblastoma 5 | 467

Tissue

Endocrine System 107 | 18,159
Urinary Tract 107 | 16,678
Digestive Tract 106 | 17,369
Male tissues 106 | 17,142
Female tissues 105 | 17,400
Liver and Pancreas 105 | 16,750
Blood and immune system 103 | 16,909
Nervous System 103 | 16,725
Skin and soft tissues 103 | 17,230
Respiratory system 102 | 16,393
Cardiovascular System 92 | 15,192

Target Family

Non-IDG 56 | 12,091
Enzyme 20 | 4,145
Transcription Factor 15 | 1,400
Kinase 8 | 634
Nuclear Receptor 3 | 48
TF/Epigenetic 3 | 38
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 2 | 408
Ion Channel 1 | 344

GWAS Trait

Hematocrit 113 | 113
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stabilin-1 STAB1 Tbio Non-IDG -1.61013 45.4 107
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Protein TASOR FAM208A Tbio Non-IDG -0.45230 1.33 12
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.73498 53.1 39
Pro-neuregulin-4, membrane-bound isoform NRG4 Tbio Non-IDG -1.33564 24.6 137
Zonadhesin ZAN Tdark Non-IDG 0.00000 0
Histone H1.2 HIST1H1C Tbio Non-IDG -2.01718 95.3 142
Suppression of tumorigenicity 5 protein ST5 Tbio Non-IDG -2.14294 141.9 161
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0
Zinc finger transcription factor Trps1 TRPS1 Tbio Transcription Factor -1.98756 107.0 69