Development Level

Tbio 20 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased caudal vertebrae num... 2 | 53
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal retinal outer nuclear... 1 | 3
cataract 1 | 92
corneal opacity 1 | 32
decreased grip strength 1 | 116
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased erythrocyte cell num... 1 | 39
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
mydriasis 1 | 6
pallor 1 | 34
prolonged PR interval 1 | 15

Disease

Carcinoma 14 | 11,493
osteosarcoma 14 | 7,950
ovarian cancer 13 | 8,520
medulloblastoma, large-cell 11 | 6,241
psoriasis 11 | 6,694
atypical teratoid / rhabdoid tumor 10 | 5,112
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Breast cancer 9 | 3,578
glioblastoma 9 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung cancer 9 | 4,740
non-small cell lung cancer 9 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Pick disease 7 | 1,894
juvenile dermatomyositis 7 | 1,187
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
Kidney cancer 6 | 2,613
invasive ductal carcinoma 6 | 2,951
lung carcinoma 6 | 2,843
Astrocytoma, Pilocytic 5 | 3,081
Epilepsy 5 | 792
Seizures 5 | 596
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
ependymoma 5 | 4,679
interstitial cystitis 5 | 2,312
primitive neuroectodermal tumor 5 | 3,035
Autosomal recessive predisposition 4 | 1,442
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Muscle hypotonia 4 | 571
Parkinson's disease 4 | 392
acute myeloid leukemia 4 | 783
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
malignant mesothelioma 4 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Alzheimer's disease 3 | 658
Broad flat nasal bridge 3 | 236
Craniofacial Abnormalities 3 | 151
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Intellectual disability 3 | 1,016
Liver Cirrhosis, Experimental 3 | 769
Mammary Neoplasms, Animal 3 | 136
Mammary Neoplasms, Experimental 3 | 154
Nasal bridge wide 3 | 236
Strabismus 3 | 270
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
colon cancer 3 | 1,478
gastric carcinoma 3 | 807
lung adenocarcinoma 3 | 2,716
Anteverted nostril 2 | 191
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Cancer 2 | 2,499
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Failure to gain weight 2 | 365
Gait Ataxia 2 | 51
Hyperreflexia 2 | 209
Hypertension 2 | 396
Hypotonia, severe 2 | 33
Infantile onset 2 | 238
Liver cancer 2 | 604
Liver neoplasms 2 | 130
Myocardial Ischemia 2 | 169
Neurodevelopmental Disorders 2 | 70
Nonsyndromic deafness 2 | 142
Osteoporosis 2 | 363
Pediatric failure to thrive 2 | 365
Polycystic ovary syndrome 2 | 360
Psychotic Disorders 2 | 151
Schizophrenia 2 | 1,160
Stippled epiphyses 2 | 28
Tremor 2 | 113
Upward slant of palpebral fissure 2 | 75
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
head and neck cancer 2 | 271
limb girdle muscular dystrophy 2A 2 | 213
nephrosclerosis 2 | 333
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
pterygium 2 | 76
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Blood and immune system 21 | 16,909
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 14 | 12,091
Transcription Factor 4 | 1,400
Enzyme 3 | 4,145
Transporter 1 | 473

GWAS Trait

Hand grip strength 22 | 22
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.80099 639.3 247
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Zinc finger and BTB domain-containing protein 21 ZBTB21 Tbio Transcription Factor -0.50515 3.18 58
Homeobox protein Hox-B3 HOXB3 Tbio Transcription Factor -1.64244 41.9 120
Zinc finger protein GLIS1 GLIS1 Tbio Transcription Factor -0.99864 11.4 101
Protein turtle homolog B IGSF9B Tdark Non-IDG -0.38803 2.21 17
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 GBF1 Tbio Non-IDG -0.60758 4.31 61
Deleted in esophageal cancer 1 DEC1 Tbio Non-IDG -0.67210 6.20 4
Peroxisomal membrane protein PEX14 PEX14 Tbio Non-IDG -1.56143 37.1 205