Development Level

Tbio 10 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

decreased circulating glucose ... 2 | 126
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
absent pinna reflex 1 | 23
cataract 1 | 92
corneal opacity 1 | 32
decreased caudal vertebrae num... 1 | 53
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
fused cornea and lens 1 | 5
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating free fat... 1 | 20
increased circulating potassiu... 1 | 29
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 9 | 11,493
psoriasis 8 | 6,694
ependymoma 7 | 4,679
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
ovarian cancer 6 | 8,520
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
astrocytic glioma 4 | 2,597
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
osteosarcoma 4 | 7,950
ulcerative colitis 4 | 1,819
Astrocytoma, Pilocytic 3 | 3,081
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
Autosomal recessive predisposition 2 | 1,442
Chronic Lymphocytic Leukemia 2 | 262
active Crohn's disease 2 | 922
astrocytoma 2 | 1,146
cutaneous lupus erythematosus 2 | 1,057
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
non-small cell lung cancer 2 | 2,890
Achromasia 1 | 11
Adenocarcinoma 1 | 122
Albinism 1 | 11
Amphetamine-Related Disorders 1 | 74
Atopic dermatitis 1 | 952
Attention deficit hyperactivity disorder 1 | 278
Autistic Disorder 1 | 364
Bipolar Disorder 1 | 666
Carcinoma of colon 1 | 32
Carcinoma, Renal Cell 1 | 124
Cerebrovascular disease 1 | 238
Chediak-Higashi syndrome 1 | 26
Chloracne 1 | 32
Chromosome 9p deletion syndrome 1 | 13
Colitis, Ulcerative 1 | 59
Congenital myasthenic syndrome 6 1 | 17
Craniofacial Abnormalities 1 | 151
Crohn's disease 1 | 321
Dacryocystitis 1 | 11
Down syndrome 1 | 499
Endometriosis 1 | 540
Freckles 1 | 33
Gaucher disease type 1 1 | 180
Glaucoma 1 | 239
Hermansky-Pudlak syndrome 1 | 42
Iris disease 1 | 10
Lung Neoplasms 1 | 232
Melanoma 1 | 711
Microphthalmia 1 | 76
Ocular albinism 1 | 26
Oculocutaneous albinism 1 | 29
Piebaldism 1 | 15
Pigment dispersion syndrome 1 | 11
Pigmentary iris degeneration 1 | 20
Pyoderma gangrenosum 1 | 9
Renal Cell Carcinoma 1 | 214
Retinitis pigmentosa 11 1 | 59
Retinitis pigmentosa 13 1 | 11
Rheumatoid arthritis 1 | 1,191
Schizophrenia 1 | 1,160
Simpson-Golabi-Behmel syndrome 1 | 19
Skin cancer 1 | 469
Strabismus 1 | 270
Typhoid fever 1 | 22
Vitiligo 1 | 73
Waardenburg's syndrome 1 | 17
Waldenstrons macroglobulinemia 1 | 765
Xeroderma pigmentosum 1 | 43
active ulcerative colitis 1 | 764
aldosterone-producing adenoma 1 | 665
breast carcinoma 1 | 1,638
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
ductal carcinoma in situ 1 | 1,745
glioblastoma multiforme 1 | 142
inflammatory breast cancer 1 | 286
juvenile dermatomyositis 1 | 1,187
lung carcinoma 1 | 2,843
nasopharyngeal carcinoma 1 | 1,058
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
primary Sjogren syndrome 1 | 735
primary pancreatic ductal adenocarcinoma 1 | 1,109
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 162

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Male tissues 12 | 17,142
Skin and soft tissues 12 | 17,230
Cardiovascular System 11 | 15,192
Liver and Pancreas 11 | 16,750
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Urinary Tract 11 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 5 | 4,145
Transcription Factor 1 | 1,400

GWAS Trait

Facial morphology (factor 23) 12 | 12
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Death domain-containing protein CRADD CRADD Tbio Non-IDG -1.34614 23.0 400
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tbio Enzyme -2.95336 876.7 309
Reticulon-4 receptor-like 1 RTN4RL1 Tbio Non-IDG -0.81334 6.43 92
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 AGAP1 Tbio Enzyme -0.83079 8.71 94
Defensin-6 DEFA6 Tbio Non-IDG -1.25739 19.3 70
Ubiquitin carboxyl-terminal hydrolase 48 USP48 Tbio Enzyme -0.56820 3.47 116
Replication protein A 70 kDa DNA-binding subunit RPA1 Tchem Non-IDG -2.48277 297.9 350
TBC1 domain family member 22A TBC1D22A Tbio Non-IDG -0.34282 1.72 112
UDP-glucuronic acid decarboxylase 1 UXS1 Tbio Enzyme -0.99024 10.1 93
Kinetochore protein Nuf2 NUF2 Tbio Non-IDG -1.70027 49.7 117