Development Level

Tbio 6 | 11,445
Tdark 3 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased heart rate 1 | 23
small testis 1 | 58

Disease

ovarian cancer 8 | 8,520
Carcinoma 7 | 11,493
medulloblastoma, large-cell 7 | 6,241
ependymoma 6 | 4,679
atypical teratoid / rhabdoid tumor 5 | 5,112
lung carcinoma 5 | 2,843
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
cystic fibrosis 4 | 1,696
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primitive neuroectodermal tumor 4 | 3,035
Alzheimer's disease 3 | 658
Breast cancer 3 | 3,578
Metabolic syndrome X 3 | 52
Pick disease 3 | 1,894
active ulcerative colitis 3 | 764
adult high grade glioma 3 | 3,801
glioblastoma 3 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung cancer 3 | 4,740
pituitary cancer 3 | 1,972
Atopic dermatitis 2 | 952
Carcinoma, Renal Cell 2 | 124
Chemical and Drug Induced Liver Injury 2 | 195
Colorectal Neoplasms 2 | 243
Kidney cancer 2 | 2,613
Obesity 2 | 678
Renal Cell Carcinoma 2 | 214
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Umbilical hernia 2 | 93
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287
Acquired metabolic disease 1 | 336
Alcoholic Intoxication, Chronic 1 | 289
Atrial Fibrillation 1 | 124
Autism spectrum disorder 1 | 101
Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder) 1 | 4
Axial hypotonia 1 | 46
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Cardiomyopathies 1 | 110
Cardiovascular system disease 1 | 246
Childhood onset 1 | 38
Cocaine-Related Disorders 1 | 92
Conduction disorder of the heart 1 | 79
Creatine phosphokinase serum increased 1 | 110
EKG abnormalities 1 | 78
EMERY-DREIFUSS MUSCULAR DYSTROPHY 5, AUTOSOMAL DOMINANT 1 | 1
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Elevated creatine kinase 1 | 110
Emery-Dreifuss muscular dystrophy 1 | 23
Epilepsy 1 | 792
Heart conduction disease 1 | 83
Heart disease 1 | 306
Hernia, Inguinal 1 | 89
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hyperreflexia 1 | 209
Hypokinesia 1 | 19
Infantile onset 1 | 238
Large intestine cancer 1 | 126
Lipid metabolism disorder 1 | 114
Lipid storage disease 1 | 8
Liver cancer 1 | 604
Muscle Hypertonia 1 | 88
Muscle atrophy, proximal 1 | 11
Muscle biopsy shows dystrophic changes 1 | 39
Muscular Dystrophy, Emery-Dreifuss 1 | 5
Muscular dystrophy 1 | 75
Myoclonus 1 | 74
Osteoporosis 1 | 363
Paronychia 1 | 7
Phenotypic variability 1 | 150
Polymicrogyria 1 | 48
Poor eye contact 1 | 12
Proximal muscle weakness 1 | 47
Proximal neurogenic muscle weakness 1 | 47
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Seizures 1 | 596
Stiff-Person syndrome 1 | 12
Stomach Neoplasms 1 | 300
Vasculogenic impotence 1 | 1
active Crohn's disease 1 | 922
atypical teratoid/rhabdoid tumor 1 | 357
facioscapulohumeral dystrophy 1 | 288
glioblastoma multiforme 1 | 142
posterior fossa group A ependymoma 1 | 468

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 5 | 12,091
Enzyme 4 | 4,145
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

GWAS Trait

Glycerophospholipid levels 11 | 11
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Fatty acid desaturase 2 FADS2 Tbio Enzyme -2.55411 349.6 135
Transmembrane protein 258 TMEM258 Tdark Non-IDG -0.35218 2.02 6
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Transmembrane protein 229B TMEM229B Tdark Non-IDG 0.61 0.28 4
Pyridoxal-dependent decarboxylase domain-containing protein 1 PDXDC1 Tdark Enzyme -0.23066 2.38 128
Gephyrin GPHN Tbio Non-IDG -2.56617 383.9 235
Polycystic kidney disease 2-like 1 protein PKD2L1 Tchem Ion Channel -1.95186 96.8 100
Myelin regulatory factor MYRF Tbio Transcription Factor -2.68286 462.0 31
Serine palmitoyltransferase 3 SPTLC3 Tbio Enzyme -1.26166 18.5 24