Development Level

Tbio 32 | 11,445
Tdark 9 | 6,588
Tchem 7 | 1,598
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal coat-hair pigmentatio... 3 | 64
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal humerus morphology 1 | 11
abnormal maxilla morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
absent teeth 1 | 3
cataract 1 | 92
decreased circulating alkaline... 1 | 46
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
impaired pupillary reflex 1 | 26
increased circulating potassiu... 1 | 29
increased coping response 1 | 4
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
prenatal lethality prior to he... 1 | 87
prolonged ST segment 1 | 36
vertebral fusion 1 | 23

Disease

Carcinoma 41 | 11,493
ovarian cancer 29 | 8,520
osteosarcoma 27 | 7,950
medulloblastoma, large-cell 25 | 6,241
lung cancer 23 | 4,740
psoriasis 22 | 6,694
glioblastoma 20 | 5,792
atypical teratoid / rhabdoid tumor 19 | 5,112
Astrocytoma, Pilocytic 18 | 3,081
Kidney cancer 18 | 2,613
ependymoma 18 | 4,679
adult high grade glioma 16 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
oligodendroglioma 15 | 2,850
lung carcinoma 14 | 2,843
Cancer 13 | 2,499
group 3 medulloblastoma 13 | 4,104
group 4 medulloblastoma 13 | 1,855
interstitial cystitis 13 | 2,312
non-small cell lung cancer 13 | 2,890
primitive neuroectodermal tumor 13 | 3,035
astrocytic glioma 12 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
subependymal giant cell astrocytoma 12 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung adenocarcinoma 11 | 2,716
Breast cancer 10 | 3,578
invasive ductal carcinoma 10 | 2,951
malignant mesothelioma 10 | 3,232
pituitary cancer 10 | 1,972
tuberculosis 10 | 2,010
ductal carcinoma in situ 9 | 1,745
pancreatic cancer 9 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
ulcerative colitis 8 | 1,819
Diabetes Mellitus, Non-Insulin-Dependent 7 | 145
Diabetes Mellitus, Type 2 7 | 142
Schizophrenia 7 | 1,160
active ulcerative colitis 7 | 764
acute quadriplegic myopathy 7 | 1,158
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
diabetes mellitus 7 | 1,728
Type 2 diabetes mellitus 6 | 272
Vascular disease 6 | 319
pediatric high grade glioma 6 | 1,064
Acquired metabolic disease 5 | 336
Crohn's disease 5 | 321
Endometrial cancer 5 | 311
Melanoma 5 | 711
Pick disease 5 | 1,894
adrenocortical carcinoma 5 | 1,428
nasopharyngeal carcinoma 5 | 1,058
non primary Sjogren syndrome sicca 5 | 891
Alzheimer's disease 4 | 658
Cardiovascular system disease 4 | 246
Gestational diabetes 4 | 26
Liver cancer 4 | 604
Prostatic Neoplasms 4 | 495
Skin cancer 4 | 469
astrocytoma 4 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cutaneous lupus erythematosus 4 | 1,057
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547
juvenile dermatomyositis 4 | 1,187
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Depressive disorder 3 | 409
Diabetes Mellitus, Experimental 3 | 108
Diabetes Mellitus, Noninsulin-Dependent 3 | 31
Disease of mental health 3 | 36
Epilepsy 3 | 792
Esophageal Neoplasms 3 | 69
Kidney disease 3 | 430
Lymphoma 3 | 81
Mental Depression 3 | 333
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Polycystic ovary syndrome 3 | 360
Systemic lupus erythematosus 3 | 194
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
chronic rhinosinusitis 3 | 512
esophageal adenocarcinoma 3 | 737
facioscapulohumeral dystrophy 3 | 288
non-small cell lung carcinoma 3 | 317
periodontitis 3 | 293
primary Sjogren syndrome 3 | 735
progressive supranuclear palsy 3 | 676
Arthritis, Juvenile 2 | 126
Attention deficit hyperactivity disorder 2 | 278
Endometriosis 2 | 540
Juvenile arthritis 2 | 126
dermatomyositis 2 | 966
fibroadenoma 2 | 559
urothelial carcinoma 2 | 318

Tissue

Endocrine System 52 | 18,159
Female tissues 52 | 17,400
Blood and immune system 51 | 16,909
Skin and soft tissues 51 | 17,230
Urinary Tract 51 | 16,678
Digestive Tract 50 | 17,369
Male tissues 50 | 17,142
Nervous System 50 | 16,725
Respiratory system 50 | 16,393
Liver and Pancreas 48 | 16,750
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 8 | 4,145
Kinase 5 | 634
Transcription Factor 4 | 1,400
Transporter 4 | 473
GPCR 3 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344

GWAS Trait

Glucose homeostasis traits 52 | 52
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
HAUS augmin-like complex subunit 2 HAUS2 Tbio Non-IDG 0.71 0.12 44
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 SOHLH2 Tbio Transcription Factor -1.26578 21.4 126
Zinc finger ZZ-type and EF-hand domain-containing protein 1 ZZEF1 Tdark Non-IDG 0.19 0.86 20
P2Y purinoceptor 2 P2RY2 Tclin GPCR -2.74629 565.7 192
Lipoma-preferred partner LPP Tbio Non-IDG -2.77949 582.6 164
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
ALK tyrosine kinase receptor ALK Tclin Kinase -3.44312 2942.9 976
Receptor-type tyrosine-protein phosphatase mu PTPRM Tchem Enzyme -1.84748 71.7 144
Calcium uptake protein 3, mitochondrial MICU3 Tdark Non-IDG -0.21085 1.14 50