Development Level

Tbio 168 | 10,625
Tdark 39 | 7,003
Tchem 31 | 1,890
Tclin 12 | 602

Collection

Eligible Kinase Proteins 2 | 134
Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 11 | 633
decreased body weight 6 | 174
embryonic lethality prior to t... 6 | 187
preweaning lethality, incomple... 6 | 260
decreased bone mineral content 5 | 157
decreased total body fat amoun... 5 | 186
decreased circulating HDL chol... 4 | 77
decreased lean body mass 4 | 195
abnormal embryo size 3 | 112
decreased circulating choleste... 3 | 85
decreased circulating serum al... 3 | 79
decreased threshold for audito... 3 | 32
embryonic lethality prior to o... 3 | 148
increased circulating alkaline... 3 | 119
increased grip strength 3 | 83
increased total body fat amoun... 3 | 57
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
abnormal testis morphology 2 | 30
abnormal tooth morphology 2 | 24
decreased bone mineral density 2 | 126
decreased circulating aspartat... 2 | 27
decreased circulating free fat... 2 | 39
decreased circulating iron lev... 2 | 25
female infertility 2 | 34
increased body weight 2 | 42
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 107
increased startle reflex 2 | 38
small testis 2 | 37
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal body wall morphology 1 | 7
abnormal coat appearance 1 | 25
abnormal cranium morphology 1 | 32
abnormal embryo turning 1 | 15
abnormal facial morphology 1 | 9
abnormal limb bud morphology 1 | 15
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal radius morphology 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal skin coloration 1 | 18
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal startle reflex 1 | 14
abnormal tail morphology 1 | 17
abnormal tail movements 1 | 12
abnormal ulna morphology 1 | 8
cardiovascular system phenotyp... 1 | 35
cleft palate 1 | 6
convulsive seizures 1 | 11
decreased B cell number 1 | 30
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased circulating LDL chol... 1 | 37
decreased circulating chloride... 1 | 32
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased grip strength 1 | 123
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
embryonic growth retardation 1 | 28
enlarged spleen 1 | 26
fused cornea and lens 1 | 4
hemorrhage 1 | 12
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
male infertility 1 | 62
oligodactyly 1 | 14
persistence of hyaloid vascula... 1 | 22
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
tremors 1 | 34

