Development Level

Tbio 49 | 11,445
Tchem 15 | 1,598
Tdark 11 | 6,588
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 7 | 499
abnormal embryo size 5 | 220
embryonic lethality prior to t... 4 | 278
edema 3 | 59
decreased body weight 2 | 161
decreased lean body mass 2 | 135
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal facial morphology 1 | 17
abnormal joint morphology 1 | 23
abnormal limb bud morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal placenta vasculature 1 | 2
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
anophthalmia 1 | 33
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased anxiety-related resp... 1 | 12
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fluid intake 1 | 3
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hemorrhage 1 | 23
hydroencephaly 1 | 14
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
prenatal lethality 1 | 28
respiratory system phenotype 1 | 2
shortened RR interval 1 | 17
small adrenal glands 1 | 16
syndactyly 1 | 23
thrombocytopenia 1 | 56

Disease

Carcinoma 62 | 11,493
osteosarcoma 40 | 7,950
ovarian cancer 38 | 8,520
psoriasis 37 | 6,694
atypical teratoid / rhabdoid tumor 25 | 5,112
glioblastoma 24 | 5,792
medulloblastoma, large-cell 24 | 6,241
Kidney cancer 23 | 2,613
Kidney disease 23 | 430
ependymoma 22 | 4,679
lung cancer 22 | 4,740
malignant mesothelioma 21 | 3,232
Breast cancer 19 | 3,578
Cancer 16 | 2,499
group 3 medulloblastoma 16 | 4,104
non-small cell lung cancer 16 | 2,890
primitive neuroectodermal tumor 15 | 3,035
adult high grade glioma 14 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
pancreatic cancer 14 | 2,398
subependymal giant cell astrocytoma 14 | 2,287
Gout 13 | 106
lung adenocarcinoma 13 | 2,716
oligodendroglioma 13 | 2,850
Autosomal recessive predisposition 12 | 1,442
astrocytic glioma 12 | 2,597
cystic fibrosis 11 | 1,696
diabetes mellitus 11 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
Astrocytoma, Pilocytic 10 | 3,081
group 4 medulloblastoma 10 | 1,855
interstitial cystitis 10 | 2,312
lung carcinoma 10 | 2,843
pituitary cancer 10 | 1,972
Pick disease 9 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
primary pancreatic ductal adenocarcinoma 9 | 1,109
tuberculosis 9 | 2,010
Intellectual disability 8 | 1,016
acute quadriplegic myopathy 8 | 1,158
adrenocortical carcinoma 8 | 1,428
pediatric high grade glioma 8 | 1,064
ulcerative colitis 8 | 1,819
Cognitive delay 7 | 608
Dull intelligence 7 | 645
Global developmental delay 7 | 608
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental and motor retardation 7 | 608
Mental deficiency 7 | 645
Poor school performance 7 | 645
breast carcinoma 7 | 1,638
nephrosclerosis 7 | 333
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
spina bifida 7 | 1,074
Atopic dermatitis 6 | 952
Melanoma 6 | 711
Renal Insufficiency 6 | 90
Rheumatoid arthritis 6 | 1,191
Short stature 6 | 531
Skin cancer 6 | 469
colon cancer 6 | 1,478
esophageal adenocarcinoma 6 | 737
gastric carcinoma 6 | 807
Amyotrophic lateral sclerosis 5 | 451
Cardiomyopathy 5 | 116
Duchenne muscular dystrophy 5 | 601
Epilepsy 5 | 792
Kidney Diseases 5 | 114
Kidney Failure 5 | 111
Multiple myeloma 5 | 1,332
Obesity 5 | 678
Osteoporosis 5 | 363
Renal failure in adulthood 5 | 76
astrocytoma 5 | 1,146
cystic fibrosis and chronic rhinosinusitis 5 | 214
Acquired metabolic disease 4 | 336
Alzheimer's disease 4 | 658
Atherosclerosis 4 | 291
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Glaucoma 4 | 239
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Multiple Sclerosis 4 | 540
Muscle hypotonia 4 | 571
Parkinson's disease 4 | 392
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
cutaneous lupus erythematosus 4 | 1,057
ductal carcinoma in situ 4 | 1,745
medulloblastoma 4 | 720
mucosa-associated lymphoid tissue lymphoma 4 | 484
periodontitis 4 | 293
primary Sjogren syndrome 4 | 735
progressive supranuclear palsy 4 | 676
Bipolar Disorder 3 | 666
acute myeloid leukemia 3 | 783
dermatomyositis 3 | 966
juvenile dermatomyositis 3 | 1,187

Tissue

Endocrine System 74 | 18,159
Male tissues 74 | 17,142
Liver and Pancreas 73 | 16,750
Skin and soft tissues 73 | 17,230
Urinary Tract 73 | 16,678
Digestive Tract 72 | 17,369
Female tissues 72 | 17,400
Nervous System 72 | 16,725
Respiratory system 68 | 16,393
Blood and immune system 67 | 16,909
Cardiovascular System 61 | 15,192

Target Family

Non-IDG 42 | 12,091
Enzyme 16 | 4,145
Transcription Factor 7 | 1,400
Transporter 6 | 473
Kinase 3 | 634
Ion Channel 2 | 344
Epigenetic 1 | 242
GPCR 1 | 408

GWAS Trait

Glomerular filtration rate (cr... 78 | 78
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome P450 26A1 CYP26A1 Tchem Enzyme -2.44772 290.1 197
Pro-neuregulin-4, membrane-bound isoform NRG4 Tbio Non-IDG -1.33564 24.6 137
Protein arginine N-methyltransferase 7 PRMT7 Tchem Epigenetic -1.32370 24.3 163
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
R3H domain-containing protein 2 R3HDM2 Tdark Non-IDG -0.82119 4.93 39
Junctophilin-2 JPH2 Tbio Non-IDG -2.21890 163.0 229
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
Cyclin-dependent kinase 12 CDK12 Tchem Kinase -1.38476 29.4 157
Zinc finger protein 607 ZNF607 Tdark Transcription Factor 0.95 0.09 77