Development Level

Tbio 42 | 11,445
Tchem 12 | 1,598
Tdark 8 | 6,588
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 2 | 220
abnormal retina morphology 2 | 71
decreased circulating triglyce... 2 | 79
hyperactivity 2 | 148
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal colon morphology 1 | 3
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal ileum morphology 1 | 2
abnormal outer ear morphology 1 | 3
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
absent optic nerve 1 | 2
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased CD4-positive, CD25-p... 1 | 1
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased cardiac muscle contr... 1 | 8
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased effector memory CD4-... 1 | 1
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
prolonged PQ interval 1 | 5
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
short tibia 1 | 97
small testis 1 | 58
thrombocytosis 1 | 27

Disease

Carcinoma 52 | 11,493
ovarian cancer 41 | 8,520
osteosarcoma 38 | 7,950
glioblastoma 34 | 5,792
medulloblastoma, large-cell 28 | 6,241
lung cancer 27 | 4,740
psoriasis 27 | 6,694
oligodendroglioma 25 | 2,850
atypical teratoid / rhabdoid tumor 24 | 5,112
ependymoma 24 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
lung carcinoma 21 | 2,843
Breast cancer 20 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
invasive ductal carcinoma 19 | 2,951
Kidney cancer 18 | 2,613
adult high grade glioma 17 | 3,801
astrocytic glioma 17 | 2,597
malignant mesothelioma 17 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Atherosclerosis 16 | 291
Coronary artery disease 16 | 268
Lipid metabolism disorder 16 | 114
diabetes mellitus 16 | 1,728
Astrocytoma, Pilocytic 15 | 3,081
tuberculosis 15 | 2,010
ulcerative colitis 15 | 1,819
Obesity 14 | 678
ductal carcinoma in situ 14 | 1,745
interstitial cystitis 14 | 2,312
subependymal giant cell astrocytoma 14 | 2,287
Cardiovascular system disease 13 | 246
lung adenocarcinoma 13 | 2,716
primitive neuroectodermal tumor 13 | 3,035
Type 2 diabetes mellitus 12 | 272
adrenocortical carcinoma 12 | 1,428
astrocytoma 12 | 1,146
dermatomyositis 12 | 966
group 3 medulloblastoma 12 | 4,104
non-small cell lung cancer 12 | 2,890
Cancer 11 | 2,499
Rheumatoid arthritis 11 | 1,191
Acquired metabolic disease 10 | 336
Schizophrenia 10 | 1,160
group 4 medulloblastoma 10 | 1,855
active ulcerative colitis 9 | 764
acute quadriplegic myopathy 9 | 1,158
breast carcinoma 9 | 1,638
colon cancer 9 | 1,478
pancreatic cancer 9 | 2,398
Alzheimer's disease 8 | 658
Metabolic syndrome X 8 | 52
Pick disease 8 | 1,894
Autosomal recessive predisposition 7 | 1,442
Duchenne muscular dystrophy 7 | 601
Intellectual disability 7 | 1,016
Liver Cirrhosis, Experimental 7 | 769
cystic fibrosis 7 | 1,696
juvenile dermatomyositis 7 | 1,187
mucosa-associated lymphoid tissue lymphoma 7 | 484
pituitary cancer 7 | 1,972
Atopic dermatitis 6 | 952
Hypercholesterolemia, Familial 6 | 23
Hypertension 6 | 396
Vascular disease 6 | 319
active Crohn's disease 6 | 922
aldosterone-producing adenoma 6 | 665
cutaneous lupus erythematosus 6 | 1,057
fibroadenoma 6 | 559
pediatric high grade glioma 6 | 1,064
progressive supranuclear palsy 6 | 676
Amyotrophic lateral sclerosis 5 | 451
Crohn's disease 5 | 321
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
Dyslipidemias 5 | 27
Hyperlipoproteinemia Type II 5 | 12
Hypertensive disease 5 | 292
Hypertriglyceridemia 5 | 17
Kidney disease 5 | 430
Peripheral vascular disease 5 | 87
Prostatic Neoplasms 5 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
primary pancreatic ductal adenocarcinoma 5 | 1,109
Anemia 4 | 365
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Colorectal Neoplasms 4 | 243
Heart failure 4 | 162
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Mood Disorders 4 | 184
Waldenstrons macroglobulinemia 4 | 765
esophageal adenocarcinoma 4 | 737
hepatocellular carcinoma 4 | 547
limb girdle muscular dystrophy 2A 4 | 213
nasopharyngeal carcinoma 4 | 1,058
non diabetic and post-ischemic heart failure 4 | 200
spina bifida 4 | 1,074

Tissue

Digestive Tract 63 | 17,369
Endocrine System 63 | 18,159
Female tissues 63 | 17,400
Liver and Pancreas 63 | 16,750
Skin and soft tissues 63 | 17,230
Male tissues 62 | 17,142
Blood and immune system 61 | 16,909
Respiratory system 61 | 16,393
Urinary Tract 61 | 16,678
Cardiovascular System 60 | 15,192
Nervous System 60 | 16,725

Target Family

Non-IDG 34 | 12,091
Enzyme 17 | 4,145
Transcription Factor 6 | 1,400
Transporter 3 | 473
Kinase 2 | 634
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48
oGPCR 1 | 421

GWAS Trait

HDL cholesterol levels 66 | 66
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-13 SNX13 Tbio Non-IDG -0.67169 5.24 65
MAP kinase-activating death domain protein MADD Tbio Enzyme -1.86555 79.6 121
Stabilin-1 STAB1 Tbio Non-IDG -1.61013 45.4 107
Scavenger receptor cysteine-rich type 1 protein M130 CD163 Tbio Non-IDG -2.93036 825.2 985
R3H domain-containing protein 2 R3HDM2 Tdark Non-IDG -0.82119 4.93 39
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
GPI mannosyltransferase 2 PIGV Tbio Enzyme -1.07565 13.4 71
Zinc finger transcription factor Trps1 TRPS1 Tbio Transcription Factor -1.98756 107.0 69
Probable E3 ubiquitin-protein ligase HECTD4 HECTD4 Tbio Enzyme -1.02570 11.0 0
Solute carrier family 12 member 4 SLC12A4 Tbio Transporter -1.72121 47.9 119