Development Level

Tbio 2 | 11,445
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

embryonic lethality prior to t... 1 | 278
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 4 | 11,493
Heart disease 4 | 306
Kidney cancer 3 | 2,613
medulloblastoma, large-cell 3 | 6,241
Breast cancer 2 | 3,578
Myocardial Infarction 2 | 151
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
psoriasis 2 | 6,694
Abnormal hair whorls 1 | 5
Abnormality of retinal pigmentation 1 | 111
Abnormality of the thorax 1 | 19
Abnormality of the voice 1 | 46
Aplasia/Hypoplasia of the skin 1 | 16
Arrhythmogenic right ventricular cardiomyopathy 1 | 30
Autism Spectrum Disorders 1 | 75
Autism spectrum disorder 1 | 101
Baller-Gerold syndrome 1 | 12
Bloom syndrome 1 | 29
COPD 1 | 118
Calcium pyrophosphate deposition disease 1 | 13
Cardiac Arrhythmia 1 | 103
Cardiomyopathy 1 | 116
Cardiomyopathy, right ventricular 1 | 7
Catecholaminergic polymorphic ventricular tachycardia 1 | 12
Chronic heart failure 1 | 46
Cockayne syndrome 1 | 60
Congenital stationary night blindness 1 | 29
Congenital stationary night blindness 1B 1 | 6
Congestive heart failure 1 | 113
Convex nasal ridge 1 | 37
DOID:2627 1 | 94
Decreased fertility 1 | 33
Diabetic Cardiomyopathies 1 | 10
Dizziness 1 | 26
Entropion 1 | 22
Familial atrial fibrillation 1 | 23
Fanconi anemia 1 | 56
Hair shaft abnormalities 1 | 30
Heart failure 1 | 162
Hyperkeratosis 1 | 50
Hypertensive disorder 1 | 56
Insulin Resistance 1 | 72
Lack of skin elasticity 1 | 10
Lipoatrophy 1 | 19
Liver cancer 1 | 604
Lymphoid leukemia 1 | 160
Malignant hyperthermia 1 | 26
Meningioma 1 | 41
Mesothelioma, Malignant 1 | 105
Myopathy 1 | 185
NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1F 1 | 1
Narrow face 1 | 54
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Night blindness, congenital stationary 1 | 16
Nijmegen breakage syndrome 1 | 24
Osteoporosis 1 | 363
Osteosclerosis 1 | 31
Paroxysmal familial ventricular fibrillation 1 1 | 4
Photosensitive trichothiodystrophy 1 | 30
Pili Torti 1 | 6
Premature arteriosclerosis 1 | 5
Premature canities 1 | 24
Premature hardening of arteries 1 | 5
Progeria 1 | 25
Pulmonary artery stenosis 1 | 22
Rapadilino syndrome 1 | 7
Retinal Degeneration 1 | 106
Retinal pigment epithelial abnormality 1 | 111
Rothmund-Thomson syndrome 1 | 19
Skeletal muscle atrophy 1 | 139
Skin Ulcer 1 | 48
Slender build 1 | 14
Small hand 1 | 36
Sparse scalp hair 1 | 42
Stretched skin 1 | 10
Subcutaneous calcification 1 | 2
Sudden death 1 | 16
Syncope 1 | 22
Tachycardia 1 | 43
Tachycardia, Ventricular 1 | 22
Telangiectasia of the skin 1 | 39
Thin face 1 | 54
VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder) 1 | 5
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy 1 | 4
Ventricular aneurysm 1 | 2
Ventricular arrhythmia 1 | 27
Vertical Talus 1 | 25
Vertigo 1 | 29
Warsaw breakage syndrome 1 | 11
Werner syndrome 1 | 29
White forelock 1 | 12
Wizened face 1 | 9
Xeroderma pigmentosum 1 | 43
facioscapulohumeral dystrophy 1 | 288
hair abnormalities (non-specific) 1 | 30
muscle degeneration 1 | 139
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 4 | 16,909
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Cardiovascular System 3 | 15,192

Target Family

Enzyme 2 | 4,145
Ion Channel 1 | 344
Non-IDG 1 | 12,091

GWAS Trait

Exercise treadmill test traits 4 | 4
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ryanodine receptor 2 RYR2 Tclin Ion Channel -2.92980 851.9 138
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 LRIT3 Tbio Non-IDG -0.43688 4.17 64
Probable ribonuclease ZC3H12C ZC3H12C Tdark Enzyme -0.40792 1.91 42
Werner syndrome ATP-dependent helicase WRN Tbio Enzyme -2.73759 569.7 210