Development Level

Tbio 20 | 11,445
Tdark 7 | 6,588
Tchem 4 | 1,598
Tclin 4 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
increased bone mineral content 2 | 108
abnormal facial morphology 1 | 17
abnormal limb bud morphology 1 | 17
abnormal placenta vasculature 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal spine curvature 1 | 9
abnormal vocalization 1 | 21
cyanosis 1 | 7
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased fluid intake 1 | 3
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
embryonic lethality prior to t... 1 | 278
fusion of vertebral arches 1 | 7
hemorrhage 1 | 23
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
kyphosis 1 | 5
prenatal lethality 1 | 28
respiratory system phenotype 1 | 2
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 33 | 11,493
osteosarcoma 21 | 7,950
Kidney disease 20 | 430
ovarian cancer 19 | 8,520
psoriasis 15 | 6,694
Breast cancer 12 | 3,578
glioblastoma 12 | 5,792
medulloblastoma, large-cell 11 | 6,241
Gout 10 | 106
atypical teratoid / rhabdoid tumor 10 | 5,112
lung cancer 10 | 4,740
malignant mesothelioma 10 | 3,232
pancreatic cancer 10 | 2,398
Kidney cancer 9 | 2,613
adult high grade glioma 8 | 3,801
ependymoma 8 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
non-small cell lung cancer 8 | 2,890
subependymal giant cell astrocytoma 8 | 2,287
Cancer 7 | 2,499
Pick disease 7 | 1,894
group 3 medulloblastoma 7 | 4,104
lung carcinoma 7 | 2,843
primary pancreatic ductal adenocarcinoma 7 | 1,109
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
Astrocytoma, Pilocytic 5 | 3,081
Autosomal recessive predisposition 5 | 1,442
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
nephrosclerosis 5 | 333
ulcerative colitis 5 | 1,819
Kidney Diseases 4 | 114
adrenocortical carcinoma 4 | 1,428
cystic fibrosis 4 | 1,696
cystic fibrosis and chronic rhinosinusitis 4 | 214
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
invasive ductal carcinoma 4 | 2,951
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
tuberculosis 4 | 2,010
Acquired metabolic disease 3 | 336
Atopic dermatitis 3 | 952
Atrial Fibrillation 3 | 124
Duchenne muscular dystrophy 3 | 601
Epilepsy 3 | 792
Melanoma 3 | 711
Obesity 3 | 678
Rheumatoid arthritis 3 | 1,191
active Crohn's disease 3 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
group 4 medulloblastoma 3 | 1,855
spina bifida 3 | 1,074
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Atherosclerosis 2 | 291
Becker muscular dystrophy 2 | 191
Bipolar Disorder 2 | 666
Cardiomyopathy 2 | 116
Constipation 2 | 181
Crohn's disease 2 | 321
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Endometriosis 2 | 540
Familial atrial fibrillation 2 | 23
Glaucoma 2 | 239
Kidney Failure 2 | 111
Liver Cirrhosis, Experimental 2 | 769
Multiple myeloma 2 | 1,332
Osteoporosis 2 | 363
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Respiratory Insufficiency 2 | 132
Skin cancer 2 | 469
Type 2 diabetes mellitus 2 | 272
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
limb girdle muscular dystrophy 2A 2 | 213
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
periodontitis 2 | 293
primary Sjogren syndrome 2 | 735
progressive supranuclear palsy 2 | 676

Tissue

Digestive Tract 35 | 17,369
Endocrine System 35 | 18,159
Female tissues 35 | 17,400
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Nervous System 34 | 16,725
Blood and immune system 33 | 16,909
Respiratory system 32 | 16,393
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 17 | 12,091
Enzyme 7 | 4,145
Transcription Factor 4 | 1,400
Transporter 4 | 473
Ion Channel 2 | 344
Kinase 1 | 634

GWAS Trait

Glomerular filtration rate in ... 35 | 35
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
Stanniocalcin-1 STC1 Tbio Non-IDG -2.88941 780.1 269
Uromodulin UMOD Tbio Non-IDG -2.74963 574.6 423
Nuclear factor of activated T-cells, cytoplasmic 1 NFATC1 Tbio Transcription Factor -2.75732 525.1 391
DNA helicase INO80 INO80 Tbio Enzyme -2.54124 327.2 47
Dachshund homolog 1 DACH1 Tbio Non-IDG -2.51016 323.1 190
Dipeptidase 1 DPEP1 Tclin Enzyme -2.47338 295.7 145
Sodium- and chloride-dependent GABA transporter 2 SLC6A13 Tchem Transporter -2.43015 259.2 51
Carbamoyl-phosphate synthase [ammonia], mitochondrial CPS1 Tclin Enzyme -2.28267 188.9 238
Disabled homolog 2 DAB2 Tbio Non-IDG -2.26146 184.8 239