Disease

ovarian cancer 140 | 8,484
osteosarcoma 136 | 7,933
medulloblastoma, large-cell 114 | 6,234
glioblastoma 101 | 5,572
psoriasis 97 | 6,685
atypical teratoid / rhabdoid tumor 77 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 75 | 3,289
lung cancer 72 | 4,466
Breast cancer 71 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 68 | 2,988
malignant mesothelioma 66 | 3,162
Acquired metabolic disease 65 | 267
pilocytic astrocytoma 61 | 3,086
Carcinoma 60 | 2,147
intraductal papillary-mucinous adenoma (IPMA) 59 | 2,956
primitive neuroectodermal tumor 58 | 3,031
oligodendroglioma 56 | 2,849
invasive ductal carcinoma 55 | 2,950
Cancer 53 | 2,346
lung adenocarcinoma 53 | 2,713
pediatric high grade glioma 53 | 2,712
non-small cell lung cancer 50 | 2,798
ependymoma 44 | 2,514
lung carcinoma 43 | 2,844
subependymal giant cell astrocytoma 43 | 2,287
interstitial cystitis 42 | 2,299
pancreatic cancer 42 | 2,300
group 3 medulloblastoma 39 | 2,254
ductal carcinoma in situ 37 | 1,745
pituitary cancer 37 | 1,972
Pick disease 35 | 1,893
adrenocortical carcinoma 34 | 1,427
adult high grade glioma 34 | 2,148
breast carcinoma 34 | 1,614
ulcerative colitis 34 | 2,087
astrocytoma 33 | 1,493
posterior fossa group A ependymoma 31 | 1,511
group 4 medulloblastoma 30 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,795
primary pancreatic ductal adenocarcinoma 29 | 1,271
sonic hedgehog group medulloblastoma 29 | 1,482
cystic fibrosis 28 | 1,665
astrocytic glioma 27 | 2,241
colon cancer 26 | 1,475
medulloblastoma 26 | 1,524
Rheumatoid Arthritis 25 | 1,160
diabetes mellitus 24 | 1,663
Atopic dermatitis 23 | 944
posterior fossa group B ependymoma 23 | 1,530
tuberculosis 23 | 1,557
gastric carcinoma 20 | 832
Obesity 18 | 616
atypical teratoid/rhabdoid tumor 18 | 1,095
cutaneous lupus erythematosus 18 | 1,056
juvenile dermatomyositis 18 | 1,189
nasopharyngeal carcinoma 16 | 1,056
progressive supranuclear palsy 16 | 674
Multiple myeloma 15 | 1,327
active Crohn's disease 15 | 918
primary Sjogren syndrome 15 | 789
Alzheimer's disease 14 | 644
acute myeloid leukemia 14 | 780
dermatomyositis 14 | 933
spina bifida 14 | 1,064
Amyotrophic Lateral Sclerosis 13 | 431
Endometriosis 13 | 535
Prostatic Neoplasms 13 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
esophageal adenocarcinoma 13 | 737
Down syndrome 12 | 548
Crohn's disease 11 | 304
Schizophrenia 11 | 501
non-small cell lung carcinoma 11 | 413
Peripheral Neuropathy 10 | 303
Polycystic Ovary Syndrome 10 | 332
Waldenstrons macroglobulinemia 10 | 765
aldosterone-producing adenoma 10 | 664
Duchenne muscular dystrophy 9 | 602
Infant length 9 | 11
Mammary Neoplasms 9 | 410
Prostate cancer 9 | 172
acute quadriplegic myopathy 9 | 1,157
pancreatic carcinoma 9 | 567
Cardiovascular system disease 8 | 194
Chronic obstructive pulmonary disease 8 | 146
Intellectual disability 8 | 573
Microcephaly 8 | 149
Multiple Sclerosis 8 | 498
Osteoporosis 8 | 257
fibroadenoma 8 | 557
interstitial lung disease 8 | 291
tuberculosis and treatment for 6 months 8 | 686
Autistic Disorder 7 | 320
Colorectal Neoplasms 7 | 217
Diabetes Mellitus, Non-Insulin-Dependent 7 | 157
Heart disease 7 | 279
IGA Glomerulonephritis 7 | 454
Liver carcinoma 7 | 217
glioblastoma multiforme 7 | 347
gastric cancer 6 | 430

Tissue

Nervous System 247 | 18,561
Blood and immune system 246 | 17,995
Endocrine System 246 | 18,512
Female tissues 246 | 18,647
Urinary Tract 246 | 18,444
Digestive Tract 245 | 18,473
Cardiovascular System 244 | 17,958
Liver and Pancreas 244 | 18,136
Male tissues 244 | 17,969
Respiratory system 241 | 17,484
Skin and soft tissues 241 | 18,115

Target Family

Non-IDG 131 | 11,971
Enzyme 51 | 4,146
Transcription Factor 30 | 1,400
Kinase 15 | 634
Epigenetic 6 | 242
Ion Channel 5 | 341
Transporter 5 | 473
GPCR 4 | 406
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

GWAS Trait

Height 250 | 250
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.21092 1667.7 216
F-actin-capping protein subunit alpha-1 CAPZA1 Tbio Non-IDG -1.28182 20.1 139
Dymeclin DYM Tbio Non-IDG -1.45800 31.6 59
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.94494 110.6 235
Zinc finger protein 367 ZNF367 Tbio Transcription Factor 0.02 1.24 64
Cation channel sperm-associated protein 4 CATSPER4 Tchem Ion Channel 0.06 0.89 32
Fibronectin type III domain-containing protein 3B FNDC3B Tbio Non-IDG -1.29348 21.6 84
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Transcriptional repressor p66-alpha GATAD2A Tbio Non-IDG -0.79314 7.11 142