Development Level

Tbio 102 | 11,445
Tchem 26 | 1,598
Tdark 21 | 6,588
Tclin 13 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 6 | 499
abnormal behavior 5 | 298
decreased lean body mass 5 | 135
prenatal lethality prior to he... 4 | 87
abnormal bone structure 3 | 187
abnormal seminal vesicle morph... 3 | 114
decreased bone mineral content 3 | 151
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
hypoactivity 3 | 132
increased circulating calcium ... 3 | 34
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
abnormal embryo size 2 | 220
abnormal gait 2 | 69
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased heart weight 2 | 27
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased circulating total pr... 2 | 28
increased erythrocyte cell num... 2 | 39
increased heart rate 2 | 23
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
short tibia 2 | 97
thrombocytopenia 2 | 56
abnormal body wall morphology 1 | 9
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal heart left ventricle ... 1 | 16
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
decreased IgG1 level 1 | 8
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating creatine... 1 | 4
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased vertical activity 1 | 24
limb grasping 1 | 41
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 103 | 11,493
osteosarcoma 94 | 7,950
ovarian cancer 91 | 8,520
glioblastoma 70 | 5,792
psoriasis 69 | 6,694
lung cancer 67 | 4,740
medulloblastoma, large-cell 62 | 6,241
invasive ductal carcinoma 49 | 2,951
Cancer 46 | 2,499
atypical teratoid / rhabdoid tumor 46 | 5,112
ependymoma 44 | 4,679
tuberculosis 44 | 2,010
Breast cancer 43 | 3,578
group 3 medulloblastoma 42 | 4,104
malignant mesothelioma 42 | 3,232
lung carcinoma 41 | 2,843
pancreatic cancer 41 | 2,398
non-small cell lung cancer 40 | 2,890
adult high grade glioma 38 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,989
primitive neuroectodermal tumor 37 | 3,035
lung adenocarcinoma 36 | 2,716
Astrocytoma, Pilocytic 35 | 3,081
interstitial cystitis 35 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,955
Rheumatoid arthritis 32 | 1,191
oligodendroglioma 30 | 2,850
breast carcinoma 29 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
ulcerative colitis 28 | 1,819
Kidney cancer 27 | 2,613
astrocytic glioma 27 | 2,597
cystic fibrosis 26 | 1,696
ductal carcinoma in situ 26 | 1,745
pituitary cancer 26 | 1,972
subependymal giant cell astrocytoma 26 | 2,287
acute quadriplegic myopathy 24 | 1,158
juvenile dermatomyositis 23 | 1,187
Multiple myeloma 22 | 1,332
Pick disease 22 | 1,894
cutaneous lupus erythematosus 22 | 1,057
diabetes mellitus 22 | 1,728
dermatomyositis 21 | 966
group 4 medulloblastoma 20 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
colon cancer 17 | 1,478
primary pancreatic ductal adenocarcinoma 17 | 1,109
Waldenstrons macroglobulinemia 16 | 765
Atopic dermatitis 15 | 952
Autosomal recessive predisposition 15 | 1,442
adrenocortical carcinoma 15 | 1,428
hepatocellular carcinoma 15 | 547
Asthma 14 | 385
Intellectual disability 14 | 1,016
Liver Cirrhosis, Experimental 14 | 769
Obesity 14 | 678
astrocytoma 14 | 1,146
esophageal adenocarcinoma 14 | 737
medulloblastoma 14 | 720
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
pancreatic carcinoma 13 | 562
pediatric high grade glioma 13 | 1,064
primary Sjogren syndrome 13 | 735
Crohn's disease 12 | 321
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
acute myeloid leukemia 12 | 783
gastric carcinoma 12 | 807
non primary Sjogren syndrome sicca 12 | 891
Multiple Sclerosis 11 | 540
active Crohn's disease 11 | 922
active ulcerative colitis 11 | 764
mucosa-associated lymphoid tissue lymphoma 11 | 484
Acquired metabolic disease 10 | 336
Muscle hypotonia 10 | 571
Schizophrenia 10 | 1,160
progressive supranuclear palsy 10 | 676
spina bifida 10 | 1,074
Arthritis 9 | 290
Arthritis, Rheumatoid 9 | 174
Atherosclerosis 9 | 291
Leukemia, Myelocytic, Acute 9 | 120
Prostatic Neoplasms 9 | 495
aldosterone-producing adenoma 9 | 665
Alzheimer's disease 8 | 658
Bipolar Disorder 8 | 666
Breast Neoplasms 8 | 445
Chronic Lymphocytic Leukemia 8 | 262
Coronary artery disease 8 | 268
Down syndrome 8 | 499
Duchenne muscular dystrophy 8 | 601
Kidney disease 8 | 430
Lymphoid leukemia 8 | 160
Mammary Neoplasms 8 | 425
Type 2 diabetes mellitus 8 | 272
nasopharyngeal carcinoma 8 | 1,058
posterior fossa group A ependymoma 8 | 468

Tissue

Endocrine System 157 | 18,159
Digestive Tract 156 | 17,369
Female tissues 156 | 17,400
Blood and immune system 155 | 16,909
Skin and soft tissues 155 | 17,230
Liver and Pancreas 154 | 16,750
Nervous System 154 | 16,725
Respiratory system 153 | 16,393
Male tissues 152 | 17,142
Urinary Tract 152 | 16,678
Cardiovascular System 149 | 15,192

Target Family

Non-IDG 82 | 12,091
Transcription Factor 25 | 1,400
Enzyme 23 | 4,145
GPCR 11 | 408
Kinase 9 | 634
Epigenetic 7 | 242
Transporter 3 | 473
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

GWAS Trait

Granulocyte percentage of myel... 162 | 162
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
T-complex protein 11 homolog TCP11 Tbio Non-IDG -1.26152 18.0 80
ATPase family AAA domain-containing protein 5 ATAD5 Tbio Enzyme -1.60534 42.9 117
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149
Nuclear factor 1 X-type NFIX Tbio Transcription Factor -1.70265 49.7 74
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94
Polycomb group RING finger protein 3 PCGF3 Tdark Non-IDG -0.48328 1.97 115
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0