Development Level

Tbio 43 | 11,178
Tchem 10 | 1,885
Tdark 6 | 6,569
Tclin 2 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 3 | 298
abnormal eye morphology 3 | 68
enlarged heart 3 | 210
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal epididymis morphology 2 | 42
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased bone mineral density 2 | 126
decreased circulating insulin ... 2 | 76
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal incisor color 1 | 3
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal motor capabilities-co... 1 | 5
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
embryonic growth retardation 1 | 106
eyelids fail to open 1 | 3
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating aspartat... 1 | 15
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
kyphosis 1 | 5
long tibia 1 | 25
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small testis 1 | 58
thin ventricular wall 1 | 24
urinary bladder obstruction 1 | 4

Disease

Carcinoma 41 | 11,192
psoriasis 27 | 6,514
ovarian cancer 23 | 8,297
osteosarcoma 21 | 7,766
Type 2 diabetes mellitus 20 | 268
glioblastoma 18 | 5,635
medulloblastoma, large-cell 16 | 6,086
Acquired metabolic disease 14 | 329
Breast cancer 14 | 3,469
atypical teratoid / rhabdoid tumor 14 | 4,971
diabetes mellitus 14 | 1,683
lung cancer 14 | 4,607
group 3 medulloblastoma 13 | 4,002
primitive neuroectodermal tumor 13 | 2,957
Astrocytoma, Pilocytic 12 | 3,006
Diabetes Mellitus, Non-Insulin-Dependent 12 | 140
Diabetes Mellitus, Type 2 12 | 136
Kidney cancer 12 | 2,548
Schizophrenia 11 | 1,136
malignant mesothelioma 11 | 3,135
Autosomal recessive predisposition 10 | 1,407
ependymoma 10 | 4,559
adult high grade glioma 9 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,204
Cancer 8 | 2,388
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,872
invasive ductal carcinoma 8 | 2,867
non-small cell lung cancer 8 | 2,799
pituitary cancer 8 | 1,915
Diabetes Mellitus, Noninsulin-Dependent 7 | 31
Metabolic syndrome X 7 | 52
oligodendroglioma 7 | 2,768
pancreatic cancer 7 | 2,322
pediatric high grade glioma 7 | 1,035
ulcerative colitis 7 | 1,765
Anemia 6 | 353
Diabetes Mellitus, Experimental 6 | 101
Epilepsy 6 | 775
Insulinoma 6 | 24
Obesity 6 | 655
Rheumatoid arthritis 6 | 1,156
breast carcinoma 6 | 1,589
ductal carcinoma in situ 6 | 1,686
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,902
lung carcinoma 6 | 2,755
primary pancreatic ductal adenocarcinoma 6 | 1,071
tuberculosis 6 | 1,963
Cognitive delay 5 | 596
Depressive disorder 5 | 401
Gestational diabetes 5 | 26
Global developmental delay 5 | 596
Hemolytic anemia 5 | 73
Hyperglycemia 5 | 134
Mental and motor retardation 5 | 596
Multiple myeloma 5 | 1,296
Peripheral vascular disease 5 | 81
Reticulocytosis 5 | 20
Seizures 5 | 584
astrocytic glioma 5 | 2,530
cystic fibrosis 5 | 1,629
lung adenocarcinoma 5 | 2,627
subependymal giant cell astrocytoma 5 | 2,230
Amyotrophic lateral sclerosis 4 | 437
Anemia, Hemolytic 4 | 55
Atopic dermatitis 4 | 915
Bipolar Disorder 4 | 646
Cardiovascular system disease 4 | 240
Cholelithiasis 4 | 33
Congenital hemolytic anemia 4 | 32
Diarrhea 4 | 245
Failure to gain weight 4 | 359
Hepatomegaly 4 | 280
Icterus 4 | 81
Neuropathy 4 | 254
Osteoporosis 4 | 348
Pediatric failure to thrive 4 | 359
Splenomegaly 4 | 186
active ulcerative colitis 4 | 736
esophageal adenocarcinoma 4 | 696
group 4 medulloblastoma 4 | 1,806
interstitial cystitis 4 | 2,237
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,911
Alcoholic Intoxication, Chronic 3 | 283
Asthma 3 | 370
Dysarthria 3 | 190
Essential Hypertension 3 | 92
Hypertension 3 | 372
Liver carcinoma 3 | 229
Major Depressive Disorder 3 | 293
Mental Depression 3 | 325
Neurodegenerative disease 3 | 402
Pick disease 3 | 1,856
Retinal Diseases 3 | 54
active Crohn's disease 3 | 882
acute quadriplegic myopathy 3 | 1,133
adrenocortical carcinoma 3 | 1,385
atypical teratoid/rhabdoid tumor 3 | 349
gastric carcinoma 3 | 781
sonic hedgehog group medulloblastoma 3 | 459
spina bifida 3 | 1,053

Tissue

Endocrine System 57 | 18,159
Digestive Tract 55 | 17,369
Liver and Pancreas 55 | 16,750
Skin and soft tissues 54 | 17,230
Female tissues 53 | 17,400
Blood and immune system 52 | 16,909
Urinary Tract 52 | 16,678
Nervous System 51 | 16,725
Male tissues 50 | 17,142
Respiratory system 50 | 16,393
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 25 | 12,091
Enzyme 15 | 4,145
Transcription Factor 7 | 1,400
Transporter 5 | 473
Kinase 4 | 634
Ion Channel 3 | 344
Epigenetic 1 | 242
GPCR 1 | 408

GWAS Trait

Glycated hemoglobin levels 61 | 61
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bile salt export pump ABCB11 Tchem Transporter -2.84131 702.2 144
Homeobox protein SIX3 SIX3 Tbio Transcription Factor -2.84681 686.8 212
Glucose-6-phosphatase 2 G6PC2 Tbio Enzyme -1.88404 87.7 44
Ceramide synthase 2 CERS2 Tbio Transcription Factor -1.82917 76.3 154
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 ARAP1 Tbio Non-IDG -0.99923 14.5 99
Histo-blood group ABO system transferase ABO Tchem Enzyme 0.00000 0
Fatty acid desaturase 2 FADS2 Tchem Enzyme -2.55411 349.6 135
Unconventional myosin-IXb MYO9B Tbio Non-IDG -1.68591 55.7 79
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
Sodium-dependent phosphate transporter 2 SLC20A2 Tbio Transporter -2.29276 197.3 107