Development Level

Tbio 6 | 11,445
Tdark 6 | 6,588
Tchem 1 | 1,598

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal body wall morphology 1 | 9
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal limb morphology 1 | 13
abnormal liver morphology 1 | 17
anophthalmia 1 | 33
decreased body length 1 | 101
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
improved glucose tolerance 1 | 79
microphthalmia 1 | 26
polydactyly 1 | 7
preweaning lethality, complete... 1 | 979
protruding tongue 1 | 3

Disease

Carcinoma 9 | 11,493
osteosarcoma 9 | 7,950
psoriasis 7 | 6,694
ependymoma 6 | 4,679
medulloblastoma, large-cell 6 | 6,241
ovarian cancer 6 | 8,520
Breast cancer 5 | 3,578
atypical teratoid / rhabdoid tumor 5 | 5,112
ductal carcinoma in situ 5 | 1,745
glioblastoma 5 | 5,792
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
Kidney cancer 4 | 2,613
breast carcinoma 4 | 1,638
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Acquired metabolic disease 3 | 336
adult high grade glioma 3 | 3,801
cystic fibrosis 3 | 1,696
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pancreatic carcinoma 3 | 562
primitive neuroectodermal tumor 3 | 3,035
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Down syndrome 2 | 499
Dull intelligence 2 | 645
Epilepsy 2 | 792
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Osteoporosis 2 | 363
Pick disease 2 | 1,894
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Seizures 2 | 596
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
cutaneous lupus erythematosus 2 | 1,057
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
tuberculosis 2 | 2,010
tuberculosis and treatment for 6 months 2 | 409
ulcerative colitis 2 | 1,819
Achalasia 1 | 13
Anodontia 1 | 12
Autism Spectrum Disorders 1 | 75
Carcinoma of colon 1 | 32
Carcinoma, Squamous Cell 1 | 110
Common variable immunodeficiency 1 | 101
Cortical Dysplasia-Focal Epilepsy Syndrome 1 | 2
Decreased projection of maxilla 1 | 66
Deficiency of upper jaw bones 1 | 66
Delayed Puberty 1 | 97
Dental caries 1 | 164
Dyslexia 1 | 43
Epileptic encephalopathy 1 | 26
Familial adenomatous polyposis 1 | 32
Gilles de la Tourette syndrome 1 | 47
Gonadal Dysgenesis 1 | 28
Gonadal Dysgenesis, Mixed 1 | 19
Gross motor development delay 1 | 21
Hyperactive behavior 1 | 91
Hypodontia 1 | 81
Hypohidrotic ectodermal dysplasia 1 | 15
Hypoplasia of the maxilla 1 | 66
Hypotrophic maxilla 1 | 66
Language Development Disorders 1 | 11
Low serum estradiol levels 1 | 22
Maxillary retrognathia 1 | 66
Meniere's disease 1 | 24
Muscle Rigidity 1 | 49
Oligodontia 1 | 24
Pitt-Hopkins syndrome 1 | 20
Primary physiologic amenorrhea 1 | 55
Renal Cell Carcinoma 1 | 214
Retrusion of upper jaw bones 1 | 66
Small testicle 1 | 75
Specific language impairment 1 | 34
Tooth agenesis 1 | 44
axial spondyloarthropathy 1 | 28
chronic kidney disease 1 | 90

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230

Target Family

Non-IDG 7 | 12,091
Enzyme 5 | 4,145
GPCR 1 | 408

GWAS Trait

Facial morphology (factor 11, ... 13 | 13
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WW domain-containing oxidoreductase WWOX Tbio Enzyme -3.61683 3311.4 251
Axin-2 AXIN2 Tchem Non-IDG -2.44870 241.5 237
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC MAN1C1 Tdark Enzyme -2.26298 170.7 37
Syntaxin-11 STX11 Tbio Non-IDG -1.61484 45.0 136
Nuclear pore complex-interacting protein family member B11 NPIPB11 Tdark Non-IDG -1.36441 22.2 0
A disintegrin and metalloproteinase with thrombospondin motifs 10 ADAMTS10 Tbio Enzyme -1.35665 21.7 120
G-protein coupled receptor family C group 5 member B GPRC5B Tbio GPCR -1.15139 13.4 213
Signal peptidase complex subunit 3 SPCS3 Tdark Enzyme -0.52720 4.04 50
[F-actin]-monooxygenase MICAL2 MICAL2 Tbio Enzyme -0.47649 3.62 57