Development Level

Tbio 9 | 11,445
Tdark 5 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased circulating aspartat... 1 | 34
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
increased circulating triglyce... 1 | 42
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 12 | 11,493
ovarian cancer 9 | 8,520
glioblastoma 6 | 5,792
Kidney cancer 5 | 2,613
atypical teratoid / rhabdoid tumor 5 | 5,112
lung carcinoma 5 | 2,843
osteosarcoma 5 | 7,950
Breast cancer 4 | 3,578
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
lung cancer 4 | 4,740
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Astrocytoma, Pilocytic 3 | 3,081
Melanoma 3 | 711
astrocytic glioma 3 | 2,597
ependymoma 3 | 4,679
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
pituitary cancer 3 | 1,972
psoriasis 3 | 6,694
Cancer 2 | 2,499
Depressive disorder 2 | 409
Essential tremor 2 | 28
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
cystic fibrosis 2 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non-small cell lung cancer 2 | 2,890
substance-related disorder 2 | 162
tuberculosis 2 | 2,010
Abnormal ocular motility 1 | 19
Acquired metabolic disease 1 | 336
Adenocarcinoma of lung 1 | 142
Adenocarcinoma of lung (disorder) 1 | 60
Alcoholic Intoxication, Chronic 1 | 289
Anemia, Hemolytic 1 | 55
Anxiety 1 | 136
Anxiety disease 1 | 113
Ataxia, Spinocerebellar 1 | 16
Atrophy of cerebellum 1 | 103
Autosomal dominant cerebellar ataxia 1 | 33
Autosomal recessive nonsyndromic deafness 98 1 | 4
Azoospermia 1 | 110
Brain cancer 1 | 30
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Renal Cell 1 | 124
Cell Transformation, Neoplastic 1 | 97
Cerebellar Dysmetria 1 | 56
Cerebellar degeneration 1 | 103
Cerebral atrophy 1 | 178
Colorectal cancer 1 | 25
Congenital hemolytic anemia 1 | 32
Delusions 1 | 11
Dementia 1 | 175
Diffuse large B-cell lymphoma 1 | 39
Dysarthria 1 | 192
Dysdiadochokinesis 1 | 25
Familial adenomatous polyposis 1 | 32
Friedreich ataxia 1 | 24
Hereditary elliptocytosis 1 | 22
Hereditary spherocytosis 1 | 16
Hyperreflexia 1 | 209
Hyperuricemia 1 | 49
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Icterus 1 | 82
Increased bilirubin level (finding) 1 | 18
Inflammatory myofibroblastic tumor 1 | 8
Infratentorial atrophy 1 | 103
Liver cancer 1 | 604
Machado-Joseph disease 1 | 18
Malformed pinnae 1 | 37
Neoplasm Metastasis 1 | 168
Neoplasm Recurrence, Local 1 | 37
Neoplastic Cell Transformation 1 | 89
Nervous System Neoplasms 1 | 8
Neurodegenerative disease 1 | 414
Neuropathy 1 | 261
Papillary thyroid carcinoma 1 | 43
Parkinsonian Disorders 1 | 56
Pendred Syndrome 1 | 22
Peripheral sensorimotor neuropathy 1 | 16
Plasma Cell Granuloma, Pulmonary 1 | 2
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Progressive cerebellar ataxia 1 | 13
Renal Cell Carcinoma 1 | 214
Spinocerebellar Ataxias 1 | 34
Spinocerebellar ataxia type 1 1 | 16
Spinocerebellar ataxia type 8 1 | 7
Werner syndrome 1 | 29
dentatorubral-pallidoluysian atrophy 1 | 21
non-small cell lung carcinoma 1 | 317
primary open angle glaucoma 1 | 16
type I diabetes mellitus 1 | 22

Tissue

Endocrine System 15 | 18,159
Digestive Tract 14 | 17,369
Female tissues 14 | 17,400
Male tissues 14 | 17,142
Blood and immune system 13 | 16,909
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192
Liver and Pancreas 12 | 16,750

Target Family

Non-IDG 13 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634
Transporter 1 | 473

GWAS Trait

Granulocyte-colony stimulating... 16 | 16
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

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